CompoundList
Sign in
Murcko scaffold

4-Phenylazetidin-2-one scaffold

198 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
198
With full pages
13
Scaffold SMILES

O=C1CC(c2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenylazetidin-2-one page
Murcko scaffold O=C1CC(c2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 198 chemicals

1-(5-Aminopentyl)-4-phenylazetidin-2-one chemical structure, C14H20N2O, CAS 89044-88-2
1-(5-Aminopentyl)-4-phenylazetidin-2-one
CAS 89044-88-2C14H20N2O
1-[3-(Ethylamino)propyl]-4-phenylazetidin-2-one chemical structure, C14H20N2O, CAS 89044-89-3
1-[3-(Ethylamino)propyl]-4-phenylazetidin-2-one
CAS 89044-89-3C14H20N2O
4-Phenyl-1-{4-[(prop-2-en-1-yl)amino]butyl}azetidin-2-one chemical structure, C16H22N2O, CAS 89044-90-6
4-Phenyl-1-{4-[(prop-2-en-1-yl)amino]butyl}azetidin-2-one
CAS 89044-90-6C16H22N2O
4-Phenyl-1-{3-[(propan-2-yl)amino]propyl}azetidin-2-one chemical structure, C15H22N2O, CAS 89044-91-7
4-Phenyl-1-{3-[(propan-2-yl)amino]propyl}azetidin-2-one
CAS 89044-91-7C15H22N2O
(3R,4R)-3-Acetyl-4-phenyl-1-propylazetidin-2-one chemical structure, C14H17NO2, CAS 88121-68-0
(3R,4R)-3-Acetyl-4-phenyl-1-propylazetidin-2-one
CAS 88121-68-0C14H17NO2
(3R,4R)-3-Acetyl-4-phenyl-1-(propan-2-yl)azetidin-2-one chemical structure, C14H17NO2, CAS 88091-13-8
(3R,4R)-3-Acetyl-4-phenyl-1-(propan-2-yl)azetidin-2-one
CAS 88091-13-8C14H17NO2
4-Phenyl-3-(propan-2-yl)azetidin-2-one chemical structure, C12H15NO, CAS 180324-54-3
4-Phenyl-3-(propan-2-yl)azetidin-2-one
CAS 180324-54-3C12H15NO
1-tert-Butyldimethylsilyl-4-phenyl-2-azetidinone chemical structure, C15H23NOSi, CAS 96746-23-5
1-tert-Butyldimethylsilyl-4-phenyl-2-azetidinone
CAS 96746-23-5C15H23NOSi
4-(4-Bromophenyl)azetidin-2-one chemical structure, C9H8BrNO, CAS 103247-89-8
4-(4-Bromophenyl)azetidin-2-one
CAS 103247-89-8C9H8BrNO
trans-1-Methyl-3-diethylamino-4-phenyl-2-azetidinone chemical structure, C14H20N2O, CAS 113791-18-7
trans-1-Methyl-3-diethylamino-4-phenyl-2-azetidinone
CAS 113791-18-7C14H20N2O
3-Hydroxy-4-phenylazetidin-2-one chemical structure, C9H9NO2, CAS 777885-04-8
3-Hydroxy-4-phenylazetidin-2-one
CAS 777885-04-8C9H9NO2
(4S)-1-Acetyl-3,3,4-trimethyl-4-phenylazetidin-2-one chemical structure, C14H17NO2, CAS 141172-68-1
(4S)-1-Acetyl-3,3,4-trimethyl-4-phenylazetidin-2-one
CAS 141172-68-1C14H17NO2
(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate chemical structure, C20H31NO4Si, CAS 149198-47-0
(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate
CAS 149198-47-0C20H31NO4Si
(3R,4S)-3-(2-Methoxypropan-2-yloxy)-4-phenylazetidin-2-one chemical structure, C13H17NO3, CAS 160535-69-3
(3R,4S)-3-(2-Methoxypropan-2-yloxy)-4-phenylazetidin-2-one
CAS 160535-69-3C13H17NO3
3-(1-Ethoxyethoxy)-4-phenylazetidin-2-one chemical structure, C13H17NO3
3-(1-Ethoxyethoxy)-4-phenylazetidin-2-one
C13H17NO3
4-(3,4-Dichlorophenyl)azetidin-2-one chemical structure, C9H7Cl2NO, CAS 248607-62-7
4-(3,4-Dichlorophenyl)azetidin-2-one
CAS 248607-62-7C9H7Cl2NO
4-(4-Oxoazetidin-2-yl)benzonitrile chemical structure, C10H8N2O, CAS 777885-20-8
4-(4-Oxoazetidin-2-yl)benzonitrile
CAS 777885-20-8C10H8N2O
(4S)-1-Methyl-4-phenylazetidin-2-one chemical structure, C10H11NO, CAS 89617-58-3
(4S)-1-Methyl-4-phenylazetidin-2-one
CAS 89617-58-3C10H11NO
tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate chemical structure, C18H25NO5, CAS 152089-12-8
tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
CAS 152089-12-8C18H25NO5
tert-Butyl 2-oxo-4-phenyl-3-((triethylsilyl)oxy)azetidine-1-carboxylate chemical structure, C20H31NO4Si, CAS 914224-36-5
tert-Butyl 2-oxo-4-phenyl-3-((triethylsilyl)oxy)azetidine-1-carboxylate
CAS 914224-36-5C20H31NO4Si
4-(4-Chlorophenyl)azetidin-2-one chemical structure, C9H8ClNO, CAS 21161-20-6
4-(4-Chlorophenyl)azetidin-2-one
CAS 21161-20-6C9H8ClNO
2-Azetidinone, 1,3-dimethyl-4-phenyl-, trans- chemical structure, C11H13NO, CAS 4458-60-0
2-Azetidinone, 1,3-dimethyl-4-phenyl-, trans-
CAS 4458-60-0C11H13NO
3-Ethyl-1-methyl-4-phenyl-2-azetidinone chemical structure, C12H15NO, CAS 39629-39-5
3-Ethyl-1-methyl-4-phenyl-2-azetidinone
CAS 39629-39-5C12H15NO
4-(2,3-Dihydroxy-4-methoxyphenyl)azetidin-2-one chemical structure, C10H11NO4, CAS 777885-71-9
4-(2,3-Dihydroxy-4-methoxyphenyl)azetidin-2-one
CAS 777885-71-9C10H11NO4