CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 18 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
4
With full pages
4
Scaffold SMILES

O=C(c1ccccc1)C1N=C(c2cccs2)CN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)C1N=C(c2cccs2)CN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

(4-Fluorophenyl)-(3-hydroxy-2,4-dimethyl-1-oxido-5-thiophen-2-yl-4H-imidazol-1-ium-2-yl)methanone chemical structure, C16H15FN2O3S, CAS 433240-33-6
(4-Fluorophenyl)-(3-hydroxy-2,4-dimethyl-1-oxido-5-thiophen-2-yl-4H-imidazol-1-ium-2-yl)methanone
CAS 433240-33-6C16H15FN2O3S
(4-Chlorophenyl)-(3-hydroxy-2,4-dimethyl-1-oxido-5-thiophen-2-yl-4H-imidazol-1-ium-2-yl)methanone chemical structure, C16H15ClN2O3S, CAS 433249-24-2
(4-Chlorophenyl)-(3-hydroxy-2,4-dimethyl-1-oxido-5-thiophen-2-yl-4H-imidazol-1-ium-2-yl)methanone
CAS 433249-24-2C16H15ClN2O3S
(3-Hydroxy-2,4-dimethyl-1-oxido-5-thiophen-2-yl-4H-imidazol-1-ium-2-yl)-(4-methoxyphenyl)methanone chemical structure, C17H18N2O4S, CAS 433250-39-6
(3-Hydroxy-2,4-dimethyl-1-oxido-5-thiophen-2-yl-4H-imidazol-1-ium-2-yl)-(4-methoxyphenyl)methanone
CAS 433250-39-6C17H18N2O4S
(3-Hydroxy-2,4-dimethyl-1-oxido-5-thiophen-2-yl-4H-imidazol-1-ium-2-yl)-(4-methylphenyl)methanone chemical structure, C17H18N2O3S, CAS 433253-76-0
(3-Hydroxy-2,4-dimethyl-1-oxido-5-thiophen-2-yl-4H-imidazol-1-ium-2-yl)-(4-methylphenyl)methanone
CAS 433253-76-0C17H18N2O3S