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Murcko scaffold

N-Phenyl-4-thiophen-2-yl-1,3-thiazol-2-amine scaffold

26 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
26
With full pages
4
Scaffold SMILES

c1ccc(Nc2nc(-c3cccs3)cs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-4-thiophen-2-yl-1,3-thiazol-2-amine page
Murcko scaffold c1ccc(Nc2nc(-c3cccs3)cs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

2-{2-[(3,4-Dimethylphenyl)amino]-4-(2-thienyl)-1,3-thiazol-5-yl}acetic acid chemical structure, C17H16N2O2S2, CAS 315709-86-5
2-{2-[(3,4-Dimethylphenyl)amino]-4-(2-thienyl)-1,3-thiazol-5-yl}acetic acid
CAS 315709-86-5C17H16N2O2S2
N-(2-Fluorophenyl)-4-thiophen-2-yl-1,3-thiazol-2-amine chemical structure, C13H9FN2S2, CAS 5655-38-9
N-(2-Fluorophenyl)-4-thiophen-2-yl-1,3-thiazol-2-amine
CAS 5655-38-9C13H9FN2S2
3-(4-Thiophen-2-yl-thiazol-2-ylamino)-benzoic acid chemical structure, C14H10N2O2S2, CAS 103755-01-7
3-(4-Thiophen-2-yl-thiazol-2-ylamino)-benzoic acid
CAS 103755-01-7C14H10N2O2S2
N-(4-Chlorophenyl)-4-(thiophen-2-yl)-1,3-thiazol-2-amine chemical structure, C13H9ClN2S2, CAS 99514-32-6
N-(4-Chlorophenyl)-4-(thiophen-2-yl)-1,3-thiazol-2-amine
CAS 99514-32-6C13H9ClN2S2
N-Phenyl-4-thiophen-2-yl-1,3-thiazol-2-amine chemical structure, C13H10N2S2, CAS 28989-51-7
N-Phenyl-4-thiophen-2-yl-1,3-thiazol-2-amine
CAS 28989-51-7C13H10N2S2
(2-Methoxyphenyl)-[4-(2-thienyl)thiazol-2-yl]amine chemical structure, C14H12N2OS2, CAS 313243-21-9
(2-Methoxyphenyl)-[4-(2-thienyl)thiazol-2-yl]amine
CAS 313243-21-9C14H12N2OS2
(4-Methoxy-phenyl)-(4-thiophen-2-yl-thiazol-2-yl)-amine chemical structure, C14H12N2OS2, CAS 315702-50-2
(4-Methoxy-phenyl)-(4-thiophen-2-yl-thiazol-2-yl)-amine
CAS 315702-50-2C14H12N2OS2
N-(4-Methylphenyl)-4-thiophen-2-yl-1,3-thiazol-2-amine chemical structure, C14H12N2S2, CAS 107411-07-4
N-(4-Methylphenyl)-4-thiophen-2-yl-1,3-thiazol-2-amine
CAS 107411-07-4C14H12N2S2
N-(3-Methylphenyl)-4-thiophen-2-yl-1,3-thiazol-2-amine chemical structure, C14H12N2S2, CAS 5662-41-9
N-(3-Methylphenyl)-4-thiophen-2-yl-1,3-thiazol-2-amine
CAS 5662-41-9C14H12N2S2
4-(4-(Thiophen-2-yl)thiazol-2-ylamino)-2-hydroxybenzoic acid chemical structure, C14H10N2O3S2, CAS 696628-99-6
4-(4-(Thiophen-2-yl)thiazol-2-ylamino)-2-hydroxybenzoic acid
CAS 696628-99-6C14H10N2O3S2
N-[4-(Thiophen-2-yl)-1,3-thiazol-2-yl]benzene-1,4-diamine chemical structure, C13H11N3S2, CAS 100728-68-5
N-[4-(Thiophen-2-yl)-1,3-thiazol-2-yl]benzene-1,4-diamine
CAS 100728-68-5C13H11N3S2
N-(4-Fluorophenyl)-4-(thiophen-2-yl)-1,3-thiazol-2-amine chemical structure, C13H9FN2S2, CAS 696628-84-9
N-(4-Fluorophenyl)-4-(thiophen-2-yl)-1,3-thiazol-2-amine
CAS 696628-84-9C13H9FN2S2
