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Murcko scaffold

Ring system with 3 rings and 20 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
10
With full pages
4
Scaffold SMILES

O=C(Nc1ccccc1)NC1CCOc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)NC1CCOc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-[6-Bromo-3-(hydroxymethyl)-3,4-dihydro-2H-chromen-4-yl]-N-methyl-N'-phenylurea chemical structure, C18H19BrN2O3, CAS 400089-17-0
N-[6-Bromo-3-(hydroxymethyl)-3,4-dihydro-2H-chromen-4-yl]-N-methyl-N'-phenylurea
CAS 400089-17-0C18H19BrN2O3
N-[6-Bromo-3-(hydroxymethyl)-3,4-dihydro-2H-chromen-4-yl]-N-methyl-N'-[3-(trifluoromethyl)phenyl]urea chemical structure, C19H18BrF3N2O3, CAS 400089-19-2
N-[6-Bromo-3-(hydroxymethyl)-3,4-dihydro-2H-chromen-4-yl]-N-methyl-N'-[3-(trifluoromethyl)phenyl]urea
CAS 400089-19-2C19H18BrF3N2O3
N'-(4-Chlorophenyl)-N-[3-(hydroxymethyl)-8-methoxy-3,4-dihydro-2H-chromen-4-yl]-N-methylurea chemical structure, C19H21ClN2O4, CAS 318951-56-3
N'-(4-Chlorophenyl)-N-[3-(hydroxymethyl)-8-methoxy-3,4-dihydro-2H-chromen-4-yl]-N-methylurea
CAS 318951-56-3C19H21ClN2O4
N-[3-(Hydroxymethyl)-8-methoxy-3,4-dihydro-2H-chromen-4-yl]-N-methyl-N'-phenylurea chemical structure, C19H22N2O4, CAS 324009-17-8
N-[3-(Hydroxymethyl)-8-methoxy-3,4-dihydro-2H-chromen-4-yl]-N-methyl-N'-phenylurea
CAS 324009-17-8C19H22N2O4
N'-(2,4-Dichlorophenyl)-N-[3-(hydroxymethyl)-8-methoxy-3,4-dihydro-2H-chromen-4-yl]-N-methylurea chemical structure, C19H20Cl2N2O4, CAS 324009-18-9
N'-(2,4-Dichlorophenyl)-N-[3-(hydroxymethyl)-8-methoxy-3,4-dihydro-2H-chromen-4-yl]-N-methylurea
CAS 324009-18-9C19H20Cl2N2O4
N-[6-Bromo-3-(hydroxymethyl)-3,4-dihydro-2H-chromen-4-yl]-N'-(2,4-dichlorophenyl)-N-methylurea chemical structure, C18H17BrCl2N2O3, CAS 324009-22-5
N-[6-Bromo-3-(hydroxymethyl)-3,4-dihydro-2H-chromen-4-yl]-N'-(2,4-dichlorophenyl)-N-methylurea
CAS 324009-22-5C18H17BrCl2N2O3
N-[3-(Hydroxymethyl)-8-methoxy-3,4-dihydro-2H-chromen-4-yl]-N-methyl-N'-[3-(trifluoromethyl)phenyl]urea chemical structure, C20H21F3N2O4, CAS 324009-19-0
N-[3-(Hydroxymethyl)-8-methoxy-3,4-dihydro-2H-chromen-4-yl]-N-methyl-N'-[3-(trifluoromethyl)phenyl]urea
CAS 324009-19-0C20H21F3N2O4
1-Phenyl-3-(2,2,6-trimethyl-3,4-dihydro-2H-chromen-4-yl)urea chemical structure, C19H22N2O2, CAS 1269364-36-4
1-Phenyl-3-(2,2,6-trimethyl-3,4-dihydro-2H-chromen-4-yl)urea
CAS 1269364-36-4C19H22N2O2
tert-Butyl N-[4-[(3-cyanophenyl)carbamoylamino]-2,2-dimethyl-3,4-dihydrochromen-6-yl]carbamate chemical structure, C24H28N4O4, CAS 1392810-44-4
tert-Butyl N-[4-[(3-cyanophenyl)carbamoylamino]-2,2-dimethyl-3,4-dihydrochromen-6-yl]carbamate
CAS 1392810-44-4C24H28N4O4
Carbamic acid, N-[4-[[[(3-aminophenyl)amino]carbonyl]amino]-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl]-, 1,1-dimethylethyl ester chemical structure, C23H30N4O4, CAS 1393527-99-5
Carbamic acid, N-[4-[[[(3-aminophenyl)amino]carbonyl]amino]-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl]-, 1,1-dimethylethyl ester
CAS 1393527-99-5C23H30N4O4