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Murcko scaffold

[1,1'-Biphenyl]-4-sulfonamide, N-phenyl- scaffold

29 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
29
With full pages
3
Scaffold SMILES

O=S(=O)(Nc1ccccc1)c1ccc(-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the [1,1'-Biphenyl]-4-sulfonamide, N-phenyl- page
Murcko scaffold O=S(=O)(Nc1ccccc1)c1ccc(-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

N-(3-Fluorophenyl)-4-phenylbenzenesulfonamide chemical structure, C18H14FNO2S, CAS 313550-61-7
N-(3-Fluorophenyl)-4-phenylbenzenesulfonamide
CAS 313550-61-7C18H14FNO2S
[1,1'-Biphenyl]-4-sulfonamide, N-(3-methylphenyl)- chemical structure, C19H17NO2S, CAS 291536-80-6
[1,1'-Biphenyl]-4-sulfonamide, N-(3-methylphenyl)-
CAS 291536-80-6C19H17NO2S
N-(4-Fluorophenyl)-4'-methyl-[1,1'-biphenyl]-4-sulfonamide chemical structure, C19H16FNO2S, CAS 670271-68-8
N-(4-Fluorophenyl)-4'-methyl-[1,1'-biphenyl]-4-sulfonamide
CAS 670271-68-8C19H16FNO2S
4'-Chloro-N-(4-fluorophenyl)[1,1'-biphenyl]-4-sulfonamide chemical structure, C18H13ClFNO2S, CAS 667912-53-0
4'-Chloro-N-(4-fluorophenyl)[1,1'-biphenyl]-4-sulfonamide
CAS 667912-53-0C18H13ClFNO2S
N-(4-Ethoxyphenyl)-4'-methyl-[1,1'-biphenyl]-4-sulfonamide chemical structure, C21H21NO3S, CAS 667912-63-2
N-(4-Ethoxyphenyl)-4'-methyl-[1,1'-biphenyl]-4-sulfonamide
CAS 667912-63-2C21H21NO3S
4-[(Biphenyl-4-ylsulfonyl)amino]benzoic acid chemical structure, C19H15NO4S, CAS 331653-75-9
4-[(Biphenyl-4-ylsulfonyl)amino]benzoic acid
CAS 331653-75-9C19H15NO4S
4'-Chloro-N-(4-methoxyphenyl)-[1,1'-biphenyl]-4-sulfonamide chemical structure, C19H16ClNO3S, CAS 670271-49-5
4'-Chloro-N-(4-methoxyphenyl)-[1,1'-biphenyl]-4-sulfonamide
CAS 670271-49-5C19H16ClNO3S
4'-Methoxy-N-(4-methoxyphenyl)-[1,1'-biphenyl]-4-sulfonamide chemical structure, C20H19NO4S, CAS 670271-50-8
4'-Methoxy-N-(4-methoxyphenyl)-[1,1'-biphenyl]-4-sulfonamide
CAS 670271-50-8C20H19NO4S
4'-Methoxy-N-(3-methoxyphenyl)-[1,1'-biphenyl]-4-sulfonamide chemical structure, C20H19NO4S, CAS 670271-54-2
4'-Methoxy-N-(3-methoxyphenyl)-[1,1'-biphenyl]-4-sulfonamide
CAS 670271-54-2C20H19NO4S
N-(4-Acetylphenyl)-4'-methyl-[1,1'-biphenyl]-4-sulfonamide chemical structure, C21H19NO3S, CAS 670272-71-6
N-(4-Acetylphenyl)-4'-methyl-[1,1'-biphenyl]-4-sulfonamide
CAS 670272-71-6C21H19NO3S
N-(3-Acetylphenyl)-4'-methyl-[1,1'-biphenyl]-4-sulfonamide chemical structure, C21H19NO3S, CAS 670272-70-5
N-(3-Acetylphenyl)-4'-methyl-[1,1'-biphenyl]-4-sulfonamide
CAS 670272-70-5C21H19NO3S
