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Murcko scaffold

Ring system with 3 rings and 19 atoms

55 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
55
With full pages
12
Scaffold SMILES

O=S(=O)(c1ccccc1)c1coc(-c2ccco2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)c1coc(-c2ccco2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 55 chemicals

2-(2-Furyl)-4-[(4-methylphenyl)sulfonyl]-5-(methylthio)-1,3-oxazole chemical structure, C15H13NO4S2, CAS 686737-66-6
2-(2-Furyl)-4-[(4-methylphenyl)sulfonyl]-5-(methylthio)-1,3-oxazole
CAS 686737-66-6C15H13NO4S2
4-(4-Fluorobenzenesulfonyl)-2-(furan-2-yl)-5-(methylsulfanyl)-1,3-oxazole chemical structure, C14H10FNO4S2, CAS 850928-62-0
4-(4-Fluorobenzenesulfonyl)-2-(furan-2-yl)-5-(methylsulfanyl)-1,3-oxazole
CAS 850928-62-0C14H10FNO4S2
4-(Benzenesulfonyl)-2-(furan-2-yl)-N-methyl-1,3-oxazol-5-amine chemical structure, C14H12N2O4S, CAS 342433-23-2
4-(Benzenesulfonyl)-2-(furan-2-yl)-N-methyl-1,3-oxazol-5-amine
CAS 342433-23-2C14H12N2O4S
4-(4-Chlorophenyl)sulfonyl-5-ethylsulfanyl-2-(furan-2-yl)-1,3-oxazole chemical structure, C15H12ClNO4S2, CAS 686737-99-5
4-(4-Chlorophenyl)sulfonyl-5-ethylsulfanyl-2-(furan-2-yl)-1,3-oxazole
CAS 686737-99-5C15H12ClNO4S2
2-(Furan-2-yl)-N,N-dimethyl-4-tosyloxazol-5-amine chemical structure, C16H16N2O4S, CAS 824417-06-3
2-(Furan-2-yl)-N,N-dimethyl-4-tosyloxazol-5-amine
CAS 824417-06-3C16H16N2O4S
5-(Butylthio)-2-(2-furyl)-4-(phenylsulfonyl)-1,3-oxazole chemical structure, C17H17NO4S2, CAS 850928-46-0
5-(Butylthio)-2-(2-furyl)-4-(phenylsulfonyl)-1,3-oxazole
CAS 850928-46-0C17H17NO4S2
2-({2-(Furan-2-yl)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazol-5-yl}sulfanyl)acetamide chemical structure, C16H14N2O5S2, CAS 686737-64-4
2-({2-(Furan-2-yl)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazol-5-yl}sulfanyl)acetamide
CAS 686737-64-4C16H14N2O5S2
2-(2-Furyl)-5-(isopropylthio)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazole chemical structure, C17H17NO4S2, CAS 686737-68-8
2-(2-Furyl)-5-(isopropylthio)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazole
CAS 686737-68-8C17H17NO4S2
5-(Butylthio)-2-(2-furyl)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazole chemical structure, C18H19NO4S2, CAS 850928-53-9
5-(Butylthio)-2-(2-furyl)-4-[(4-methylphenyl)sulfonyl]-1,3-oxazole
CAS 850928-53-9C18H19NO4S2
4-(4-Chlorophenyl)sulfonyl-2-(furan-2-yl)-5-methylsulfanyl-1,3-oxazole chemical structure, C14H10ClNO4S2, CAS 686737-97-3
4-(4-Chlorophenyl)sulfonyl-2-(furan-2-yl)-5-methylsulfanyl-1,3-oxazole
CAS 686737-97-3C14H10ClNO4S2
4-(4-Bromophenyl)sulfonyl-2-(2-furanyl)-5-(methylthio)oxazole chemical structure, C14H10BrNO4S2, CAS 686738-29-4
4-(4-Bromophenyl)sulfonyl-2-(2-furanyl)-5-(methylthio)oxazole
