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Murcko scaffold

2-Azetidinone scaffold

485 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
485
With full pages
48
Scaffold SMILES

O=C1CCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2-Azetidinone page
Murcko scaffold O=C1CCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 485 chemicals

(S)-tert-Butyl (1-hydroxy-2,2-dimethyl-4-oxoazetidin-3-yl)carbamate chemical structure, C10H18N2O4, CAS 102507-31-3
(S)-tert-Butyl (1-hydroxy-2,2-dimethyl-4-oxoazetidin-3-yl)carbamate
CAS 102507-31-3C10H18N2O4
(S)-3-((tert-Butoxycarbonyl)amino)-2,2-dimethyl-4-oxoazetidin-1-yl hydrogen sulfate chemical structure, C10H18N2O7S, CAS 102507-37-9
(S)-3-((tert-Butoxycarbonyl)amino)-2,2-dimethyl-4-oxoazetidin-1-yl hydrogen sulfate
CAS 102507-37-9C10H18N2O7S
(S)-3-Amino-2,2-dimethyl-4-oxoazetidin-1-yl hydrogen sulfate chemical structure, C5H10N2O5S, CAS 102507-49-3
(S)-3-Amino-2,2-dimethyl-4-oxoazetidin-1-yl hydrogen sulfate
CAS 102507-49-3C5H10N2O5S
tert-Butyl 2-(4-oxoazetidin-2-yl)acetate chemical structure, C9H15NO3, CAS 88598-15-6
tert-Butyl 2-(4-oxoazetidin-2-yl)acetate
CAS 88598-15-6C9H15NO3
1-(tert-Butyldimethylsilyl)azetidin-2-one chemical structure, C9H19NOSi, CAS 117505-49-4
1-(tert-Butyldimethylsilyl)azetidin-2-one
CAS 117505-49-4C9H19NOSi
1-(t-Butyldimethylsilyl)-4-vinyl-2-azetidinone chemical structure, C11H21NOSi, CAS 71634-52-1
1-(t-Butyldimethylsilyl)-4-vinyl-2-azetidinone
CAS 71634-52-1C11H21NOSi
Methyl (2R,3R)-3-ethyl-4-oxoazetidine-2-carboxylate chemical structure, C7H11NO3, CAS 125639-92-1
Methyl (2R,3R)-3-ethyl-4-oxoazetidine-2-carboxylate
CAS 125639-92-1C7H11NO3
(2S)-1-[(1,1-Dimethylethyl)dimethylsilyl]-4-oxo-2-azetidineacetic acid chemical structure, C11H21NO3Si, CAS 77856-54-3
(2S)-1-[(1,1-Dimethylethyl)dimethylsilyl]-4-oxo-2-azetidineacetic acid
CAS 77856-54-3C11H21NO3Si
(3-Amino-4-oxoazetidin-2-yl)methyl carbamate chemical structure, C5H9N3O3, CAS 405061-16-7
(3-Amino-4-oxoazetidin-2-yl)methyl carbamate
CAS 405061-16-7C5H9N3O3
(3R,4S)-4-Acetyl-3-ethylazetidin-2-one chemical structure, C7H11NO2, CAS 116179-68-1
(3R,4S)-4-Acetyl-3-ethylazetidin-2-one
CAS 116179-68-1C7H11NO2
Methyl (2R,3R)-3-amino-4-oxoazetidine-2-carboxylate chemical structure, C5H8N2O3, CAS 72079-37-9
Methyl (2R,3R)-3-amino-4-oxoazetidine-2-carboxylate
CAS 72079-37-9C5H8N2O3
[(2S,3R)-4-Oxo-3-propan-2-ylazetidin-2-yl] acetate chemical structure, C8H13NO3, CAS 127127-64-4
[(2S,3R)-4-Oxo-3-propan-2-ylazetidin-2-yl] acetate
CAS 127127-64-4C8H13NO3
[(2R,3R)-4-Oxo-3-propan-2-ylazetidin-2-yl] acetate chemical structure, C8H13NO3, CAS 127127-62-2
[(2R,3R)-4-Oxo-3-propan-2-ylazetidin-2-yl] acetate
CAS 127127-62-2C8H13NO3
3,4-Bis(propan-2-yl)azetidin-2-one chemical structure, C9H17NO, CAS 1856133-57-7
3,4-Bis(propan-2-yl)azetidin-2-one
CAS 1856133-57-7C9H17NO
tert-Butyl ((2S,3S)-2-(hydroxymethyl)-4-oxoazetidin-3-yl)carbamate chemical structure, C9H16N2O4, CAS 110312-83-9
tert-Butyl ((2S,3S)-2-(hydroxymethyl)-4-oxoazetidin-3-yl)carbamate
CAS 110312-83-9C9H16N2O4
tert-Butyl [(2S,3S)-2-(hydroxymethyl)-4-oxoazetidin-3-yl]carbamate chemical structure, C9H16N2O4
tert-Butyl [(2S,3S)-2-(hydroxymethyl)-4-oxoazetidin-3-yl]carbamate
C9H16N2O4
2-Azetidinone, 3-ethyl-4-ethynyl-, (3R-trans)- chemical structure, C7H9NO, CAS 134250-80-9
2-Azetidinone, 3-ethyl-4-ethynyl-, (3R-trans)-
CAS 134250-80-9C7H9NO
(3S)-3-Amino-1-[tert-butyl(dimethyl)silyl]azetidin-2-one chemical structure, C9H20N2OSi, CAS 88164-21-0
(3S)-3-Amino-1-[tert-butyl(dimethyl)silyl]azetidin-2-one
CAS 88164-21-0C9H20N2OSi
1-Butyl-3-methylazetidin-2-one chemical structure, C8H15NO, CAS 883899-12-5
1-Butyl-3-methylazetidin-2-one
CAS 883899-12-5C8H15NO
tert-Butyl (1-amino-2-oxoazetidin-3-yl)carbamate chemical structure, C8H15N3O3, CAS 1822581-31-6
tert-Butyl (1-amino-2-oxoazetidin-3-yl)carbamate
CAS 1822581-31-6C8H15N3O3
3-Ethyl-3-methylazetidin-2-one chemical structure, C6H11NO, CAS 59186-07-1
3-Ethyl-3-methylazetidin-2-one
CAS 59186-07-1C6H11NO
Methyl 2-oxoazetidine-1-carboxylate chemical structure, C5H7NO3, CAS 400713-76-0
Methyl 2-oxoazetidine-1-carboxylate
CAS 400713-76-0C5H7NO3
4-(tert-Butylsulfanyl)azetidin-2-one chemical structure, C7H13NOS, CAS 79669-40-2
4-(tert-Butylsulfanyl)azetidin-2-one
CAS 79669-40-2C7H13NOS
N-(2-Propynyl)-4-methyl-2-azetidinone chemical structure, C7H9NO, CAS 124443-42-1
N-(2-Propynyl)-4-methyl-2-azetidinone
CAS 124443-42-1C7H9NO