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Murcko scaffold

Ring system with 2 rings and 21 atoms

7 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
21
Chemicals
7
With full pages
2
Scaffold SMILES

O=C(CCc1ccccc1)NCC(=O)C1CC(=O)NC1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCc1ccccc1)NCC(=O)C1CC(=O)NC1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Andrimid chemical structure, C27H33N3O5, CAS 108868-95-7
Andrimid
CAS 108868-95-7C27H33N3O5
Moiramide B chemical structure, C25H31N3O5, CAS 155233-31-1
Moiramide B
CAS 155233-31-1C25H31N3O5
(S)-3-Amino-N-((S)-3-methyl-1-((3R,4S)-4-methyl-2,5-dioxopyrrolidin-3-yl)-1-oxobutan-2-yl)-3-phenylpropanamide chemical structure, C19H25N3O4, CAS 792903-64-1
(S)-3-Amino-N-((S)-3-methyl-1-((3R,4S)-4-methyl-2,5-dioxopyrrolidin-3-yl)-1-oxobutan-2-yl)-3-phenylpropanamide
CAS 792903-64-1C19H25N3O4
(2E,4E)-Hexa-2,4-dienoic acid {(S)-2-[(S)-2-methyl-1-((3R,4S)-4-methyl-2,5-dioxo-pyrrolidine-3-carbonyl)-propylcarbamoyl]-1-phenyl-ethyl}-amide chemical structure, C25H31N3O5
(2E,4E)-Hexa-2,4-dienoic acid {(S)-2-[(S)-2-methyl-1-((3R,4S)-4-methyl-2,5-dioxo-pyrrolidine-3-carbonyl)-propylcarbamoyl]-1-phenyl-ethyl}-amide
C25H31N3O5
(2Z)-N-[(1R)-3-[[3-Methyl-1-[(3S,4S)-4-methyl-2,5-dioxopyrrolidin-3-yl]-1-oxobutan-2-yl]amino]-3-oxo-1-phenylpropyl]hexa-2,4-dienamide chemical structure, C25H31N3O5
(2Z)-N-[(1R)-3-[[3-Methyl-1-[(3S,4S)-4-methyl-2,5-dioxopyrrolidin-3-yl]-1-oxobutan-2-yl]amino]-3-oxo-1-phenylpropyl]hexa-2,4-dienamide
C25H31N3O5
N-[(1R)-3-[[3-Methyl-1-[(3S,4S)-4-methyl-2,5-dioxopyrrolidin-3-yl]-1-oxobutan-2-yl]amino]-3-oxo-1-phenylpropyl]hexa-2,4-dienamide chemical structure, C25H31N3O5
N-[(1R)-3-[[3-Methyl-1-[(3S,4S)-4-methyl-2,5-dioxopyrrolidin-3-yl]-1-oxobutan-2-yl]amino]-3-oxo-1-phenylpropyl]hexa-2,4-dienamide
C25H31N3O5
(2E,4E)-N-[(1R)-3-[[3-Methyl-1-[(3S,4S)-4-methyl-2,5-dioxopyrrolidin-3-yl]-1-oxobutan-2-yl]amino]-3-oxo-1-phenylpropyl]hexa-2,4-dienamide chemical structure, C25H31N3O5
(2E,4E)-N-[(1R)-3-[[3-Methyl-1-[(3S,4S)-4-methyl-2,5-dioxopyrrolidin-3-yl]-1-oxobutan-2-yl]amino]-3-oxo-1-phenylpropyl]hexa-2,4-dienamide
C25H31N3O5