4'-Methoxy-N-(2-methoxyphenyl)-[1,1'-biphenyl]-4-sulfonamide chemical structure, C20H19NO4S, CAS 670271-59-7
4'-Methoxy-N-(2-methoxyphenyl)-[1,1'-biphenyl]-4-sulfonamide
CAS 670271-59-7C20H19NO4S
N-(3-Methoxyphenyl)-4'-methyl-[1,1'-biphenyl]-4-sulfonamide chemical structure, C20H19NO3S, CAS 670271-53-1
N-(3-Methoxyphenyl)-4'-methyl-[1,1'-biphenyl]-4-sulfonamide
CAS 670271-53-1C20H19NO3S
4'-Chloro-N-(2-fluorophenyl)-[1,1'-biphenyl]-4-sulfonamide chemical structure, C18H13ClFNO2S, CAS 670271-89-3
4'-Chloro-N-(2-fluorophenyl)-[1,1'-biphenyl]-4-sulfonamide
CAS 670271-89-3C18H13ClFNO2S
4'-Methyl-N-phenyl-N-(2,2,2-trifluoroethyl)-[1,1'-biphenyl]-4-sulfonamide chemical structure, C21H18F3NO2S, CAS 690644-37-2
4'-Methyl-N-phenyl-N-(2,2,2-trifluoroethyl)-[1,1'-biphenyl]-4-sulfonamide
CAS 690644-37-2C21H18F3NO2S
[1,1'-Biphenyl]-4-sulfonamide, N-phenyl- chemical structure, C18H15NO2S, CAS 109135-65-1
[1,1'-Biphenyl]-4-sulfonamide, N-phenyl-
CAS 109135-65-1C18H15NO2S
Ethyl 3-(2',4'-dichlorobiphenyl-4-yl sulfonamido)benzoate chemical structure, C21H17Cl2NO4S, CAS 1062213-81-3
Ethyl 3-(2',4'-dichlorobiphenyl-4-yl sulfonamido)benzoate
CAS 1062213-81-3C21H17Cl2NO4S
4-{[(2'-Methylbiphenyl-4-yl)sulfonyl]amino}benzoic acid chemical structure, C20H17NO4S, CAS 1172292-27-1
4-{[(2'-Methylbiphenyl-4-yl)sulfonyl]amino}benzoic acid
CAS 1172292-27-1C20H17NO4S
4-{[(4'-Fluorobiphenyl-4-yl)sulfonyl]amino}benzoic acid chemical structure, C19H14FNO4S, CAS 1170846-64-6
4-{[(4'-Fluorobiphenyl-4-yl)sulfonyl]amino}benzoic acid
CAS 1170846-64-6C19H14FNO4S
4-{[(3'-Fluorobiphenyl-4-yl)sulfonyl]amino}benzoic acid chemical structure, C19H14FNO4S, CAS 1170814-13-7
4-{[(3'-Fluorobiphenyl-4-yl)sulfonyl]amino}benzoic acid
CAS 1170814-13-7C19H14FNO4S
4-(((4'-Chloro(1,1'-biphenyl)-4-yl)sulfonyl)amino)benzoic acid chemical structure, C19H14ClNO4S, CAS 885269-32-9
4-(((4'-Chloro(1,1'-biphenyl)-4-yl)sulfonyl)amino)benzoic acid
CAS 885269-32-9C19H14ClNO4S
4-((4'-Methoxy-[1,1'-biphenyl])-4-sulfonamido)benzoic acid chemical structure, C20H17NO5S, CAS 885269-42-1
4-((4'-Methoxy-[1,1'-biphenyl])-4-sulfonamido)benzoic acid
CAS 885269-42-1C20H17NO5S
3-[(4'-Methyl[1,1'-biphenyl]-4-sulfonyl)amino]benzoic acid chemical structure, C20H17NO4S, CAS 885269-85-2
3-[(4'-Methyl[1,1'-biphenyl]-4-sulfonyl)amino]benzoic acid
CAS 885269-85-2C20H17NO4S
3-((4'-Chloro-[1,1'-biphenyl])-4-sulfonamido)benzoic acid chemical structure, C19H14ClNO4S, CAS 885269-88-5
3-((4'-Chloro-[1,1'-biphenyl])-4-sulfonamido)benzoic acid
CAS 885269-88-5C19H14ClNO4S