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Murcko scaffold

1-[(3-Thien-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperazine scaffold

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
5
With full pages
2
Scaffold SMILES

c1csc(-c2noc(CN3CCNCC3)n2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-[(3-Thien-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperazine page
Murcko scaffold c1csc(-c2noc(CN3CCNCC3)n2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

Ethyl 4-{[3-(2-thienyl)-1,2,4-oxadiazol-5-yl]methyl}piperazine-1-carboxylate chemical structure, C14H18N4O3S, CAS 875660-12-1
Ethyl 4-{[3-(2-thienyl)-1,2,4-oxadiazol-5-yl]methyl}piperazine-1-carboxylate
CAS 875660-12-1C14H18N4O3S
1-[(3-Thien-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperazine chemical structure, C11H14N4OS, CAS 923789-81-5
1-[(3-Thien-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperazine
CAS 923789-81-5C11H14N4OS
1-(Prop-2-yn-1-yl)-4-{[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperazine chemical structure, C14H16N4OS, CAS 1311674-95-9
1-(Prop-2-yn-1-yl)-4-{[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperazine
CAS 1311674-95-9C14H16N4OS
1-{1-[3-(Thiophen-2-yl)-1,2,4-oxadiazol-5-yl]ethyl}piperazine chemical structure, C12H16N4OS, CAS 1285080-85-4
1-{1-[3-(Thiophen-2-yl)-1,2,4-oxadiazol-5-yl]ethyl}piperazine
CAS 1285080-85-4C12H16N4OS
1-{[3-(Thiophen-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperazine hydrochloride chemical structure, C11H15ClN4OS, CAS 1803597-91-2
1-{[3-(Thiophen-2-yl)-1,2,4-oxadiazol-5-yl]methyl}piperazine hydrochloride
CAS 1803597-91-2C11H15ClN4OS