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Murcko scaffold

Ring system with 4 rings and 24 atoms

586 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
586
With full pages
5
Scaffold SMILES

O=C(NCC1CCCC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC1CCCC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 586 chemicals

(AlphaS)-alpha-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]cyclopentaneacetic acid chemical structure, C22H23NO4, CAS 220497-61-0
(AlphaS)-alpha-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]cyclopentaneacetic acid
CAS 220497-61-0C22H23NO4
Fmoc-1-aminomethyl-cyclopentane carboxylic acid chemical structure, C22H23NO4, CAS 946727-65-7
Fmoc-1-aminomethyl-cyclopentane carboxylic acid
CAS 946727-65-7C22H23NO4
a-(N-Fmoc-N-methylamino)cyclopentaneacetic acid chemical structure, C23H25NO4, CAS 1700533-56-7
a-(N-Fmoc-N-methylamino)cyclopentaneacetic acid
CAS 1700533-56-7C23H25NO4
3-Cyclopentyl-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid chemical structure, C23H25NO4, CAS 954225-72-0
3-Cyclopentyl-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid
CAS 954225-72-0C23H25NO4
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-2-cyclopentylacetic acid chemical structure, C23H25NO4, CAS 187475-29-2
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-2-cyclopentylacetic acid
CAS 187475-29-2C23H25NO4
N-alpha-(9-Fluorenylmethyloxycarbonyl)-D-beta-cyclopentylglycine chemical structure, C22H23NO4, CAS 136555-16-3
N-alpha-(9-Fluorenylmethyloxycarbonyl)-D-beta-cyclopentylglycine
CAS 136555-16-3C22H23NO4
rac-(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopentane-1-carboxylic acid chemical structure, C22H23NO4, CAS 1932266-28-8
rac-(1R,2S)-2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopentane-1-carboxylic acid
CAS 1932266-28-8C22H23NO4
(9H-Fluoren-9-yl)methyl N-[(1-hydroxycyclopentyl)methyl]carbamate chemical structure, C21H23NO3, CAS 1490183-90-8
(9H-Fluoren-9-yl)methyl N-[(1-hydroxycyclopentyl)methyl]carbamate
CAS 1490183-90-8C21H23NO3
(9H-Fluoren-9-yl)methyl N-[(2-hydroxycyclopentyl)methyl]carbamate chemical structure, C21H23NO3, CAS 1478930-06-1
(9H-Fluoren-9-yl)methyl N-[(2-hydroxycyclopentyl)methyl]carbamate
CAS 1478930-06-1C21H23NO3
2-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclopentane-1-carboxylic acid chemical structure, C22H23NO4, CAS 1481412-58-1
2-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)cyclopentane-1-carboxylic acid
CAS 1481412-58-1C22H23NO4
(3R)-3-Cyclopentyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H25NO4, CAS 1260590-42-8
(3R)-3-Cyclopentyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1260590-42-8C23H25NO4
2-Cyclopentyl-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid chemical structure, C22H23NO4, CAS 1276562-78-7
2-Cyclopentyl-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid
CAS 1276562-78-7C22H23NO4
(3s)-3-Cyclopentyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid chemical structure, C23H25NO4, CAS 1260609-14-0
(3s)-3-Cyclopentyl-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
CAS 1260609-14-0C23H25NO4
Methyl (2S)-2-cyclopentyl-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetate chemical structure, C23H25NO4, CAS 1820580-47-9
Methyl (2S)-2-cyclopentyl-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetate
CAS 1820580-47-9C23H25NO4
(9H-Fluoren-9-yl)methyl N-[(3-hydroxycyclopentyl)methyl]carbamate chemical structure, C21H23NO3, CAS 1692240-95-1
(9H-Fluoren-9-yl)methyl N-[(3-hydroxycyclopentyl)methyl]carbamate
CAS 1692240-95-1C21H23NO3
(9H-Fluoren-9-yl)methyl N-[(1-hydroxycyclopentyl)methyl]-N-methylcarbamate chemical structure, C22H25NO3, CAS 1603172-94-6
(9H-Fluoren-9-yl)methyl N-[(1-hydroxycyclopentyl)methyl]-N-methylcarbamate
CAS 1603172-94-6C22H25NO3
(9H-Fluoren-9-yl)methyl N-{[1-(hydroxymethyl)cyclopentyl]methyl}carbamate chemical structure, C22H25NO3, CAS 1552859-84-3
(9H-Fluoren-9-yl)methyl N-{[1-(hydroxymethyl)cyclopentyl]methyl}carbamate
CAS 1552859-84-3C22H25NO3
(9H-Fluoren-9-yl)methyl N-[(1-hydroxy-2-methylcyclopentyl)methyl]carbamate chemical structure, C22H25NO3, CAS 1881925-44-5
(9H-Fluoren-9-yl)methyl N-[(1-hydroxy-2-methylcyclopentyl)methyl]carbamate
CAS 1881925-44-5C22H25NO3
(9H-Fluoren-9-yl)methyl N-(1-cyclopentyl-2-hydroxyethyl)carbamate chemical structure, C22H25NO3, CAS 1851297-19-2
(9H-Fluoren-9-yl)methyl N-(1-cyclopentyl-2-hydroxyethyl)carbamate
CAS 1851297-19-2C22H25NO3
(1S,3R,4R)-3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-hydroxycyclopentane-1-carboxylic acid chemical structure, C22H23NO5, CAS 2140262-77-5
(1S,3R,4R)-3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-hydroxycyclopentane-1-carboxylic acid
CAS 2140262-77-5C22H23NO5
2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopentyl}acetic acid chemical structure, C23H25NO4, CAS 2095411-04-2
2-{1-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopentyl}acetic acid
CAS 2095411-04-2C23H25NO4
(1R,3S)-3-[(9H-Fluoren-9-ylmethoxycarbonylamino)methyl]-3-fluorocyclopentane-1-carboxylic acid chemical structure, C22H22FNO4, CAS 2361723-03-5
(1R,3S)-3-[(9H-Fluoren-9-ylmethoxycarbonylamino)methyl]-3-fluorocyclopentane-1-carboxylic acid
CAS 2361723-03-5C22H22FNO4
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(3,3-difluorocyclopentyl)acetic acid chemical structure, C22H21F2NO4, CAS 2138774-35-1
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(3,3-difluorocyclopentyl)acetic acid
CAS 2138774-35-1C22H21F2NO4
3-(2-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopentyl}acetamido)-2-methylbutanoic acid chemical structure, C28H34N2O5, CAS 2171810-00-5
3-(2-{3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopentyl}acetamido)-2-methylbutanoic acid
CAS 2171810-00-5C28H34N2O5