2-[2-(4-Chloroanilino)-4-thiophen-2-yl-1,3-thiazol-5-yl]acetic acid chemical structure, C15H11ClN2O2S2, CAS 379243-23-9
2-[2-(4-Chloroanilino)-4-thiophen-2-yl-1,3-thiazol-5-yl]acetic acid
CAS 379243-23-9C15H11ClN2O2S2
3-[2-(2,4-Dimethylphenyl)imino-4-thiophen-2-yl-1,3-thiazol-3-yl]propan-1-ol chemical structure, C18H20N2OS2, CAS 905780-89-4
3-[2-(2,4-Dimethylphenyl)imino-4-thiophen-2-yl-1,3-thiazol-3-yl]propan-1-ol
CAS 905780-89-4C18H20N2OS2
(Z)-2-(4-(Thiophen-2-yl)-2-(o-tolylimino)thiazol-3(2H)-yl)ethanol chemical structure, C16H16N2OS2, CAS 905778-23-6
(Z)-2-(4-(Thiophen-2-yl)-2-(o-tolylimino)thiazol-3(2H)-yl)ethanol
CAS 905778-23-6C16H16N2OS2
(Z)-2-(2-((2,4-Dimethylphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol chemical structure, C17H18N2OS2, CAS 915186-69-5
(Z)-2-(2-((2,4-Dimethylphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol
CAS 915186-69-5C17H18N2OS2
(Z)-2-(2-((4-Methoxyphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol chemical structure, C16H16N2O2S2, CAS 928199-33-1
(Z)-2-(2-((4-Methoxyphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol
CAS 928199-33-1C16H16N2O2S2
(Z)-2-(2-((3,4-Dimethylphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol chemical structure, C17H18N2OS2, CAS 915186-71-9
(Z)-2-(2-((3,4-Dimethylphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol
CAS 915186-71-9C17H18N2OS2
(Z)-2-(2-((4-Ethoxyphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol chemical structure, C17H18N2O2S2, CAS 915186-51-5
(Z)-2-(2-((4-Ethoxyphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol
CAS 915186-51-5C17H18N2O2S2
(Z)-2-(2-(Phenylimino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol chemical structure, C15H14N2OS2, CAS 915186-47-9
(Z)-2-(2-(Phenylimino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol
CAS 915186-47-9C15H14N2OS2
(Z)-3-(4-(Thiophen-2-yl)-2-(p-tolylimino)thiazol-3(2H)-yl)propan-1-ol chemical structure, C17H18N2OS2, CAS 928199-36-4
(Z)-3-(4-(Thiophen-2-yl)-2-(p-tolylimino)thiazol-3(2H)-yl)propan-1-ol
CAS 928199-36-4C17H18N2OS2
(Z)-2-(4-(Thiophen-2-yl)-2-(p-tolylimino)thiazol-3(2H)-yl)ethanol chemical structure, C16H16N2OS2, CAS 905778-15-6
(Z)-2-(4-(Thiophen-2-yl)-2-(p-tolylimino)thiazol-3(2H)-yl)ethanol
CAS 905778-15-6C16H16N2OS2
(Z)-2-(2-((2,3-Dimethylphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol chemical structure, C17H18N2OS2, CAS 905778-21-4
(Z)-2-(2-((2,3-Dimethylphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethanol
CAS 905778-21-4C17H18N2OS2
(Z)-3-(2-((2,3-Dimethylphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)propan-1-ol chemical structure, C18H20N2OS2, CAS 905781-28-4
(Z)-3-(2-((2,3-Dimethylphenyl)imino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)propan-1-ol
CAS 905781-28-4C18H20N2OS2