Murcko scaffold
6-Oxa-2-azaspiro(3.5)nonane scaffold
45 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 45
- With full pages
- 6
Scaffold SMILES
C1COCC2(C1)CNC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 45 of 45 chemicals
6-Oxa-2-azaspiro(3.5)nonane
CAS 1214875-08-7C7H13NO
![6-Oxa-2-azaspiro[3.5]nonane oxalate chemical structure, C9H15NO5, CAS 1389264-15-6](/s/IFPKYQWHMJLGFF-UHFFFAOYSA-N.svg)
6-Oxa-2-azaspiro[3.5]nonane oxalate
CAS 1389264-15-6C9H15NO5
6-Oxa-2-azaspiro(3.5)nonane hydrochloride
CAS 1359656-29-3C7H14ClNO
![6-Oxa-2-azaspiro[3.5]nonane hemioxalate chemical structure, C16H28N2O6, CAS 1523606-37-2](/s/FYKVYXCJDKVWQV-UHFFFAOYSA-N.svg)
6-Oxa-2-azaspiro[3.5]nonane hemioxalate
CAS 1523606-37-2C16H28N2O6
![tert-Butyl 6-oxa-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C12H21NO3, CAS 1934865-39-0](/s/RUZGMAAQHKFYLJ-UHFFFAOYSA-N.svg)
tert-Butyl 6-oxa-2-azaspiro[3.5]nonane-2-carboxylate
CAS 1934865-39-0C12H21NO3
![tert-Butyl 7-(aminomethyl)-6-oxa-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C13H24N2O3, CAS 1251012-44-8](/s/LSINTCYZJFPPPD-UHFFFAOYSA-N.svg)
tert-Butyl 7-(aminomethyl)-6-oxa-2-azaspiro[3.5]nonane-2-carboxylate
CAS 1251012-44-8C13H24N2O3
![1-(6-Oxa-2-azaspiro[3.5]nonan-2-yl)prop-2-en-1-one chemical structure, C10H15NO2, CAS 2190141-20-7](/s/VPUAIUSQGOULFK-UHFFFAOYSA-N.svg)
1-(6-Oxa-2-azaspiro[3.5]nonan-2-yl)prop-2-en-1-one
CAS 2190141-20-7C10H15NO2
![tert-Butyl 7-(iodomethyl)-6-oxa-2-azaspiro[3.5]nonane-2-carboxylate chemical structure, C13H22INO3, CAS 2385239-07-4](/s/RBYYKRMONJTHNW-UHFFFAOYSA-N.svg)
tert-Butyl 7-(iodomethyl)-6-oxa-2-azaspiro[3.5]nonane-2-carboxylate
CAS 2385239-07-4C13H22INO3
![2-{2-[(tert-Butoxy)carbonyl]-6-oxa-2-azaspiro[3.5]nonan-7-yl}acetic acid chemical structure, C14H23NO5, CAS 2418643-27-1](/s/MARLLIMKWYSPIB-UHFFFAOYSA-N.svg)
2-{2-[(tert-Butoxy)carbonyl]-6-oxa-2-azaspiro[3.5]nonan-7-yl}acetic acid
CAS 2418643-27-1C14H23NO5
![7-Methyl-6-oxa-2-azaspiro[3.5]nonane hydrochloride chemical structure, C8H16ClNO, CAS 2418695-87-9](/s/MFXNXCHEWDQCNX-UHFFFAOYSA-N.svg)
7-Methyl-6-oxa-2-azaspiro[3.5]nonane hydrochloride
CAS 2418695-87-9C8H16ClNO
![2-{6-Oxa-2-azaspiro[3.5]nonan-7-yl}acetic acid, trifluoroacetic acid chemical structure, C11H16F3NO5, CAS 2445790-70-3](/s/AAFSFBSRGUMLQH-UHFFFAOYSA-N.svg)
2-{6-Oxa-2-azaspiro[3.5]nonan-7-yl}acetic acid, trifluoroacetic acid
CAS 2445790-70-3C11H16F3NO5
