CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
10
With full pages
2
Scaffold SMILES

c1ccc(Cn2ccc(-c3cccs3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cn2ccc(-c3cccs3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

(2E)-3-[1-Benzyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl]prop-2-enoic acid chemical structure, C17H14N2O2S, CAS 956505-56-9
(2E)-3-[1-Benzyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl]prop-2-enoic acid
CAS 956505-56-9C17H14N2O2S
1-Benzyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C15H12N2O2S, CAS 956411-88-4
1-Benzyl-3-(thiophen-2-yl)-1H-pyrazole-4-carboxylic acid
CAS 956411-88-4C15H12N2O2S
1-Benzyl-3-(thiophen-2-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C15H12N2OS, CAS 956438-63-4
1-Benzyl-3-(thiophen-2-yl)-1H-pyrazole-4-carbaldehyde
CAS 956438-63-4C15H12N2OS
3-[1-Benzyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl]-n-butyl-2-cyanoprop-2-enamide chemical structure, C22H22N4OS
3-[1-Benzyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl]-n-butyl-2-cyanoprop-2-enamide
C22H22N4OS
1-Benzyl-3-(thiophen-2-yl)-1H-pyrazol-5-amine chemical structure, C14H13N3S, CAS 222160-56-7
1-Benzyl-3-(thiophen-2-yl)-1H-pyrazol-5-amine
CAS 222160-56-7C14H13N3S
(Z)-3-(1-Benzyl-3-thiophen-2-ylpyrazol-4-yl)-2-cyano-N-(3-methoxypropyl)prop-2-enamide chemical structure, C22H22N4O2S, CAS 1211960-90-5
(Z)-3-(1-Benzyl-3-thiophen-2-ylpyrazol-4-yl)-2-cyano-N-(3-methoxypropyl)prop-2-enamide
CAS 1211960-90-5C22H22N4O2S
(Z)-3-(1-Benzyl-3-thiophen-2-ylpyrazol-4-yl)-2-cyano-N-propan-2-ylprop-2-enamide chemical structure, C21H20N4OS, CAS 1212788-90-3
(Z)-3-(1-Benzyl-3-thiophen-2-ylpyrazol-4-yl)-2-cyano-N-propan-2-ylprop-2-enamide
CAS 1212788-90-3C21H20N4OS
(Z)-3-(1-Benzyl-3-thiophen-2-ylpyrazol-4-yl)-N-butyl-2-cyanoprop-2-enamide chemical structure, C22H22N4OS, CAS 1211958-70-1
(Z)-3-(1-Benzyl-3-thiophen-2-ylpyrazol-4-yl)-N-butyl-2-cyanoprop-2-enamide
CAS 1211958-70-1C22H22N4OS
(Z)-3-(1-Benzyl-3-thiophen-2-ylpyrazol-4-yl)-2-cyano-N-(3-ethoxypropyl)prop-2-enamide chemical structure, C23H24N4O2S, CAS 1241691-18-8
(Z)-3-(1-Benzyl-3-thiophen-2-ylpyrazol-4-yl)-2-cyano-N-(3-ethoxypropyl)prop-2-enamide
CAS 1241691-18-8C23H24N4O2S
5-[1-(Phenylmethyl)-1H-pyrazol-3-yl]-2-thiophenecarboxylic acid chemical structure, C15H12N2O2S, CAS 656226-64-1
5-[1-(Phenylmethyl)-1H-pyrazol-3-yl]-2-thiophenecarboxylic acid
CAS 656226-64-1C15H12N2O2S