CAS 686738-29-4C14H10BrNO4S2
4-((4-Bromophenyl)sulfonyl)-5-(ethylthio)-2-(furan-2-yl)oxazole chemical structure, C15H12BrNO4S2, CAS 686738-30-7
4-((4-Bromophenyl)sulfonyl)-5-(ethylthio)-2-(furan-2-yl)oxazole
CAS 686738-30-7C15H12BrNO4S2
4-(4-Bromobenzenesulfonyl)-2-(furan-2-yl)-5-[(2-methylpropyl)sulfanyl]-1,3-oxazole chemical structure, C17H16BrNO4S2, CAS 850928-81-3
4-(4-Bromobenzenesulfonyl)-2-(furan-2-yl)-5-[(2-methylpropyl)sulfanyl]-1,3-oxazole
CAS 850928-81-3C17H16BrNO4S2
4-((4-Fluorophenyl)sulfonyl)-2-(furan-2-yl)-5-(pentylthio)oxazole chemical structure, C18H18FNO4S2, CAS 850928-75-5
4-((4-Fluorophenyl)sulfonyl)-2-(furan-2-yl)-5-(pentylthio)oxazole
CAS 850928-75-5C18H18FNO4S2
4-(Benzenesulfonyl)-N-butyl-2-(furan-2-yl)-1,3-oxazol-5-amine chemical structure, C17H18N2O4S, CAS 823829-28-3
4-(Benzenesulfonyl)-N-butyl-2-(furan-2-yl)-1,3-oxazol-5-amine
CAS 823829-28-3C17H18N2O4S
4-(Benzenesulfonyl)-2-(furan-2-yl)-N-(3-methoxypropyl)-1,3-oxazol-5-amine chemical structure, C17H18N2O5S, CAS 342433-24-3
4-(Benzenesulfonyl)-2-(furan-2-yl)-N-(3-methoxypropyl)-1,3-oxazol-5-amine
CAS 342433-24-3C17H18N2O5S
4-(Benzenesulfonyl)-2-(furan-2-yl)-N-(2-methoxyethyl)-1,3-oxazol-5-amine chemical structure, C16H16N2O5S, CAS 823829-46-5
4-(Benzenesulfonyl)-2-(furan-2-yl)-N-(2-methoxyethyl)-1,3-oxazol-5-amine
CAS 823829-46-5C16H16N2O5S
2-(Furan-2-yl)-N-(3-methoxypropyl)-4-tosyloxazol-5-amine chemical structure, C18H20N2O5S, CAS 823829-62-5
2-(Furan-2-yl)-N-(3-methoxypropyl)-4-tosyloxazol-5-amine
CAS 823829-62-5C18H20N2O5S
2-[[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]acetamide chemical structure, C15H12N2O5S2, CAS 686737-49-5
2-[[4-(Benzenesulfonyl)-2-(furan-2-yl)-1,3-oxazol-5-yl]sulfanyl]acetamide
CAS 686737-49-5C15H12N2O5S2
2-(Furan-2-yl)-5-(isobutylthio)-4-(phenylsulfonyl)oxazole chemical structure, C17H17NO4S2, CAS 850928-50-6
2-(Furan-2-yl)-5-(isobutylthio)-4-(phenylsulfonyl)oxazole
CAS 850928-50-6C17H17NO4S2
2-(Furan-2-yl)-5-(pentylthio)-4-tosyloxazole chemical structure, C19H21NO4S2, CAS 850928-55-1
2-(Furan-2-yl)-5-(pentylthio)-4-tosyloxazole
CAS 850928-55-1C19H21NO4S2
5-(Butylthio)-4-[(4-chlorophenyl)sulfonyl]-2-(2-furyl)-1,3-oxazole chemical structure, C17H16ClNO4S2, CAS 850928-77-7
5-(Butylthio)-4-[(4-chlorophenyl)sulfonyl]-2-(2-furyl)-1,3-oxazole
CAS 850928-77-7C17H16ClNO4S2
4-(4-Chlorobenzenesulfonyl)-2-(furan-2-yl)-5-(pentylsulfanyl)-1,3-oxazole chemical structure, C18H18ClNO4S2, CAS 850928-79-9
4-(4-Chlorobenzenesulfonyl)-2-(furan-2-yl)-5-(pentylsulfanyl)-1,3-oxazole
CAS 850928-79-9C18H18ClNO4S2
4-((4-Bromophenyl)sulfonyl)-5-(butylthio)-2-(furan-2-yl)oxazole chemical structure, C17H16BrNO4S2, CAS 850928-80-2
4-((4-Bromophenyl)sulfonyl)-5-(butylthio)-2-(furan-2-yl)oxazole
CAS 850928-80-2C17H16BrNO4S2