![2-{6-Oxa-2-azaspiro[3.5]nonan-7-yl}acetic acid chemical structure, C9H15NO3, CAS 2445790-69-0](/s/DEHJIVWWXGNSHW-UHFFFAOYSA-N.svg)
2-{6-Oxa-2-azaspiro[3.5]nonan-7-yl}acetic acid
CAS 2445790-69-0C9H15NO3
![Methyl 2-{6-oxa-2-azaspiro[3.5]nonan-7-yl}acetate, trifluoroacetic acid chemical structure, C12H18F3NO5, CAS 2445791-53-5](/s/KSEMFLJFUNIIRR-UHFFFAOYSA-N.svg)
Methyl 2-{6-oxa-2-azaspiro[3.5]nonan-7-yl}acetate, trifluoroacetic acid
CAS 2445791-53-5C12H18F3NO5
![Methyl 2-{6-oxa-2-azaspiro[3.5]nonan-7-yl}acetate chemical structure, C10H17NO3, CAS 2445790-87-2](/s/YDCFOQQSUWCNQB-UHFFFAOYSA-N.svg)
Methyl 2-{6-oxa-2-azaspiro[3.5]nonan-7-yl}acetate
CAS 2445790-87-2C10H17NO3
![2-[(tert-Butoxy)carbonyl]-6-oxa-2-azaspiro[3.5]nonane-7-carboxylic acid chemical structure, C13H21NO5, CAS 1251022-87-3](/s/SRYYLHVDTOXDGH-UHFFFAOYSA-N.svg)
2-[(tert-Butoxy)carbonyl]-6-oxa-2-azaspiro[3.5]nonane-7-carboxylic acid
CAS 1251022-87-3C13H21NO5
![2,2,2-Trifluoro-1-{6-oxa-2-azaspiro[3.5]nonan-2-yl}ethan-1-one chemical structure, C9H12F3NO2, CAS 2613382-39-9](/s/LDFYJYTVJADQHO-UHFFFAOYSA-N.svg)
2,2,2-Trifluoro-1-{6-oxa-2-azaspiro[3.5]nonan-2-yl}ethan-1-one
CAS 2613382-39-9C9H12F3NO2
Methyl 6-oxa-2-azaspiro(3.5)nonane-7-carboxylate hydrochloride
CAS 2639413-95-7C9H16ClNO3
![Methyl 6-oxa-2-azaspiro[3.5]nonane-7-carboxylate chemical structure, C9H15NO3, CAS 2580237-63-2](/s/JSLJFRIETSPKLH-UHFFFAOYSA-N.svg)
Methyl 6-oxa-2-azaspiro[3.5]nonane-7-carboxylate
CAS 2580237-63-2C9H15NO3
![6-Oxa-2-azaspiro[3.5]nonane-7-carboxylic acid, trifluoroacetic acid chemical structure, C10H14F3NO5, CAS 2624137-65-9](/s/UYITYAIBYSDIGV-UHFFFAOYSA-N.svg)
6-Oxa-2-azaspiro[3.5]nonane-7-carboxylic acid, trifluoroacetic acid
CAS 2624137-65-9C10H14F3NO5
![6-Oxa-2-azaspiro[3.5]nonane-7-carboxylic acid chemical structure, C8H13NO3, CAS 2580184-84-3](/s/FGUOFKVAYNSWKY-UHFFFAOYSA-N.svg)
6-Oxa-2-azaspiro[3.5]nonane-7-carboxylic acid
CAS 2580184-84-3C8H13NO3
![7,7-Dimethyl-6-oxa-2-azaspiro[3.5]nonane hydrochloride chemical structure, C9H18ClNO, CAS 2742660-62-2](/s/UPRJXUXQSGFFPT-UHFFFAOYSA-N.svg)
7,7-Dimethyl-6-oxa-2-azaspiro[3.5]nonane hydrochloride
CAS 2742660-62-2C9H18ClNO
![7,7-Dimethyl-6-oxa-2-azaspiro[3.5]nonane chemical structure, C9H17NO, CAS 2167516-27-8](/s/IDDUTCGHFPOGBR-UHFFFAOYSA-N.svg)
7,7-Dimethyl-6-oxa-2-azaspiro[3.5]nonane
CAS 2167516-27-8C9H17NO
![Ethyl 2-{6-oxa-2-azaspiro[3.5]nonan-7-yl}acetate chemical structure, C11H19NO3, CAS 2580198-71-4](/s/XHLOZGSUVZIRBA-UHFFFAOYSA-N.svg)
