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Murcko scaffold

Acetamide, N-(1-naphthyl)-2-phenyl- scaffold

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
18
With full pages
3
Scaffold SMILES

O=C(Cc1ccccc1)Nc1cccc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Acetamide, N-(1-naphthyl)-2-phenyl- page
Murcko scaffold O=C(Cc1ccccc1)Nc1cccc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

Acetamide, N-(1-naphthyl)-2-phenyl- chemical structure, C18H15NO, CAS 73548-14-8
Acetamide, N-(1-naphthyl)-2-phenyl-
CAS 73548-14-8C18H15NO
2-(2,4-Difluorophenyl)-N-naphthalen-1-ylacetamide chemical structure, C18H13F2NO, CAS 5364-72-7
2-(2,4-Difluorophenyl)-N-naphthalen-1-ylacetamide
CAS 5364-72-7C18H13F2NO
2-(2-Methoxyphenyl)-N-naphthalen-1-ylacetamide chemical structure, C19H17NO2, CAS 690668-52-1
2-(2-Methoxyphenyl)-N-naphthalen-1-ylacetamide
CAS 690668-52-1C19H17NO2
2-(2-Fluorophenyl)-N-naphthalen-1-ylacetamide chemical structure, C18H14FNO, CAS 562797-10-8
2-(2-Fluorophenyl)-N-naphthalen-1-ylacetamide
CAS 562797-10-8C18H14FNO
2-(4-Methylphenyl)-N-naphthalen-1-ylacetamide chemical structure, C19H17NO, CAS 694445-69-7
2-(4-Methylphenyl)-N-naphthalen-1-ylacetamide
CAS 694445-69-7C19H17NO
N-[4-(Dimethylamino)naphthalen-1-yl]-2-phenylacetamide chemical structure, C20H20N2O, CAS 428482-25-1
N-[4-(Dimethylamino)naphthalen-1-yl]-2-phenylacetamide
CAS 428482-25-1C20H20N2O
2-(2-Chlorophenyl)-N-naphthalen-1-ylacetamide chemical structure, C18H14ClNO, CAS 930688-95-2
2-(2-Chlorophenyl)-N-naphthalen-1-ylacetamide
CAS 930688-95-2C18H14ClNO
2-(3,4-Dimethoxyphenyl)-N-naphthalen-1-ylacetamide chemical structure, C20H19NO3, CAS 551926-02-4
2-(3,4-Dimethoxyphenyl)-N-naphthalen-1-ylacetamide
CAS 551926-02-4C20H19NO3
N-Naphthalen-1-yl-2-phenylbutanamide chemical structure, C20H19NO, CAS 157182-82-6
N-Naphthalen-1-yl-2-phenylbutanamide
CAS 157182-82-6C20H19NO
2-(3-Fluorophenyl)-N-naphthalen-1-ylacetamide chemical structure, C18H14FNO, CAS 881594-69-0
2-(3-Fluorophenyl)-N-naphthalen-1-ylacetamide
CAS 881594-69-0C18H14FNO
2-[4-(2-Methylpropyl)phenyl]-N-naphthalen-1-ylpropanamide chemical structure, C23H25NO, CAS 110501-25-2
2-[4-(2-Methylpropyl)phenyl]-N-naphthalen-1-ylpropanamide
CAS 110501-25-2C23H25NO
2-(2,4-Dimethylphenyl)-N-(4-methoxynaphthalen-1-yl)acetamide chemical structure, C21H21NO2, CAS 899958-31-7
2-(2,4-Dimethylphenyl)-N-(4-methoxynaphthalen-1-yl)acetamide
CAS 899958-31-7C21H21NO2
2-(4-Fluorophenyl)-N-(4-methoxynaphthalen-1-yl)acetamide chemical structure, C19H16FNO2, CAS 899731-84-1
2-(4-Fluorophenyl)-N-(4-methoxynaphthalen-1-yl)acetamide
CAS 899731-84-1C19H16FNO2
N-(4-Methoxynaphthalen-1-yl)-2-(4-(methylthio)phenyl)acetamide chemical structure, C20H19NO2S, CAS 941883-13-2
N-(4-Methoxynaphthalen-1-yl)-2-(4-(methylthio)phenyl)acetamide
CAS 941883-13-2C20H19NO2S
2-(4-(Methylsulfonyl)phenyl)-N-(naphthalen-1-yl)acetamide chemical structure, C19H17NO3S, CAS 942008-60-8
2-(4-(Methylsulfonyl)phenyl)-N-(naphthalen-1-yl)acetamide
CAS 942008-60-8C19H17NO3S
N-(4-Methoxynaphthalen-1-yl)-2-(4-(methylsulfonyl)phenyl)acetamide chemical structure, C20H19NO4S, CAS 941883-73-4
N-(4-Methoxynaphthalen-1-yl)-2-(4-(methylsulfonyl)phenyl)acetamide
CAS 941883-73-4C20H19NO4S
2-(4-(Ethylsulfonyl)phenyl)-N-(naphthalen-1-yl)acetamide chemical structure, C20H19NO3S, CAS 941972-34-5
2-(4-(Ethylsulfonyl)phenyl)-N-(naphthalen-1-yl)acetamide
CAS 941972-34-5C20H19NO3S
2-(4-(Ethylsulfonyl)phenyl)-N-(4-methoxynaphthalen-1-yl)acetamide chemical structure, C21H21NO4S, CAS 941884-55-5
2-(4-(Ethylsulfonyl)phenyl)-N-(4-methoxynaphthalen-1-yl)acetamide
CAS 941884-55-5C21H21NO4S