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Murcko scaffold

Ring system with 3 rings and 17 atoms

36 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
36
With full pages
13
Scaffold SMILES

c1ccc(Nc2nc(-c3cncs3)cs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2nc(-c3cncs3)cs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

N-(5-{2-[(4-Hydroxyphenyl)amino]-1,3-thiazol-4-yl}-4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C15H14N4O2S2, CAS 315705-78-3
N-(5-{2-[(4-Hydroxyphenyl)amino]-1,3-thiazol-4-yl}-4-methyl-1,3-thiazol-2-yl)acetamide
CAS 315705-78-3C15H14N4O2S2
4-(2,4-Dimethyl-1,3-thiazol-5-yl)-N-(2-ethoxyphenyl)-1,3-thiazol-2-amine chemical structure, C16H17N3OS2, CAS 6519-79-5
4-(2,4-Dimethyl-1,3-thiazol-5-yl)-N-(2-ethoxyphenyl)-1,3-thiazol-2-amine
CAS 6519-79-5C16H17N3OS2
N-{4-[(2'-Amino-4'-methyl-4,5'-bi-1,3-thiazol-2-yl)amino]phenyl}acetamide chemical structure, C15H15N5OS2, CAS 315705-04-5
N-{4-[(2'-Amino-4'-methyl-4,5'-bi-1,3-thiazol-2-yl)amino]phenyl}acetamide
CAS 315705-04-5C15H15N5OS2
4-(2,4-Dimethyl-1,3-thiazol-5-yl)-N-(4-methylphenyl)-1,3-thiazol-2-amine chemical structure, C15H15N3S2, CAS 325821-54-3
4-(2,4-Dimethyl-1,3-thiazol-5-yl)-N-(4-methylphenyl)-1,3-thiazol-2-amine
CAS 325821-54-3C15H15N3S2
1-[4-[[4-(2,4-Dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]phenyl]ethanone chemical structure, C16H15N3OS2, CAS 696629-42-2
1-[4-[[4-(2,4-Dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]phenyl]ethanone
CAS 696629-42-2C16H15N3OS2
N-(4-Ethoxyphenyl)-2'-(acetylamino)-4'-methyl-4,5'-bi-1,3-thiazol-2-amine chemical structure, C17H18N4O2S2, CAS 315705-79-4
N-(4-Ethoxyphenyl)-2'-(acetylamino)-4'-methyl-4,5'-bi-1,3-thiazol-2-amine
CAS 315705-79-4C17H18N4O2S2
N-(2-((2-Methoxyphenyl)amino)-4'-methyl-[4,5'-bithiazol]-2'-yl)acetamide chemical structure, C16H16N4O2S2, CAS 315705-75-0
N-(2-((2-Methoxyphenyl)amino)-4'-methyl-[4,5'-bithiazol]-2'-yl)acetamide
CAS 315705-75-0C16H16N4O2S2
N-(5-{2-[(4-Aminophenyl)amino]-1,3-thiazol-4-YL}-4-methyl-1,3-thiazol-2-yl)propanamide chemical structure, C16H17N5OS2, CAS 315704-50-8
N-(5-{2-[(4-Aminophenyl)amino]-1,3-thiazol-4-YL}-4-methyl-1,3-thiazol-2-yl)propanamide
CAS 315704-50-8C16H17N5OS2
N~2~-(5-chloro-2-methoxyphenyl)-4'-methyl-4,5'-bi-1,3-thiazole-2,2'-diamine chemical structure, C14H13ClN4OS2, CAS 333746-75-1
N~2~-(5-chloro-2-methoxyphenyl)-4'-methyl-4,5'-bi-1,3-thiazole-2,2'-diamine
CAS 333746-75-1C14H13ClN4OS2
Mmp-9-IN-7 chemical structure, C16H15ClN4O2S2, CAS 333746-76-2
Mmp-9-IN-7
CAS 333746-76-2C16H15ClN4O2S2
N-(2-((2,5-Dimethoxyphenyl)amino)-4'-methyl-[4,5'-bithiazol]-2'-yl)propionamide chemical structure, C18H20N4O3S2, CAS 412919-82-5
N-(2-((2,5-Dimethoxyphenyl)amino)-4'-methyl-[4,5'-bithiazol]-2'-yl)propionamide
CAS 412919-82-5C18H20N4O3S2
N-[4-Methyl-5-[2-(4-sulfamoylanilino)-1,3-thiazol-4-yl]-1,3-thiazol-2-yl]acetamide chemical structure, C15H15N5O3S3, CAS 307343-36-8
N-[4-Methyl-5-[2-(4-sulfamoylanilino)-1,3-thiazol-4-yl]-1,3-thiazol-2-yl]acetamide