Ethyl 2-{6-oxa-2-azaspiro[3.5]nonan-7-yl}acetate
CAS 2580198-71-4C11H19NO3
![tert-Butyl 6-oxa-2-azaspiro[3.5]nonane-7-carboxylate chemical structure, C12H21NO3, CAS 2580215-30-9](/s/WPGQCLVAGRMQEB-UHFFFAOYSA-N.svg)
tert-Butyl 6-oxa-2-azaspiro[3.5]nonane-7-carboxylate
CAS 2580215-30-9C12H21NO3
- Ethyl 6-oxa-2-azaspiro[3.5]nonane-7-carboxylate2580253-60-5C10H17NO3
- tert-Butyl 2-{6-oxa-2-azaspiro[3.5]nonan-7-yl}acetate2639410-16-3C13H23NO3
- 2-Acetyl-6-oxa-2-azaspiro[3.5]nonane-7-carboxylic acid2680850-59-1C10H15NO4
- 7-(Iodomethyl)-6-oxa-2-azaspiro[3.5]nonane2680849-21-0C8H14INO
- 2-(2,2,2-Trifluoroacetyl)-6-oxa-2-azaspiro[3.5]nonane-7-carboxylic acid2680794-09-4C10H12F3NO4
- 2-[(Prop-2-en-1-yloxy)carbonyl]-6-oxa-2-azaspiro[3.5]nonane-7-carboxylic acid2680801-07-2C12H17NO5
- 2-{2-[(Prop-2-en-1-yloxy)carbonyl]-6-oxa-2-azaspiro[3.5]nonan-7-yl}acetic acid2680845-94-5C13H19NO5
- 2-{2-Acetyl-6-oxa-2-azaspiro[3.5]nonan-7-yl}acetic acid2680855-17-6C11H17NO4
- 2-[2-(2,2,2-Trifluoroacetyl)-6-oxa-2-azaspiro[3.5]nonan-7-yl]acetic acid2680690-90-6C11H14F3NO4
- 1-{6-Oxa-2-azaspiro[3.5]nonan-7-yl}methanamine2680660-98-2C8H16N2O
- 8-Fluoro-6-oxa-2-azaspiro[3.5]nonane2925089-71-8C7H12FNO
- 9-Fluoro-6-oxa-2-azaspiro[3.5]nonane2925081-70-3C7H12FNO
- 9,9-Difluoro-6-oxa-2-azaspiro[3.5]nonane2925068-81-9C7H11F2NO
- 8,8-Difluoro-6-oxa-2-azaspiro[3.5]nonane2925075-80-3C7H11F2NO
- tert-Butyl 9-amino-6-oxa-2-azaspiro[3.5]nonane-2-carboxylate2955543-09-4C12H22N2O3
- tert-Butyl 8-amino-6-oxa-2-azaspiro[3.5]nonane-2-carboxylate2955543-39-0C12H22N2O3
- tert-Butyl 8-hydroxy-6-oxa-2-azaspiro[3.5]nonane-2-carboxylate2955551-93-4C12H21NO4
- 2-[(tert-Butoxy)carbonyl]-6-oxa-2-azaspiro[3.5]nonane-9-carboxylic acid2955561-59-6C13H21NO5
- 2-[(tert-Butoxy)carbonyl]-6-oxa-2-azaspiro[3.5]nonane-8-carboxylic acid2955544-06-4C13H21NO5
- 2-[(tert-Butoxy)carbonyl]-6-oxa-2-azaspiro[3.5]nonane-5-carboxylic acid2955543-61-8C13H21NO5
- tert-Butyl 7-(aminomethyl)-7-methyl-6-oxa-2-azaspiro[3.5]nonane-2-carboxylate hydrochloride3026713-25-4C14H27ClN2O3
Related scaffolds
Same ring framework with different atoms or bond orders
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C1CCC2(CCC2)OC126 chemicals
C1CC2(C1)CNCCO219 chemicals
C1CC2(CCN1)CNC215 chemicals
C1CCC2(CC1)CNC214 chemicals
C1CCC2(CCC2)NC114 chemicals
C1CCC2(CC1)CCN212 chemicals
C1COCC2(C1)CCC210 chemicals
C1CC2(C1)COCCN210 chemicals