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Murcko scaffold

Ring system with 3 rings and 20 atoms

62 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
62
With full pages
7
Scaffold SMILES

O=C(Nc1ccccc1)c1cnc2ccccn2c1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1cnc2ccccn2c1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 62 chemicals

4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(4-methylphenyl)-4-oxo- chemical structure, C16H13N3O2, CAS 172753-13-8
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(4-methylphenyl)-4-oxo-
CAS 172753-13-8C16H13N3O2
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(2-methylphenyl)-4-oxo- chemical structure, C16H13N3O2, CAS 172753-14-9
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(2-methylphenyl)-4-oxo-
CAS 172753-14-9C16H13N3O2
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(4-methoxyphenyl)-4-oxo- chemical structure, C16H13N3O3, CAS 172753-15-0
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(4-methoxyphenyl)-4-oxo-
CAS 172753-15-0C16H13N3O3
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(2-methoxyphenyl)-4-oxo- chemical structure, C16H13N3O3, CAS 172753-16-1
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(2-methoxyphenyl)-4-oxo-
CAS 172753-16-1C16H13N3O3
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, 6-methyl-4-oxo-N-phenyl- chemical structure, C16H13N3O2, CAS 125055-65-4
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, 6-methyl-4-oxo-N-phenyl-
CAS 125055-65-4C16H13N3O2
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(4-fluorophenyl)-6-methyl-4-oxo- chemical structure, C16H12FN3O2, CAS 125055-66-5
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(4-fluorophenyl)-6-methyl-4-oxo-
CAS 125055-66-5C16H12FN3O2
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(4-chlorophenyl)-6-methyl-4-oxo- chemical structure, C16H12ClN3O2, CAS 125055-67-6
4H-Pyrido(1,2-a)pyrimidine-3-carboxamide, N-(4-chlorophenyl)-6-methyl-4-oxo-
CAS 125055-67-6C16H12ClN3O2
N-(2,5-Dimethoxyphenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C17H15N3O4, CAS 847411-31-8
N-(2,5-Dimethoxyphenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 847411-31-8C17H15N3O4
N-(4-Acetylphenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C17H13N3O3, CAS 847411-12-5
N-(4-Acetylphenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 847411-12-5C17H13N3O3
N-(2-Ethylphenyl)-8-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C18H17N3O2, CAS 847411-60-3
N-(2-Ethylphenyl)-8-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 847411-60-3C18H17N3O2
8-Methyl-4-oxo-N-[2-(trifluoromethyl)phenyl]pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C17H12F3N3O2, CAS 847411-61-4
8-Methyl-4-oxo-N-[2-(trifluoromethyl)phenyl]pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 847411-61-4C17H12F3N3O2
8-Methyl-4-oxo-N-(4-(trifluoromethyl)phenyl)-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C17H12F3N3O2, CAS 847411-63-6
8-Methyl-4-oxo-N-(4-(trifluoromethyl)phenyl)-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 847411-63-6C17H12F3N3O2
4-Oxo-N-(4-sulfamoylphenyl)-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C15H12N4O4S, CAS 847411-17-0
4-Oxo-N-(4-sulfamoylphenyl)-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 847411-17-0C15H12N4O4S
N-(2,4-Difluorophenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C15H9F2N3O2, CAS 847411-20-5
N-(2,4-Difluorophenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 847411-20-5C15H9F2N3O2
N-(2,5-Difluorophenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C15H9F2N3O2, CAS 847411-22-7
N-(2,5-Difluorophenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 847411-22-7C15H9F2N3O2
N-(2,4-Dimethoxyphenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C17H15N3O4, CAS 847411-30-7
N-(2,4-Dimethoxyphenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 847411-30-7C17H15N3O4
Methyl 2-[(8-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbonyl)amino]benzoate chemical structure, C18H15N3O4, CAS 896678-89-0
Methyl 2-[(8-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbonyl)amino]benzoate
CAS 896678-89-0C18H15N3O4
N-(2,4-Difluorophenyl)-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C16H11F2N3O2, CAS 877650-45-8
N-(2,4-Difluorophenyl)-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 877650-45-8C16H11F2N3O2
N-(4-Bromo-2,6-dimethylphenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C17H14BrN3O2, CAS 863005-62-3
N-(4-Bromo-2,6-dimethylphenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 863005-62-3C17H14BrN3O2
7-Methyl-4-oxo-N-[3-(trifluoromethyl)phenyl]-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C17H12F3N3O2, CAS 877649-71-3
7-Methyl-4-oxo-N-[3-(trifluoromethyl)phenyl]-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 877649-71-3C17H12F3N3O2
7-Methyl-4-oxo-N-[4-(trifluoromethoxy)phenyl]-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C17H12F3N3O3, CAS 877649-82-6
7-Methyl-4-oxo-N-[4-(trifluoromethoxy)phenyl]-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 877649-82-6C17H12F3N3O3
Butyl 4-(7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamido)benzoate chemical structure, C21H21N3O4, CAS 877649-92-8
Butyl 4-(7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamido)benzoate
CAS 877649-92-8C21H21N3O4
N-(2-Methoxy-5-methylphenyl)-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C18H17N3O3, CAS 896013-82-4
N-(2-Methoxy-5-methylphenyl)-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 896013-82-4C18H17N3O3
N-(4-Butylphenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide chemical structure, C19H19N3O2, CAS 847410-97-3
N-(4-Butylphenyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxamide
CAS 847410-97-3C19H19N3O2