Murcko scaffold
5-Phenylpyrazolo[1,5-A]pyrimidin-7-ol scaffold
52 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 16
- Chemicals
- 52
- With full pages
- 3
Scaffold SMILES
O=c1cc(-c2ccccc2)nc2cc[nH]n12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1cc(-c2ccccc2)nc2cc[nH]n12](/scaffold/KUCBMSUTIBMISH-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 52 chemicals
![Ethyl 7-hydroxy-5-phenylpyrazolo[1,5-A]pyrimidine-3-carboxylate chemical structure, C15H13N3O3, CAS 77493-87-9](/s/RIFVPBRHBFOIOU-UHFFFAOYSA-N.svg)
Ethyl 7-hydroxy-5-phenylpyrazolo[1,5-A]pyrimidine-3-carboxylate
CAS 77493-87-9C15H13N3O3
![Pyrazolo[1,5-a]pyrimidin-7(4H)-one, 2-methyl-5-phenyl- chemical structure, C13H11N3O, CAS 107625-17-2](/s/HHROHNILKCJWQG-UHFFFAOYSA-N.svg)
Pyrazolo[1,5-a]pyrimidin-7(4H)-one, 2-methyl-5-phenyl-
CAS 107625-17-2C13H11N3O
![Pyrazolo[1,5-a]pyrimidin-7(1H)-one, 1-methyl-5-phenyl- chemical structure, C13H11N3O, CAS 64748-43-2](/s/GDFXDJCUSZKHKI-UHFFFAOYSA-N.svg)
Pyrazolo[1,5-a]pyrimidin-7(1H)-one, 1-methyl-5-phenyl-
CAS 64748-43-2C13H11N3O
![1-Methyl-5-(p-chlorophenyl)-pyrazolo[1,5-a]pyrimidin-7(1H)one chemical structure, C13H10ClN3O, CAS 64748-58-9](/s/XAOUKVJFRQIVRR-UHFFFAOYSA-N.svg)
1-Methyl-5-(p-chlorophenyl)-pyrazolo[1,5-a]pyrimidin-7(1H)one
CAS 64748-58-9C13H10ClN3O
![5-Phenylpyrazolo[1,5-A]pyrimidin-7-ol chemical structure, C12H9N3O, CAS 874764-64-4](/s/KUCBMSUTIBMISH-UHFFFAOYSA-N.svg)
5-Phenylpyrazolo[1,5-A]pyrimidin-7-ol
CAS 874764-64-4C12H9N3O
![5-(4-Chloro-phenyl)-pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C12H8ClN3O, CAS 99898-81-4](/s/WKMKVROWHGQDHL-UHFFFAOYSA-N.svg)
5-(4-Chloro-phenyl)-pyrazolo[1,5-a]pyrimidin-7-ol
CAS 99898-81-4C12H8ClN3O
![5-(4-Nitrophenyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C12H8N4O3, CAS 99898-82-5](/s/IZVWLFCTSNHPCA-UHFFFAOYSA-N.svg)
5-(4-Nitrophenyl)pyrazolo[1,5-a]pyrimidin-7-ol
CAS 99898-82-5C12H8N4O3
![3-Methyl-5-phenyl-4H,7H-pyrazolo[1,5-a]pyrimidin-7-one chemical structure, C13H11N3O, CAS 1918008-18-0](/s/XUCWHPYQGRKZTB-UHFFFAOYSA-N.svg)
3-Methyl-5-phenyl-4H,7H-pyrazolo[1,5-a]pyrimidin-7-one
CAS 1918008-18-0C13H11N3O
![2-Amino-3-nitro-5-phenylpyrazolo[1,5-a]pyrimidin-7(1H)-one chemical structure, C12H9N5O3, CAS 201221-99-0](/s/MHLZJFZYGIIIQD-UHFFFAOYSA-N.svg)
2-Amino-3-nitro-5-phenylpyrazolo[1,5-a]pyrimidin-7(1H)-one
CAS 201221-99-0C12H9N5O3
![7-Oxo-5-phenyl-4H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid chemical structure, C13H9N3O3, CAS 632365-48-1](/s/VYBQMSCDSUNRQL-UHFFFAOYSA-N.svg)
7-Oxo-5-phenyl-4H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS 632365-48-1C13H9N3O3
![5-(2-Chlorophenyl)-7-oxo-4H-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C13H8ClN3O3, CAS 632365-49-2](/s/RHHDNNAZUXUZOL-UHFFFAOYSA-N.svg)
5-(2-Chlorophenyl)-7-oxo-4H-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS 632365-49-2C13H8ClN3O3
![7-Hydroxy-n-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide chemical structure, C14H12N4O2, CAS 934827-17-5](/s/OVARIJVUYPVWTQ-UHFFFAOYSA-N.svg)
7-Hydroxy-n-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CAS 934827-17-5C14H12N4O2
![7-Hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C13H8N4O, CAS 1429250-98-5](/s/KYNMRURAEWFSBX-UHFFFAOYSA-N.svg)
7-Hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS 1429250-98-5C13H8N4O
![5-(2,3-Dichlorophenyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one chemical structure, C12H7Cl2N3O, CAS 672325-07-4](/s/IJJLSMLJMXURGF-UHFFFAOYSA-N.svg)
5-(2,3-Dichlorophenyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
CAS 672325-07-4C12H7Cl2N3O
![5-(2-Fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C12H8FN3O, CAS 672325-00-7](/s/YXGIGALOMVQYMT-UHFFFAOYSA-N.svg)
5-(2-Fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-ol
CAS 672325-00-7C12H8FN3O
![5-(2-Methoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C13H11N3O2, CAS 672325-05-2](/s/JLCQIRQKLAVTTF-UHFFFAOYSA-N.svg)
5-(2-Methoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-ol
CAS 672325-05-2C13H11N3O2
