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Murcko scaffold

2-(2-Naphthyloxy)-N-phenylacetamide scaffold

124 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
124
With full pages
4
Scaffold SMILES

O=C(COc1ccc2ccccc2c1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(2-Naphthyloxy)-N-phenylacetamide page
Murcko scaffold O=C(COc1ccc2ccccc2c1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 124 chemicals

Naproanilide chemical structure, C19H17NO2, CAS 52570-16-8
Naproanilide
CAS 52570-16-8C19H17NO2
2-Diethylaminoethyl 4-[(2-naphthalen-2-yloxyacetyl)amino]benzoate chemical structure, C25H28N2O4, CAS 72836-56-7
2-Diethylaminoethyl 4-[(2-naphthalen-2-yloxyacetyl)amino]benzoate
CAS 72836-56-7C25H28N2O4
N-(2-Fluoro-5-nitrophenyl)-2-(2-naphthyloxy)acetamide chemical structure, C18H13FN2O4, CAS 315669-87-5
N-(2-Fluoro-5-nitrophenyl)-2-(2-naphthyloxy)acetamide
CAS 315669-87-5C18H13FN2O4
N-(2-Methyl-3-nitrophenyl)-2-(2-naphthyloxy)acetamide chemical structure, C19H16N2O4, CAS 315670-27-0
N-(2-Methyl-3-nitrophenyl)-2-(2-naphthyloxy)acetamide
CAS 315670-27-0C19H16N2O4
N-(3-Fluoro-4-methylphenyl)-2-(2-naphthyloxy)acetamide chemical structure, C19H16FNO2, CAS 356086-55-0
N-(3-Fluoro-4-methylphenyl)-2-(2-naphthyloxy)acetamide
CAS 356086-55-0C19H16FNO2
N-{4-[Acetyl(methyl)amino]phenyl}-2-(2-naphthyloxy)acetamide chemical structure, C21H20N2O3, CAS 315670-48-5
N-{4-[Acetyl(methyl)amino]phenyl}-2-(2-naphthyloxy)acetamide
CAS 315670-48-5C21H20N2O3
N-(2-Cyanophenyl)-2-(2-naphthyloxy)acetamide chemical structure, C19H14N2O2, CAS 327071-27-2
N-(2-Cyanophenyl)-2-(2-naphthyloxy)acetamide
CAS 327071-27-2C19H14N2O2
2-(2-Naphthyloxy)-N-phenylacetamide chemical structure, C18H15NO2, CAS 78162-22-8
2-(2-Naphthyloxy)-N-phenylacetamide
CAS 78162-22-8C18H15NO2
N-(4-Hydroxyphenyl)-2-naphthalen-2-yloxyacetamide chemical structure, C18H15NO3, CAS 434292-52-1
N-(4-Hydroxyphenyl)-2-naphthalen-2-yloxyacetamide
CAS 434292-52-1C18H15NO3
N-(3-{[(Naphthalen-2-yloxy)acetyl]amino}phenyl)propanamide chemical structure, C21H20N2O3, CAS 432001-47-3
N-(3-{[(Naphthalen-2-yloxy)acetyl]amino}phenyl)propanamide
CAS 432001-47-3C21H20N2O3
N-(3-Methylphenyl)-2-(2-naphthyloxy)acetamide chemical structure, C19H17NO2, CAS 355368-51-3
N-(3-Methylphenyl)-2-(2-naphthyloxy)acetamide
CAS 355368-51-3C19H17NO2
N-(3-Chloro-4-methylphenyl)-2-(2-naphthyloxy)acetamide chemical structure, C19H16ClNO2, CAS 340974-44-9
N-(3-Chloro-4-methylphenyl)-2-(2-naphthyloxy)acetamide
CAS 340974-44-9C19H16ClNO2
N-(3-Chlorophenyl)-2-(2-naphthyloxy)acetamide chemical structure, C18H14ClNO2, CAS 397281-60-6
N-(3-Chlorophenyl)-2-(2-naphthyloxy)acetamide
CAS 397281-60-6C18H14ClNO2
N-(4-Chlorophenyl)-2-naphthalen-2-yloxyacetamide chemical structure, C18H14ClNO2, CAS 349644-20-8
N-(4-Chlorophenyl)-2-naphthalen-2-yloxyacetamide
CAS 349644-20-8C18H14ClNO2
N-(3,4-Dichlorophenyl)-2-(2-naphthyloxy)acetamide chemical structure, C18H13Cl2NO2, CAS 349644-33-3
N-(3,4-Dichlorophenyl)-2-(2-naphthyloxy)acetamide
CAS 349644-33-3C18H13Cl2NO2
N-(2,5-Dimethoxyphenyl)-2-(naphthalen-2-yloxy)acetamide chemical structure, C20H19NO4, CAS 349644-40-2
N-(2,5-Dimethoxyphenyl)-2-(naphthalen-2-yloxy)acetamide
CAS 349644-40-2C20H19NO4
N-(2,5-Dimethylphenyl)-2-(2-naphthyloxy)acetamide chemical structure, C20H19NO2, CAS 349644-37-7
N-(2,5-Dimethylphenyl)-2-(2-naphthyloxy)acetamide
CAS 349644-37-7C20H19NO2
N-(2-Fluorophenyl)-2-naphthalen-2-yloxyacetamide chemical structure, C18H14FNO2, CAS 544665-33-0
N-(2-Fluorophenyl)-2-naphthalen-2-yloxyacetamide
CAS 544665-33-0C18H14FNO2
N-(2-Isopropylphenyl)-2-(2-naphthyloxy)acetamide chemical structure, C21H21NO2, CAS 425374-05-6
N-(2-Isopropylphenyl)-2-(2-naphthyloxy)acetamide
CAS 425374-05-6C21H21NO2
N-(2,4-Dimethoxyphenyl)-2-(2-naphthyloxy)acetamide chemical structure, C20H19NO4, CAS 425374-87-4
N-(2,4-Dimethoxyphenyl)-2-(2-naphthyloxy)acetamide
CAS 425374-87-4C20H19NO4
N-(5-Chloro-2-methylphenyl)-2-(2-naphthyloxy)acetamide chemical structure, C19H16ClNO2, CAS 425400-29-9
N-(5-Chloro-2-methylphenyl)-2-(2-naphthyloxy)acetamide
CAS 425400-29-9C19H16ClNO2
N-Methyl-2-naphthalen-2-yloxy-N-phenylacetamide chemical structure, C19H17NO2, CAS 744263-78-3
N-Methyl-2-naphthalen-2-yloxy-N-phenylacetamide
CAS 744263-78-3C19H17NO2
N-(4-Isopropylphenyl)-2-(2-naphthyloxy)acetamide chemical structure, C21H21NO2, CAS 425401-84-9
N-(4-Isopropylphenyl)-2-(2-naphthyloxy)acetamide
CAS 425401-84-9C21H21NO2
N-(3,4-Dimethoxyphenyl)-2-(2-naphthyloxy)acetamide chemical structure, C20H19NO4, CAS 461395-45-9
N-(3,4-Dimethoxyphenyl)-2-(2-naphthyloxy)acetamide
CAS 461395-45-9C20H19NO4