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Murcko scaffold

Morpholino(4-(phenylsulfonyl)piperazin-1-yl)methanone scaffold

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
9
With full pages
6
Scaffold SMILES

O=C(N1CCOCC1)N1CCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Morpholino(4-(phenylsulfonyl)piperazin-1-yl)methanone page
Murcko scaffold O=C(N1CCOCC1)N1CCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

Morpholin-4-yl-[4-(toluene-4-sulfonyl)-piperazin-1-yl]-methanone chemical structure, C16H23N3O4S, CAS 510734-46-0
Morpholin-4-yl-[4-(toluene-4-sulfonyl)-piperazin-1-yl]-methanone
CAS 510734-46-0C16H23N3O4S
[4-(2,4-Dimethyl-benzenesulfonyl)-piperazin-1-yl]-morpholin-4-yl-methanone chemical structure, C17H25N3O4S, CAS 501104-61-6
[4-(2,4-Dimethyl-benzenesulfonyl)-piperazin-1-yl]-morpholin-4-yl-methanone
CAS 501104-61-6C17H25N3O4S
Morpholin-4-yl-[4-(2,4,6-trimethyl-benzenesulfonyl)-piperazin-1-yl]-methanone chemical structure, C18H27N3O4S, CAS 701968-54-9
Morpholin-4-yl-[4-(2,4,6-trimethyl-benzenesulfonyl)-piperazin-1-yl]-methanone
CAS 701968-54-9C18H27N3O4S
(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)(morpholino)methanone chemical structure, C15H20ClN3O4S, CAS 692762-04-2
(4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)(morpholino)methanone
CAS 692762-04-2C15H20ClN3O4S
[4-(4-Fluoro-benzenesulfonyl)-piperazin-1-yl]-morpholin-4-yl-methanone chemical structure, C15H20FN3O4S, CAS 712345-23-8
[4-(4-Fluoro-benzenesulfonyl)-piperazin-1-yl]-morpholin-4-yl-methanone
CAS 712345-23-8C15H20FN3O4S
N-(4-{[4-(4-Morpholinylcarbonyl)-1-piperazinyl]sulfonyl}phenyl)acetamide chemical structure, C17H24N4O5S, CAS 667891-17-0
N-(4-{[4-(4-Morpholinylcarbonyl)-1-piperazinyl]sulfonyl}phenyl)acetamide
CAS 667891-17-0C17H24N4O5S
[4-(3,4-Dimethyl-benzenesulfonyl)-piperazin-1-yl]-morpholin-4-yl-methanone chemical structure, C17H25N3O4S, CAS 713096-44-7
[4-(3,4-Dimethyl-benzenesulfonyl)-piperazin-1-yl]-morpholin-4-yl-methanone
CAS 713096-44-7C17H25N3O4S
Morpholino(4-(phenylsulfonyl)piperazin-1-yl)methanone chemical structure, C15H21N3O4S, CAS 510734-48-2
Morpholino(4-(phenylsulfonyl)piperazin-1-yl)methanone
CAS 510734-48-2C15H21N3O4S
Morpholino(4-((3-nitrophenyl)sulfonyl)piperazin-1-yl)methanone chemical structure, C15H20N4O6S, CAS 694467-66-8
Morpholino(4-((3-nitrophenyl)sulfonyl)piperazin-1-yl)methanone
CAS 694467-66-8C15H20N4O6S