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Murcko scaffold

4-[(4-Phenoxyphenyl)sulfonyl]morpholine scaffold

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
21
With full pages
7
Scaffold SMILES

O=S(=O)(c1ccc(Oc2ccccc2)cc1)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-[(4-Phenoxyphenyl)sulfonyl]morpholine page
Murcko scaffold O=S(=O)(c1ccc(Oc2ccccc2)cc1)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

4-((4-(2-Methoxyphenoxy)phenyl)sulfonyl)morpholine chemical structure, C17H19NO5S, CAS 612044-64-1
4-((4-(2-Methoxyphenoxy)phenyl)sulfonyl)morpholine
CAS 612044-64-1C17H19NO5S
4-[(4-Phenoxyphenyl)sulfonyl]morpholine chemical structure, C16H17NO4S, CAS 494838-95-8
4-[(4-Phenoxyphenyl)sulfonyl]morpholine
CAS 494838-95-8C16H17NO4S
4-{[4-(4-Nitrophenoxy)phenyl]sulfonyl}morpholine chemical structure, C16H16N2O6S, CAS 297743-47-6
4-{[4-(4-Nitrophenoxy)phenyl]sulfonyl}morpholine
CAS 297743-47-6C16H16N2O6S
2-Chloro-6-(4-morpholin-4-ylsulfonylphenoxy)benzonitrile chemical structure, C17H15ClN2O4S, CAS 662146-35-2
2-Chloro-6-(4-morpholin-4-ylsulfonylphenoxy)benzonitrile
CAS 662146-35-2C17H15ClN2O4S
Morpholine, 4-[[4-(2,6-dicyanophenoxy)phenyl]sulfonyl]- chemical structure, C18H15N3O4S, CAS 671183-51-0
Morpholine, 4-[[4-(2,6-dicyanophenoxy)phenyl]sulfonyl]-
CAS 671183-51-0C18H15N3O4S
2,6-Dimethyl-4-((4-phenoxyphenyl)sulfonyl)morpholine chemical structure, C18H21NO4S, CAS 314043-25-9
2,6-Dimethyl-4-((4-phenoxyphenyl)sulfonyl)morpholine
CAS 314043-25-9C18H21NO4S
4-((4-(o-Tolyloxy)phenyl)sulfonyl)morpholine chemical structure, C17H19NO4S, CAS 496026-11-0
4-((4-(o-Tolyloxy)phenyl)sulfonyl)morpholine
CAS 496026-11-0C17H19NO4S
2,6-Dimethyl-4-((4-(o-tolyloxy)phenyl)sulfonyl)morpholine chemical structure, C19H23NO4S, CAS 606944-34-7
2,6-Dimethyl-4-((4-(o-tolyloxy)phenyl)sulfonyl)morpholine
CAS 606944-34-7C19H23NO4S
4-((4-(2-Chlorophenoxy)phenyl)sulfonyl)morpholine chemical structure, C16H16ClNO4S, CAS 606944-68-7
4-((4-(2-Chlorophenoxy)phenyl)sulfonyl)morpholine
CAS 606944-68-7C16H16ClNO4S
2-(3-Bromophenoxy)-5-(4-morpholinylsulfonyl)benzenamine chemical structure, C16H17BrN2O4S, CAS 735322-77-7
2-(3-Bromophenoxy)-5-(4-morpholinylsulfonyl)benzenamine
CAS 735322-77-7C16H17BrN2O4S
2-(4-Fluorophenoxy)-5-(morpholine-4-sulfonyl)aniline chemical structure, C16H17FN2O4S, CAS 727694-62-4
2-(4-Fluorophenoxy)-5-(morpholine-4-sulfonyl)aniline
CAS 727694-62-4C16H17FN2O4S
5-(Morpholine-4-sulfonyl)-2-phenoxyaniline chemical structure, C16H18N2O4S, CAS 736948-90-6
5-(Morpholine-4-sulfonyl)-2-phenoxyaniline
CAS 736948-90-6C16H18N2O4S
2-(4-Ethoxyphenoxy)-5-(morpholine-4-sulfonyl)aniline chemical structure, C18H22N2O5S, CAS 735322-12-0
2-(4-Ethoxyphenoxy)-5-(morpholine-4-sulfonyl)aniline
CAS 735322-12-0C18H22N2O5S
4-[4-(3-Methoxyphenoxy)-3-nitrophenyl]sulfonylmorpholine chemical structure, C17H18N2O7S, CAS 761421-19-6
4-[4-(3-Methoxyphenoxy)-3-nitrophenyl]sulfonylmorpholine
CAS 761421-19-6C17H18N2O7S
3-Methoxy-4-(4-morpholin-4-ylsulfonyl-2-nitrophenoxy)benzaldehyde chemical structure, C18H18N2O8S, CAS 721414-37-5
3-Methoxy-4-(4-morpholin-4-ylsulfonyl-2-nitrophenoxy)benzaldehyde
CAS 721414-37-5C18H18N2O8S
2,6-Dinitro-4-(trifluoromethyl)phenyl 4-(morpholinosulfonyl)phenyl ether chemical structure, C17H14F3N3O8S, CAS 262439-64-5
2,6-Dinitro-4-(trifluoromethyl)phenyl 4-(morpholinosulfonyl)phenyl ether
CAS 262439-64-5C17H14F3N3O8S
1-{2-Chloro-6-[4-(morpholine-4-sulfonyl)phenoxy]phenyl}methanamine chemical structure, C17H19ClN2O4S, CAS 823780-80-9
1-{2-Chloro-6-[4-(morpholine-4-sulfonyl)phenoxy]phenyl}methanamine
CAS 823780-80-9C17H19ClN2O4S
{2-[4-(Morpholine-4-sulfonyl)phenoxy]-1,3-phenylene}dimethanamine chemical structure, C18H23N3O4S, CAS 823780-86-5
{2-[4-(Morpholine-4-sulfonyl)phenoxy]-1,3-phenylene}dimethanamine
CAS 823780-86-5C18H23N3O4S
4-[4-(Morpholin-4-ylsulfonyl)phenoxy]-3-(trifluoromethyl)aniline chemical structure, C17H17F3N2O4S, CAS 1858251-05-4
4-[4-(Morpholin-4-ylsulfonyl)phenoxy]-3-(trifluoromethyl)aniline
CAS 1858251-05-4C17H17F3N2O4S
4-((4-[4-Nitro-2-(trifluoromethyl)phenoxy]phenyl)sulfonyl)morpholine chemical structure, C17H15F3N2O6S, CAS 1858242-18-8
4-((4-[4-Nitro-2-(trifluoromethyl)phenoxy]phenyl)sulfonyl)morpholine
CAS 1858242-18-8C17H15F3N2O6S
5-(Morpholine-4-sulfonyl)-2-phenoxy-N-(prop-2-yn-1-yl)aniline chemical structure, C19H20N2O4S, CAS 2308435-42-7
5-(Morpholine-4-sulfonyl)-2-phenoxy-N-(prop-2-yn-1-yl)aniline
CAS 2308435-42-7C19H20N2O4S