![7-Hydroxy-5-(alpha,alpha,alpha-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine chemical structure, C13H8F3N3O, CAS 72851-85-5](/s/BACUPTMZGGZGMP-UHFFFAOYSA-N.svg)
7-Hydroxy-5-(alpha,alpha,alpha-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine
CAS 72851-85-5C13H8F3N3O
![5-(o-Tolyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C13H11N3O, CAS 672325-13-2](/s/REUNMVBEGNIXIE-UHFFFAOYSA-N.svg)
5-(o-Tolyl)pyrazolo[1,5-a]pyrimidin-7-ol
CAS 672325-13-2C13H11N3O
![3-Isopropyl-5-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C15H15N3O, CAS 2247954-99-8](/s/JAICIFRPNXNMIM-UHFFFAOYSA-N.svg)
3-Isopropyl-5-phenylpyrazolo[1,5-a]pyrimidin-7(4H)-one
CAS 2247954-99-8C15H15N3O
![5-(2,4-Dichlorophenyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C12H7Cl2N3O, CAS 672323-21-6](/s/DCOOLBHGVBCSAG-UHFFFAOYSA-N.svg)
5-(2,4-Dichlorophenyl)pyrazolo[1,5-a]pyrimidin-7-ol
CAS 672323-21-6C12H7Cl2N3O
![5-(2-Bromophenyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C12H8BrN3O, CAS 672325-15-4](/s/CICXMABCRYREFV-UHFFFAOYSA-N.svg)
5-(2-Bromophenyl)pyrazolo[1,5-a]pyrimidin-7-ol
CAS 672325-15-4C12H8BrN3O
![5-[4-(tert-Butyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C16H17N3O, CAS 672323-17-0](/s/ALALZNNQDWLLIE-UHFFFAOYSA-N.svg)
5-[4-(tert-Butyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-ol
CAS 672323-17-0C16H17N3O
![5-(3-Bromophenyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C12H8BrN3O, CAS 2826770-34-5](/s/LSQZGYYEQBJZKR-UHFFFAOYSA-N.svg)
5-(3-Bromophenyl)pyrazolo[1,5-a]pyrimidin-7-ol
CAS 2826770-34-5C12H8BrN3O
![5-(4-Bromophenyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C12H8BrN3O, CAS 2088507-08-6](/s/YDDGYAMTGBNGBY-UHFFFAOYSA-N.svg)
5-(4-Bromophenyl)pyrazolo[1,5-a]pyrimidin-7-ol
CAS 2088507-08-6C12H8BrN3O
- 5-(4-Iodophenyl)pyrazolo[1,5-a]pyrimidin-7-ol2088526-35-4C12H8IN3O
- 5-(3-Nitrophenyl)pyrazolo[1,5-a]pyrimidin-7-ol940284-33-3C12H8N4O3
- 7-Oxo-5-phenyl-4,7-dihydro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid ethyl ester632365-60-7C15H13N3O3
- 5-(2-Chloro-phenyl)-7-oxo-4,7-dihydro-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester632365-62-9C15H12ClN3O3
- Ethyl 5-(4-chlorophenyl)-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-2-carboxylate632365-51-6C15H12ClN3O3
- Ethyl 5-(4-chloro-phenyl)-7-hydroxy-pyrazolo[1,5-a]pyrimidine-3-carboxylate871571-79-8C15H12ClN3O3
- 5-(4-Chlorophenyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylic acid871573-69-2C13H8ClN3O3
- 7-Oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carboxylic acid632365-47-0C13H9N3O3
- 1 suppliers6-Isopropyl-7-oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile1628208-23-0C16H14N4O
- 5-(m-Tolyl)pyrazolo[1,5-a]pyrimidin-7-ol189018-01-7C13H11N3O
- 5-(3,4-Dichlorophenyl)-7-oxo-4H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide1607024-98-5C13H8Cl2N4O2
- 6-Ethyl-7-oxo-5-o-tolyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile1628214-07-2C16H14N4O
- 3-Cyano-4,7-dihydro-7-oxo-5-phenyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid methyl ester1628210-17-2C15H10N4O3
- 6-Isopropyl-7-oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carboxamide1956332-40-3C16H16N4O2
- 5-(4-Fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-ol2832422-34-9C12H8FN3O
- 7-Oxo-5-phenyl-6-propyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile2514279-11-7C16H14N4O
- 1 suppliersCPI-455 hydrochloride2095432-28-1C16H15ClN4O
- 5-Phenyl-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxamidoxime1965308-70-6C13H11N5O2
- 7-Hydroxy-N-(2-hydroxyethyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide2378168-40-0C15H14N4O3
- Ethyl 5-(4-Bromophenyl)-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carboxylate2394830-27-2C15H12BrN3O3
- 5-(4-Methoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-ol2485043-36-3C13H11N3O2
- 3-Bromo-6-isopropyl-5-phenyl-4H-pyrazolo[1,5-A]pyrimidin-7-one2587155-33-5C15H14BrN3O
- Brca2-rad51-IN-12830213-53-9C13H7BrF3N3O
- 5-(2-Iodophenyl)pyrazolo[1,5-a]pyrimidin-7-ol2840072-32-2C12H8IN3O
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