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Murcko scaffold

N-Phenyl-4-(pyrimidin-2-yl)piperazine-1-carboxamide scaffold

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
16
With full pages
3
Scaffold SMILES

O=C(Nc1ccccc1)N1CCN(c2ncccn2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-4-(pyrimidin-2-yl)piperazine-1-carboxamide page
Murcko scaffold O=C(Nc1ccccc1)N1CCN(c2ncccn2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

N-Phenyl-4-(pyrimidin-2-yl)piperazine-1-carboxamide chemical structure, C15H17N5O, CAS 717875-78-0
N-Phenyl-4-(pyrimidin-2-yl)piperazine-1-carboxamide
CAS 717875-78-0C15H17N5O
N-(2-Methoxyphenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide chemical structure, C16H19N5O2, CAS 606118-03-0
N-(2-Methoxyphenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide
CAS 606118-03-0C16H19N5O2
N-(4-Chlorophenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide chemical structure, C15H16ClN5O, CAS 831193-66-9
N-(4-Chlorophenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide
CAS 831193-66-9C15H16ClN5O
N-(4-Bromo-2-chlorophenyl)-4-pyrimidin-2-ylpiperazine-1-carboxamide chemical structure, C15H15BrClN5O, CAS 701933-94-0
N-(4-Bromo-2-chlorophenyl)-4-pyrimidin-2-ylpiperazine-1-carboxamide
CAS 701933-94-0C15H15BrClN5O
N-(2,4-Dimethylphenyl)-4-pyrimidin-2-ylpiperazine-1-carboxamide chemical structure, C17H21N5O, CAS 897331-97-4
N-(2,4-Dimethylphenyl)-4-pyrimidin-2-ylpiperazine-1-carboxamide
CAS 897331-97-4C17H21N5O
N-(3-Methoxyphenyl)-4-pyrimidin-2-ylpiperazine-1-carboxamide chemical structure, C16H19N5O2, CAS 896573-46-9
N-(3-Methoxyphenyl)-4-pyrimidin-2-ylpiperazine-1-carboxamide
CAS 896573-46-9C16H19N5O2
N-(4-Fluorophenyl)[4-(5-methylpyrimidin-2-yl)piperazinyl]carboxamide chemical structure, C16H18FN5O, CAS 930076-13-4
N-(4-Fluorophenyl)[4-(5-methylpyrimidin-2-yl)piperazinyl]carboxamide
CAS 930076-13-4C16H18FN5O
N-(3-Methylphenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide chemical structure, C16H19N5O, CAS 890578-16-2
N-(3-Methylphenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide
CAS 890578-16-2C16H19N5O
N-(2-Ethylphenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide chemical structure, C17H21N5O, CAS 897331-93-0
N-(2-Ethylphenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide
CAS 897331-93-0C17H21N5O
N-(4-Acetylphenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide chemical structure, C17H19N5O2, CAS 847477-52-5
N-(4-Acetylphenyl)-4-(pyrimidin-2-yl)piperazine-1-carboxamide
CAS 847477-52-5C17H19N5O2
N-(4-Chlorophenyl)-4-(4-(ethylamino)-6-methylpyrimidin-2-yl)piperazine-1-carboxamide chemical structure, C18H23ClN6O, CAS 923165-46-2
N-(4-Chlorophenyl)-4-(4-(ethylamino)-6-methylpyrimidin-2-yl)piperazine-1-carboxamide
CAS 923165-46-2C18H23ClN6O
4-[4-(Ethylamino)-6-methylpyrimidin-2-yl]-N-(4-fluorophenyl)piperazine-1-carboxamide chemical structure, C18H23FN6O, CAS 923678-16-4
4-[4-(Ethylamino)-6-methylpyrimidin-2-yl]-N-(4-fluorophenyl)piperazine-1-carboxamide
CAS 923678-16-4C18H23FN6O
4-(4-(Dimethylamino)-6-methylpyrimidin-2-yl)-N-(4-methoxyphenyl)piperazine-1-carboxamide chemical structure, C19H26N6O2, CAS 923173-04-0
4-(4-(Dimethylamino)-6-methylpyrimidin-2-yl)-N-(4-methoxyphenyl)piperazine-1-carboxamide
CAS 923173-04-0C19H26N6O2
N-(4-Chlorophenyl)-4-(4-(dimethylamino)-6-methylpyrimidin-2-yl)piperazine-1-carboxamide chemical structure, C18H23ClN6O, CAS 946282-01-5
N-(4-Chlorophenyl)-4-(4-(dimethylamino)-6-methylpyrimidin-2-yl)piperazine-1-carboxamide
CAS 946282-01-5C18H23ClN6O
N-(5-Fluoro-2-methylphenyl)-4-(2-pyrimidinyl)-1-piperazinecarboxamide chemical structure, C16H18FN5O, CAS 1177924-53-6
N-(5-Fluoro-2-methylphenyl)-4-(2-pyrimidinyl)-1-piperazinecarboxamide
CAS 1177924-53-6C16H18FN5O
4-({[4-(Pyrimidin-2-yl)piperazin-1-yl]carbonyl}amino)benzoic acid chemical structure, C16H17N5O3, CAS 1374526-79-0
4-({[4-(Pyrimidin-2-yl)piperazin-1-yl]carbonyl}amino)benzoic acid
CAS 1374526-79-0C16H17N5O3