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Murcko scaffold

Ring system with 3 rings and 19 atoms

99 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
99
With full pages
15
Scaffold SMILES

c1ccc(CSc2nnc(-c3ccccc3)o2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CSc2nnc(-c3ccccc3)o2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 99 chemicals

2-Benzylsulfanyl-5-(2,4-dichloro-phenyl)-[1,3,4]oxadiazole chemical structure, C15H10Cl2N2OS, CAS 313958-75-7
2-Benzylsulfanyl-5-(2,4-dichloro-phenyl)-[1,3,4]oxadiazole
CAS 313958-75-7C15H10Cl2N2OS
RefChem:381391 chemical structure, C20H19ClN2O2S, CAS 5777-11-7
RefChem:381391
CAS 5777-11-7C20H19ClN2O2S
2-[(4-Methoxybenzyl)sulfanyl]-5-(4-methoxyphenyl)-1,3,4-oxadiazole chemical structure, C17H16N2O3S, CAS 311793-82-5
2-[(4-Methoxybenzyl)sulfanyl]-5-(4-methoxyphenyl)-1,3,4-oxadiazole
CAS 311793-82-5C17H16N2O3S
4-[5-(Benzylsulfanyl)-1,3,4-oxadiazol-2-yl]-N,N-dimethylaniline chemical structure, C17H17N3OS, CAS 431076-00-5
4-[5-(Benzylsulfanyl)-1,3,4-oxadiazol-2-yl]-N,N-dimethylaniline
CAS 431076-00-5C17H17N3OS
2-((4-Methylbenzyl)thio)-5-phenyl-1,3,4-oxadiazole chemical structure, C16H14N2OS, CAS 336177-59-4
2-((4-Methylbenzyl)thio)-5-phenyl-1,3,4-oxadiazole
CAS 336177-59-4C16H14N2OS
2-[(4-Bromobenzyl)sulfanyl]-5-phenyl-1,3,4-oxadiazole chemical structure, C15H11BrN2OS, CAS 331418-71-4
2-[(4-Bromobenzyl)sulfanyl]-5-phenyl-1,3,4-oxadiazole
CAS 331418-71-4C15H11BrN2OS
2-Benzylsulfanyl-5-(2-chlorophenyl)-1,3,4-oxadiazole chemical structure, C15H11ClN2OS, CAS 58695-70-8
2-Benzylsulfanyl-5-(2-chlorophenyl)-1,3,4-oxadiazole
CAS 58695-70-8C15H11ClN2OS
2-(4-Methylphenyl)-5-[(2,4,6-trimethylphenyl)methylsulfanyl]-1,3,4-oxadiazole chemical structure, C19H20N2OS, CAS 330466-10-9
2-(4-Methylphenyl)-5-[(2,4,6-trimethylphenyl)methylsulfanyl]-1,3,4-oxadiazole
CAS 330466-10-9C19H20N2OS
2-(Benzylsulfanyl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole chemical structure, C16H14N2O2S, CAS 197371-67-8
2-(Benzylsulfanyl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole
CAS 197371-67-8C16H14N2O2S
2-(2-Chlorophenyl)-5-[(4-nitrophenyl)methylsulfanyl]-1,3,4-oxadiazole chemical structure, C15H10ClN3O3S, CAS 332126-67-7
2-(2-Chlorophenyl)-5-[(4-nitrophenyl)methylsulfanyl]-1,3,4-oxadiazole
CAS 332126-67-7C15H10ClN3O3S
2-((4-Nitrobenzyl)thio)-5-phenyl-1,3,4-oxadiazole chemical structure, C15H11N3O3S, CAS 116987-25-8
2-((4-Nitrobenzyl)thio)-5-phenyl-1,3,4-oxadiazole
CAS 116987-25-8C15H11N3O3S
2-(Benzylthio)-5-(p-tolyl)-1,3,4-oxadiazole chemical structure, C16H14N2OS, CAS 71134-64-0