CAS 307343-36-8C15H15N5O3S3
N-[2-[(4-Methoxyphenyl)amino]-4a(2)-methyl[4,5a(2)-bithiazol]-2a(2)-yl]acetamide chemical structure, C16H16N4O2S2, CAS 315705-76-1
N-[2-[(4-Methoxyphenyl)amino]-4a(2)-methyl[4,5a(2)-bithiazol]-2a(2)-yl]acetamide
CAS 315705-76-1C16H16N4O2S2
4-(2'-Amino-4'-methyl-[4,5']bithiazolyl-2-ylamino)-benzenesulfonamide chemical structure, C13H13N5O2S3, CAS 5744-17-2
4-(2'-Amino-4'-methyl-[4,5']bithiazolyl-2-ylamino)-benzenesulfonamide
CAS 5744-17-2C13H13N5O2S3
4-[[4-(2,4-Dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]phenol chemical structure, C14H13N3OS2, CAS 315705-53-4
4-[[4-(2,4-Dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]phenol
CAS 315705-53-4C14H13N3OS2
4'-Methyl-N2-phenyl-[4,5'-bithiazole]-2,2'-diamine chemical structure, C13H12N4S2, CAS 315704-83-7
4'-Methyl-N2-phenyl-[4,5'-bithiazole]-2,2'-diamine
CAS 315704-83-7C13H12N4S2
3-(2'-Amino-4'-methyl-[4,5']bithiazolyl-2-ylamino)-phenol chemical structure, C13H12N4OS2, CAS 5747-94-4
3-(2'-Amino-4'-methyl-[4,5']bithiazolyl-2-ylamino)-phenol
CAS 5747-94-4C13H12N4OS2
4-(2,4-Dimethyl-1,3-thiazol-5-yl)-N-(4-methoxyphenyl)-1,3-thiazol-2-amine chemical structure, C15H15N3OS2, CAS 315705-51-2
4-(2,4-Dimethyl-1,3-thiazol-5-yl)-N-(4-methoxyphenyl)-1,3-thiazol-2-amine
CAS 315705-51-2C15H15N3OS2
N-[5-[2-[4-(Diethylamino)anilino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide, hydrobromide chemical structure, C19H24BrN5OS2, CAS 5933-25-5
N-[5-[2-[4-(Diethylamino)anilino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide, hydrobromide
CAS 5933-25-5C19H24BrN5OS2
N-(5-{2-[(4-Aminophenyl)amino]-1,3-thiazol-4-yl}-4-methyl-1,3-thiazol-2-yl)acetamide hydrobromide chemical structure, C15H16BrN5OS2, CAS 472979-27-4
N-(5-{2-[(4-Aminophenyl)amino]-1,3-thiazol-4-yl}-4-methyl-1,3-thiazol-2-yl)acetamide hydrobromide
CAS 472979-27-4C15H16BrN5OS2
N-(5-{2-[(4-Aminophenyl)amino]-1,3-thiazol-4-YL}-4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C15H15N5OS2, CAS 315705-86-3
N-(5-{2-[(4-Aminophenyl)amino]-1,3-thiazol-4-YL}-4-methyl-1,3-thiazol-2-yl)acetamide
CAS 315705-86-3C15H15N5OS2
N-(5-{2-[(4-Ethoxyphenyl)amino]-1,3-thiazol-4-yl}-4-methyl-1,3-thiazol-2-yl)acetamide hydrobromide chemical structure, C17H19BrN4O2S2, CAS 5935-69-3
N-(5-{2-[(4-Ethoxyphenyl)amino]-1,3-thiazol-4-yl}-4-methyl-1,3-thiazol-2-yl)acetamide hydrobromide
CAS 5935-69-3C17H19BrN4O2S2
N-[5-[2-(4-Ethoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]propanamide, hydrobromide chemical structure, C18H21BrN4O2S2, CAS 5935-73-9
N-[5-[2-(4-Ethoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]propanamide, hydrobromide
CAS 5935-73-9C18H21BrN4O2S2
N-[5-[2-[4-(Dimethylamino)anilino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide, hydrobromide chemical structure, C17H20BrN5OS2, CAS 5935-93-3
N-[5-[2-[4-(Dimethylamino)anilino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide, hydrobromide
CAS 5935-93-3C17H20BrN5OS2