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Murcko scaffold

Ring system with 4 rings and 24 atoms

240 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
240
With full pages
4
Scaffold SMILES

O=C(NCc1ccn[nH]1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccn[nH]1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 240 chemicals

(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-pyrazol-5-yl)propanoic acid chemical structure, C22H21N3O4, CAS 1704981-10-1
(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-pyrazol-5-yl)propanoic acid
CAS 1704981-10-1C22H21N3O4
(3S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-pyrazol-5-yl)propanoic acid chemical structure, C22H21N3O4, CAS 1704966-93-7
(3S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-pyrazol-5-yl)propanoic acid
CAS 1704966-93-7C22H21N3O4
3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-pyrazol-5-yl)propanoic acid chemical structure, C22H21N3O4, CAS 1692228-06-0
3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-pyrazol-5-yl)propanoic acid
CAS 1692228-06-0C22H21N3O4
3-(1-Ethyl-1H-pyrazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H23N3O4, CAS 1702246-18-1
3-(1-Ethyl-1H-pyrazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1702246-18-1C23H23N3O4
(3S)-3-(1-Ethyl-1H-pyrazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H23N3O4, CAS 1704977-56-9
(3S)-3-(1-Ethyl-1H-pyrazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1704977-56-9C23H23N3O4
(3R)-3-(1-Ethyl-1H-pyrazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H23N3O4, CAS 1704969-42-5
(3R)-3-(1-Ethyl-1H-pyrazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1704969-42-5C23H23N3O4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-methyl-1H-pyrazol-5-yl)acetic acid chemical structure, C21H19N3O4, CAS 1998980-60-1
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-methyl-1H-pyrazol-5-yl)acetic acid
CAS 1998980-60-1C21H19N3O4
5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid chemical structure, C21H19N3O4, CAS 2137620-27-8
5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid
CAS 2137620-27-8C21H19N3O4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-methyl-1H-pyrazol-3-yl)acetic acid chemical structure, C21H19N3O4, CAS 2137513-06-3
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-methyl-1H-pyrazol-3-yl)acetic acid
CAS 2137513-06-3C21H19N3O4
3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazole-5-carboxylic acid chemical structure, C21H19N3O4, CAS 2137821-77-1
3-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazole-5-carboxylic acid
CAS 2137821-77-1C21H19N3O4
3-[(9H-Fluoren-9-ylmethoxycarbonylamino)methyl]-1-methylpyrazole-4-carboxylic acid chemical structure, C21H19N3O4, CAS 2138027-90-2
3-[(9H-Fluoren-9-ylmethoxycarbonylamino)methyl]-1-methylpyrazole-4-carboxylic acid
CAS 2138027-90-2C21H19N3O4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(4-iodo-1-methyl-1H-pyrazol-5-yl)acetic acid chemical structure, C21H18IN3O4, CAS 2137462-62-3
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(4-iodo-1-methyl-1H-pyrazol-5-yl)acetic acid
CAS 2137462-62-3C21H18IN3O4
2-(3-Bromo-1-methyl-1H-pyrazol-5-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetic acid chemical structure, C21H18BrN3O4, CAS 2137458-73-0
2-(3-Bromo-1-methyl-1H-pyrazol-5-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetic acid
CAS 2137458-73-0C21H18BrN3O4
3-(N-Ethyl-1-{3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-5-yl}formamido)propanoic acid chemical structure, C26H28N4O5, CAS 2172102-05-3
3-(N-Ethyl-1-{3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-5-yl}formamido)propanoic acid
CAS 2172102-05-3C26H28N4O5
(2S)-2-(1-{5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}-N-methylformamido)propanoic acid chemical structure, C25H26N4O5, CAS 2171159-73-0
(2S)-2-(1-{5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}-N-methylformamido)propanoic acid
CAS 2171159-73-0C25H26N4O5
(3R)-3-(3-Bromo-1-methyl-1H-pyrazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C22H20BrN3O4, CAS 1997446-89-5
(3R)-3-(3-Bromo-1-methyl-1H-pyrazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1997446-89-5C22H20BrN3O4
4-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-methyl-1H-pyrazol-5-yl)acetamido]-2-methylbutanoic acid chemical structure, C26H28N4O5, CAS 2171749-24-7
4-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-methyl-1H-pyrazol-5-yl)acetamido]-2-methylbutanoic acid
CAS 2171749-24-7C26H28N4O5
2-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-methyl-1H-pyrazol-5-yl)acetamido]butanoic acid chemical structure, C25H26N4O5, CAS 2171748-52-8
2-[2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-methyl-1H-pyrazol-5-yl)acetamido]butanoic acid
CAS 2171748-52-8C25H26N4O5
(2S)-2-({5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}formamido)-3-hydroxypropanoic acid chemical structure, C24H24N4O6, CAS 2171224-38-5
(2S)-2-({5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}formamido)-3-hydroxypropanoic acid
CAS 2171224-38-5C24H24N4O6
4-({5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}formamido)-2-methylbut-2-enoic acid chemical structure, C26H26N4O5, CAS 2172633-69-9
4-({5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}formamido)-2-methylbut-2-enoic acid
CAS 2172633-69-9C26H26N4O5
4-(1-{5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}-N-methylformamido)butanoic acid chemical structure, C26H28N4O5, CAS 2172515-84-1
4-(1-{5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}-N-methylformamido)butanoic acid
CAS 2172515-84-1C26H28N4O5
(2R)-2-({5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}formamido)-3-methylbutanoic acid chemical structure, C26H28N4O5, CAS 2171262-99-8
(2R)-2-({5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}formamido)-3-methylbutanoic acid
CAS 2171262-99-8C26H28N4O5
2-(1-{5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}-N-methylformamido)acetic acid chemical structure, C24H24N4O5, CAS 2171978-33-7
2-(1-{5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}-N-methylformamido)acetic acid
CAS 2171978-33-7C24H24N4O5
2-[({5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}formamido)oxy]acetic acid chemical structure, C23H22N4O6, CAS 2171807-74-0
2-[({5-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1-methyl-1H-pyrazol-4-yl}formamido)oxy]acetic acid
CAS 2171807-74-0C23H22N4O6