2-(Benzylthio)-5-(p-tolyl)-1,3,4-oxadiazole
CAS 71134-64-0C16H14N2OS
2-[(2,4-Dichlorobenzyl)sulfanyl]-5-phenyl-1,3,4-oxadiazole chemical structure, C15H10Cl2N2OS, CAS 28923-56-0
2-[(2,4-Dichlorobenzyl)sulfanyl]-5-phenyl-1,3,4-oxadiazole
CAS 28923-56-0C15H10Cl2N2OS
2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-5-phenyl-1,3,4-oxadiazole chemical structure, C15H10ClFN2OS, CAS 312705-29-6
2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-5-phenyl-1,3,4-oxadiazole
CAS 312705-29-6C15H10ClFN2OS
2-(Benzylsulfanyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole chemical structure, C15H11N3O3S, CAS 58695-72-0
2-(Benzylsulfanyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole
CAS 58695-72-0C15H11N3O3S
2-(Benzylsulfanyl)-5-(2-methoxyphenyl)-1,3,4-oxadiazole chemical structure, C16H14N2O2S, CAS 314030-29-0
2-(Benzylsulfanyl)-5-(2-methoxyphenyl)-1,3,4-oxadiazole
CAS 314030-29-0C16H14N2O2S
2-((4-Methylbenzyl)thio)-5-(4-nitrophenyl)-1,3,4-oxadiazole chemical structure, C16H13N3O3S, CAS 332869-58-6
2-((4-Methylbenzyl)thio)-5-(4-nitrophenyl)-1,3,4-oxadiazole
CAS 332869-58-6C16H13N3O3S
2-((4-Chlorobenzyl)thio)-5-(4-chlorophenyl)-1,3,4-oxadiazole chemical structure, C15H10Cl2N2OS, CAS 119611-15-3
2-((4-Chlorobenzyl)thio)-5-(4-chlorophenyl)-1,3,4-oxadiazole
CAS 119611-15-3C15H10Cl2N2OS
4-(5-((4-Methylbenzyl)thio)-1,3,4-oxadiazol-2-yl)phenol chemical structure, C16H14N2O2S, CAS 482613-68-3
4-(5-((4-Methylbenzyl)thio)-1,3,4-oxadiazol-2-yl)phenol
CAS 482613-68-3C16H14N2O2S
4-(5-((2-Chlorobenzyl)thio)-1,3,4-oxadiazol-2-yl)phenol chemical structure, C15H11ClN2O2S, CAS 493032-79-4
4-(5-((2-Chlorobenzyl)thio)-1,3,4-oxadiazol-2-yl)phenol
CAS 493032-79-4C15H11ClN2O2S
2-((4-Chlorobenzyl)thio)-5-(m-tolyl)-1,3,4-oxadiazole chemical structure, C16H13ClN2OS, CAS 332380-87-7
2-((4-Chlorobenzyl)thio)-5-(m-tolyl)-1,3,4-oxadiazole
CAS 332380-87-7C16H13ClN2OS
2-((2-Chlorobenzyl)thio)-5-(2-chlorophenyl)-1,3,4-oxadiazole chemical structure, C15H10Cl2N2OS, CAS 332175-46-9
2-((2-Chlorobenzyl)thio)-5-(2-chlorophenyl)-1,3,4-oxadiazole
CAS 332175-46-9C15H10Cl2N2OS
2-(Benzylsulfanyl)-5-(3,4-dimethoxyphenyl)-1,3,4-oxadiazole chemical structure, C17H16N2O3S, CAS 486397-88-0
2-(Benzylsulfanyl)-5-(3,4-dimethoxyphenyl)-1,3,4-oxadiazole
CAS 486397-88-0C17H16N2O3S
2-[(2,4-Dimethylphenyl)methylsulfanyl]-5-(4-methylphenyl)-1,3,4-oxadiazole chemical structure, C18H18N2OS, CAS 371951-69-8
2-[(2,4-Dimethylphenyl)methylsulfanyl]-5-(4-methylphenyl)-1,3,4-oxadiazole
CAS 371951-69-8C18H18N2OS