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Murcko scaffold

2-Azetidinone scaffold

485 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
485
With full pages
48
Scaffold SMILES

O=C1CCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2-Azetidinone page
Murcko scaffold O=C1CCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 485 chemicals

2-((4-Oxoazetidin-2-yl)thio)acetic acid chemical structure, C5H7NO3S, CAS 31898-75-6
2-((4-Oxoazetidin-2-yl)thio)acetic acid
CAS 31898-75-6C5H7NO3S
(3S,4R)-3-Chloro-4-[(R)-methanesulfinyl]azetidin-2-one chemical structure, C4H6ClNO2S, CAS 80241-75-4
(3S,4R)-3-Chloro-4-[(R)-methanesulfinyl]azetidin-2-one
CAS 80241-75-4C4H6ClNO2S
(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic acid chemical structure, C4H8N2O4S, CAS 112026-42-3
(2R,3R)-3-Amino-2-methyl-4-oxoazetidine-1-sulfonic acid
CAS 112026-42-3C4H8N2O4S
(2S,3S)-3-{[(tert-Butoxy)carbonyl]amino}-2-methyl-4-oxoazetidine-1-sulfonic acid chemical structure, C9H16N2O6S, CAS 1128192-66-4
(2S,3S)-3-{[(tert-Butoxy)carbonyl]amino}-2-methyl-4-oxoazetidine-1-sulfonic acid
CAS 1128192-66-4C9H16N2O6S
tert-Butyl ((2S,3S)-2-methyl-4-oxoazetidin-3-yl)carbamate chemical structure, C9H16N2O3, CAS 80582-03-2
tert-Butyl ((2S,3S)-2-methyl-4-oxoazetidin-3-yl)carbamate
CAS 80582-03-2C9H16N2O3
(3S,4S)-3-Amino-4-methylazetidin-2-one chemical structure, C4H8N2O, CAS 87791-62-6
(3S,4S)-3-Amino-4-methylazetidin-2-one
CAS 87791-62-6C4H8N2O
4-Ethynyl-3-(1-hydroxyethyl)azetidin-2-one chemical structure, C7H9NO2, CAS 103365-28-2
4-Ethynyl-3-(1-hydroxyethyl)azetidin-2-one
CAS 103365-28-2C7H9NO2
tert-Butyl (3-methyl-2-oxoazetidin-3-yl)carbamate chemical structure, C9H16N2O3, CAS 89500-43-6
tert-Butyl (3-methyl-2-oxoazetidin-3-yl)carbamate
CAS 89500-43-6C9H16N2O3
3-(Prop-1-en-2-yl)azetidin-2-one chemical structure, C6H9NO, CAS 89368-03-6
3-(Prop-1-en-2-yl)azetidin-2-one
CAS 89368-03-6C6H9NO
2-Azetidinone, 3-amino-1-hydroxy- chemical structure, C3H6N2O2, CAS 95545-33-8
2-Azetidinone, 3-amino-1-hydroxy-
CAS 95545-33-8C3H6N2O2
(3S)-3-Amino-1-hydroxyazetidin-2-one chemical structure, C3H6N2O2, CAS 82933-36-6
(3S)-3-Amino-1-hydroxyazetidin-2-one
CAS 82933-36-6C3H6N2O2
(3S,4S)-3-Amino-4-(fluoromethyl)azetidin-2-one chemical structure, C4H7FN2O, CAS 90121-66-7
(3S,4S)-3-Amino-4-(fluoromethyl)azetidin-2-one
CAS 90121-66-7C4H7FN2O
1,3,3-Trimethyl-azetidin-2-one chemical structure, C6H11NO, CAS 27983-92-2
1,3,3-Trimethyl-azetidin-2-one
CAS 27983-92-2C6H11NO
3,3,4-Trimethylazetidin-2-one chemical structure, C6H11NO, CAS 13423-21-7
3,3,4-Trimethylazetidin-2-one
CAS 13423-21-7C6H11NO
3,3-Dimethyl-1-(2-methylpropyl)-4-(propan-2-yl)azetidin-2-one chemical structure, C12H23NO, CAS 88413-86-9
3,3-Dimethyl-1-(2-methylpropyl)-4-(propan-2-yl)azetidin-2-one
CAS 88413-86-9C12H23NO
1,3,3,4-Tetramethylazetidin-2-one chemical structure, C7H13NO, CAS 88413-83-6
1,3,3,4-Tetramethylazetidin-2-one
CAS 88413-83-6C7H13NO
1-[tert-Butyl(dimethyl)silyl]-4-(ethylsulfanyl)azetidin-2-one chemical structure, C11H23NOSSi, CAS 76431-26-0
1-[tert-Butyl(dimethyl)silyl]-4-(ethylsulfanyl)azetidin-2-one
CAS 76431-26-0C11H23NOSSi
3-Methylazetidin-2-one chemical structure, C4H7NO, CAS 58521-61-2
3-Methylazetidin-2-one
CAS 58521-61-2C4H7NO
2-(4-Oxoazetidin-2-yl)ethyl methanesulfonate chemical structure, C6H11NO4S, CAS 89229-89-0
2-(4-Oxoazetidin-2-yl)ethyl methanesulfonate
CAS 89229-89-0C6H11NO4S
1-[tert-Butyl(dimethyl)silyl]-4-(prop-2-yn-1-yl)azetidin-2-one chemical structure, C12H21NOSi, CAS 81355-48-8
1-[tert-Butyl(dimethyl)silyl]-4-(prop-2-yn-1-yl)azetidin-2-one
CAS 81355-48-8C12H21NOSi
4-Butyl-1-methylazetidin-2-one chemical structure, C8H15NO, CAS 85091-12-9
4-Butyl-1-methylazetidin-2-one
CAS 85091-12-9C8H15NO
Carbamic acid, [2-(acetyloxy)-4-oxo-3-azetidinyl]-, 1,1-dimethylethyl ester, (2S-trans)- chemical structure, C10H16N2O5, CAS 96901-17-6
Carbamic acid, [2-(acetyloxy)-4-oxo-3-azetidinyl]-, 1,1-dimethylethyl ester, (2S-trans)-
CAS 96901-17-6C10H16N2O5
4-(sec-Butyl)azetidin-2-one chemical structure, C7H13NO, CAS 97033-10-8
4-(sec-Butyl)azetidin-2-one
CAS 97033-10-8C7H13NO
4-tert-Butylazetidin-2-one chemical structure, C7H13NO, CAS 97033-11-9
4-tert-Butylazetidin-2-one
CAS 97033-11-9C7H13NO