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Murcko scaffold

Ring system with 3 rings and 22 atoms

55 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
55
With full pages
9
Scaffold SMILES

O=C(Nc1ccc(Cc2ccccc2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(Cc2ccccc2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 55 chemicals

Closantel chemical structure, C22H14Cl2I2N2O2, CAS 57808-65-8
Closantel
CAS 57808-65-8C22H14Cl2I2N2O2
N-{5-Chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}benzamide chemical structure, C22H16Cl2N2O, CAS 710289-91-1
N-{5-Chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}benzamide
CAS 710289-91-1C22H16Cl2N2O
N-{5-Chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-4-nitrobenzamide chemical structure, C22H15Cl2N3O3, CAS 710973-57-2
N-{5-Chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-4-nitrobenzamide
CAS 710973-57-2C22H15Cl2N3O3
N-{5-Chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-4-methoxy-3-nitrobenzamide chemical structure, C23H17Cl2N3O4, CAS 710975-97-6
N-{5-Chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-4-methoxy-3-nitrobenzamide
CAS 710975-97-6C23H17Cl2N3O4
N-[5-Chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]-3,4-diethoxybenzamide chemical structure, C26H24Cl2N2O3, CAS 710976-79-7
N-[5-Chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]-3,4-diethoxybenzamide
CAS 710976-79-7C26H24Cl2N2O3
Methyl 3-({5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}carbamoyl)-5-nitrobenzoate chemical structure, C24H17Cl2N3O5, CAS 825598-31-0
Methyl 3-({5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}carbamoyl)-5-nitrobenzoate
CAS 825598-31-0C24H17Cl2N3O5
N-[5-Chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]-2-methoxy-4-methylsulfanylbenzamide chemical structure, C24H20Cl2N2O2S, CAS 825598-66-1
N-[5-Chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]-2-methoxy-4-methylsulfanylbenzamide
CAS 825598-66-1C24H20Cl2N2O2S
N-(5-Chloro-4-((4-chlorophenyl)cyanomethyl)-2-(isopropyl)phenyl)-2-hydroxy-3,5-diiodobenzamide chemical structure, C24H18Cl2I2N2O2, CAS 61438-63-9
N-(5-Chloro-4-((4-chlorophenyl)cyanomethyl)-2-(isopropyl)phenyl)-2-hydroxy-3,5-diiodobenzamide
CAS 61438-63-9C24H18Cl2I2N2O2
ZT-1a chemical structure, C22H15Cl3N2O2, CAS 212135-62-1
ZT-1a
CAS 212135-62-1C22H15Cl3N2O2
N-(5-Chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)-3-propionamidobenzamide chemical structure, C25H21Cl2N3O2, CAS 881795-95-5
N-(5-Chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)-3-propionamidobenzamide
CAS 881795-95-5C25H21Cl2N3O2
N-{4-[(4-Aminophenyl)methyl]phenyl}benzamide chemical structure, C20H18N2O, CAS 99634-56-7
N-{4-[(4-Aminophenyl)methyl]phenyl}benzamide
CAS 99634-56-7C20H18N2O
N-{3-Chloro-4-[cyano(phenyl)methyl]phenyl}-2,6-dihydroxybenzamide chemical structure, C21H15ClN2O3, CAS 61438-69-5
N-{3-Chloro-4-[cyano(phenyl)methyl]phenyl}-2,6-dihydroxybenzamide
CAS 61438-69-5C21H15ClN2O3
N-{4-[Cyano(phenyl)methyl]phenyl}-2-hydroxybenzamide chemical structure, C21H16N2O2, CAS 61438-59-3
N-{4-[Cyano(phenyl)methyl]phenyl}-2-hydroxybenzamide
CAS 61438-59-3C21H16N2O2
N-{4-[Cyano(4-methylphenyl)methyl]phenyl}-2-hydroxybenzamide chemical structure, C22H18N2O2, CAS 61438-60-6
N-{4-[Cyano(4-methylphenyl)methyl]phenyl}-2-hydroxybenzamide
CAS 61438-60-6C22H18N2O2
N-{4-[Cyano(4-methylphenyl)methyl]phenyl}-2,6-dihydroxybenzamide chemical structure, C22H18N2O3, CAS 61438-68-4
N-{4-[Cyano(4-methylphenyl)methyl]phenyl}-2,6-dihydroxybenzamide
CAS 61438-68-4C22H18N2O3
N-{5-Chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxybenzamide chemical structure, C22H16Cl2N2O2, CAS 61439-05-2
N-{5-Chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxybenzamide
CAS 61439-05-2C22H16Cl2N2O2
N-{4-[Cyano(4-methoxyphenyl)methyl]phenyl}-2,6-dihydroxybenzamide chemical structure, C22H18N2O4, CAS 61438-71-9
N-{4-[Cyano(4-methoxyphenyl)methyl]phenyl}-2,6-dihydroxybenzamide
CAS 61438-71-9C22H18N2O4
N-{4-[Cyano(phenyl)methyl]phenyl}-2,6-dihydroxybenzamide chemical structure, C21H16N2O3, CAS 61438-70-8
N-{4-[Cyano(phenyl)methyl]phenyl}-2,6-dihydroxybenzamide
CAS 61438-70-8C21H16N2O3
N-{4-[Cyano(phenyl)methyl]phenyl}-2-hydroxy-3,5-diiodobenzamide chemical structure, C21H14I2N2O2, CAS 61438-38-8
N-{4-[Cyano(phenyl)methyl]phenyl}-2-hydroxy-3,5-diiodobenzamide
CAS 61438-38-8C21H14I2N2O2
N-{4-[Cyano(4-fluorophenyl)methyl]phenyl}-2,6-dihydroxybenzamide chemical structure, C21H15FN2O3, CAS 61438-67-3
N-{4-[Cyano(4-fluorophenyl)methyl]phenyl}-2,6-dihydroxybenzamide
CAS 61438-67-3C21H15FN2O3
Closantel sodium chemical structure, C22H13Cl2I2N2NaO2, CAS 61438-64-0
Closantel sodium
CAS 61438-64-0C22H13Cl2I2N2NaO2
Benzamide, N-[5-chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodo-, sodium salt (1:1) chemical structure, C22H14Cl2I2N2NaO2+
Benzamide, N-[5-chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodo-, sodium salt (1:1)
C22H14Cl2I2N2NaO2+
Benzamide, N-[3-chloro-4-(cyanophenylmethyl)phenyl]-4-[[(1-methylpropyl)amino]sulfonyl]- chemical structure, C25H24ClN3O3S, CAS 1302000-00-5
Benzamide, N-[3-chloro-4-(cyanophenylmethyl)phenyl]-4-[[(1-methylpropyl)amino]sulfonyl]-
CAS 1302000-00-5C25H24ClN3O3S
N-(3-Chloro-4-(cyano(phenyl)methyl)phenyl)-3-propionamidobenzamide chemical structure, C24H20ClN3O2, CAS 1277620-87-7
N-(3-Chloro-4-(cyano(phenyl)methyl)phenyl)-3-propionamidobenzamide
CAS 1277620-87-7C24H20ClN3O2