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Murcko scaffold

2-Benzofuranyl-4-morpholinylmethanone scaffold

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
16
With full pages
5
Scaffold SMILES

O=C(c1cc2ccccc2o1)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Benzofuranyl-4-morpholinylmethanone page
Murcko scaffold O=C(c1cc2ccccc2o1)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Morpholine, 4-((6,7-dimethoxy-3-methyl-2-benzofuranyl)carbonyl)- chemical structure, C16H19NO5, CAS 38304-79-9
Morpholine, 4-((6,7-dimethoxy-3-methyl-2-benzofuranyl)carbonyl)-
CAS 38304-79-9C16H19NO5
Morpholine, 4-((6,7-diethoxy-3-methyl-2-benzofuranyl)carbonyl)- chemical structure, C18H23NO5, CAS 40713-21-1
Morpholine, 4-((6,7-diethoxy-3-methyl-2-benzofuranyl)carbonyl)-
CAS 40713-21-1C18H23NO5
Morpholine, 4-((6,7-diethoxy-3-methyl-5-nitro-2-benzofuranyl)carbonyl)- chemical structure, C18H22N2O7, CAS 40713-22-2
Morpholine, 4-((6,7-diethoxy-3-methyl-5-nitro-2-benzofuranyl)carbonyl)-
CAS 40713-22-2C18H22N2O7
4-((3-Methyl-1-benzofuran-2-yl)carbonyl)morpholine chemical structure, C14H15NO3, CAS 92248-59-4
4-((3-Methyl-1-benzofuran-2-yl)carbonyl)morpholine
CAS 92248-59-4C14H15NO3
(2,6-Dimethylmorpholino)(3-methylbenzofuran-2-yl)methanone chemical structure, C16H19NO3, CAS 588674-74-2
(2,6-Dimethylmorpholino)(3-methylbenzofuran-2-yl)methanone
CAS 588674-74-2C16H19NO3
2-Benzofuranyl-4-morpholinylmethanone chemical structure, C13H13NO3, CAS 77509-76-3
2-Benzofuranyl-4-morpholinylmethanone
CAS 77509-76-3C13H13NO3
2-(Morpholine-4-carbonyl)-1-benzofuran-3-amine chemical structure, C13H14N2O3, CAS 871217-33-3
2-(Morpholine-4-carbonyl)-1-benzofuran-3-amine
CAS 871217-33-3C13H14N2O3
Morpholine, 4-[(5-hydroxy-6,7-dimethyl-2-benzofuranyl)carbonyl]- chemical structure, C15H17NO4, CAS 581807-31-0
Morpholine, 4-[(5-hydroxy-6,7-dimethyl-2-benzofuranyl)carbonyl]-
CAS 581807-31-0C15H17NO4
2,6-Dimethylmorpholin-4-yl 5-chlorobenzo[d]furan-2-yl ketone chemical structure, C15H16ClNO3, CAS 882308-56-7
2,6-Dimethylmorpholin-4-yl 5-chlorobenzo[d]furan-2-yl ketone
CAS 882308-56-7C15H16ClNO3
(2,6-Dimethylmorpholin-4-yl)-(5-ethoxy-3-methyl-1-benzofuran-2-yl)methanone chemical structure, C18H23NO4, CAS 923740-44-7
(2,6-Dimethylmorpholin-4-yl)-(5-ethoxy-3-methyl-1-benzofuran-2-yl)methanone
CAS 923740-44-7C18H23NO4
(4-(3-Bromopropoxy)-3-methylbenzofuran-2-yl)(morpholino)methanone chemical structure, C17H20BrNO4, CAS 279231-44-6
(4-(3-Bromopropoxy)-3-methylbenzofuran-2-yl)(morpholino)methanone
CAS 279231-44-6C17H20BrNO4
(7-Ethoxybenzofuran-2-yl)(morpholino)methanone chemical structure, C15H17NO4, CAS 921825-32-3
(7-Ethoxybenzofuran-2-yl)(morpholino)methanone
CAS 921825-32-3C15H17NO4
(3-(Hydroxymethyl)morpholino)(7-methoxybenzofuran-2-yl)methanone chemical structure, C15H17NO5, CAS 1421445-62-6
(3-(Hydroxymethyl)morpholino)(7-methoxybenzofuran-2-yl)methanone
CAS 1421445-62-6C15H17NO5
(3-(((2-Hydroxyethyl)(methyl)amino)methyl)morpholino)(7-methoxybenzofuran-2-yl)methanone formate chemical structure, C19H26N2O7, CAS 1421513-92-9
(3-(((2-Hydroxyethyl)(methyl)amino)methyl)morpholino)(7-methoxybenzofuran-2-yl)methanone formate
CAS 1421513-92-9C19H26N2O7
Benzofuran-2-yl(3-((dimethylamino)methyl)morpholino)methanone formate chemical structure, C17H22N2O5, CAS 1421453-42-0
Benzofuran-2-yl(3-((dimethylamino)methyl)morpholino)methanone formate
CAS 1421453-42-0C17H22N2O5
(3-Amino-7-methoxybenzofuran-2-yl)(morpholino)methanone chemical structure, C14H16N2O4, CAS 1795296-88-6
(3-Amino-7-methoxybenzofuran-2-yl)(morpholino)methanone
CAS 1795296-88-6C14H16N2O4