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Murcko scaffold

Ring system with 4 rings and 24 atoms

579 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 24
Chemicals: 579
With full pages: 8

Scaffold SMILES

O=C(NCc1nccs1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(NCc1nccs1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 579 chemicals

2-[(1S)-1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-1,3-thiazole-4-carboxylic acid chemical structure, C21H18N2O4S, CAS 741729-77-1

2-[(1S)-1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-1,3-thiazole-4-carboxylic acid

CAS 741729-77-1C₂₁H₁₈N₂O₄S

2-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)-1,3-thiazole-4-carboxylic acid chemical structure, C20H16N2O4S, CAS 182120-85-0

2-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)-1,3-thiazole-4-carboxylic acid

CAS 182120-85-0C₂₀H₁₆N₂O₄S

(S)-2-(1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylpropyl)thiazole-4-carboxylic acid chemical structure, C23H22N2O4S, CAS 668489-48-3

(S)-2-(1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylpropyl)thiazole-4-carboxylic acid

CAS 668489-48-3C₂₃H₂₂N₂O₄S

Fmoc-DL-(2-thiazoyl)glycine chemical structure, C20H16N2O4S, CAS 1219381-54-0

Fmoc-DL-(2-thiazoyl)glycine

CAS 1219381-54-0C₂₀H₁₆N₂O₄S

2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methyl-1,3-thiazole-5-carboxylic acid chemical structure, C21H18N2O4S, CAS 1340415-08-8

2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methyl-1,3-thiazole-5-carboxylic acid

CAS 1340415-08-8C₂₁H₁₈N₂O₄S

2-(1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-1,3-thiazole-4-carboxylic acid chemical structure, C21H18N2O4S, CAS 1518885-04-5

2-(1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-1,3-thiazole-4-carboxylic acid

CAS 1518885-04-5C₂₁H₁₈N₂O₄S

3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1,3-thiazol-2-yl)propanoic acid chemical structure, C21H18N2O4S, CAS 1693951-48-2

3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1,3-thiazol-2-yl)propanoic acid

CAS 1693951-48-2C₂₁H₁₈N₂O₄S

(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1,3-thiazol-2-yl)propanoic acid chemical structure, C21H18N2O4S, CAS 1704979-85-0

(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1,3-thiazol-2-yl)propanoic acid

CAS 1704979-85-0C₂₁H₁₈N₂O₄S

(3S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1,3-thiazol-2-yl)propanoic acid chemical structure, C21H18N2O4S, CAS 1704969-60-7

(3S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1,3-thiazol-2-yl)propanoic acid

CAS 1704969-60-7C₂₁H₁₈N₂O₄S

3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methyl-1,3-thiazol-2-yl)propanoic acid chemical structure, C22H20N2O4S, CAS 1702206-48-1

3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methyl-1,3-thiazol-2-yl)propanoic acid

CAS 1702206-48-1C₂₂H₂₀N₂O₄S

(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methyl-1,3-thiazol-2-yl)propanoic acid chemical structure, C22H20N2O4S, CAS 1704975-84-7

(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methyl-1,3-thiazol-2-yl)propanoic acid

CAS 1704975-84-7C₂₂H₂₀N₂O₄S

(3S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methyl-1,3-thiazol-2-yl)propanoic acid chemical structure, C22H20N2O4S, CAS 1704964-36-2

(3S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-methyl-1,3-thiazol-2-yl)propanoic acid

CAS 1704964-36-2C₂₂H₂₀N₂O₄S

3-(5-Chloro-1,3-thiazol-2-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H17ClN2O4S, CAS 1697042-63-9

3-(5-Chloro-1,3-thiazol-2-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid

CAS 1697042-63-9C₂₁H₁₇ClN₂O₄S

(3R)-3-(5-Chloro-1,3-thiazol-2-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H17ClN2O4S, CAS 1690049-97-8

(3R)-3-(5-Chloro-1,3-thiazol-2-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid

CAS 1690049-97-8C₂₁H₁₇ClN₂O₄S

(3S)-3-(5-Chloro-1,3-thiazol-2-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H17ClN2O4S, CAS 1690166-96-1

(3S)-3-(5-Chloro-1,3-thiazol-2-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid

CAS 1690166-96-1C₂₁H₁₇ClN₂O₄S

2-(1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-1,3-thiazole-5-carboxylic acid chemical structure, C21H18N2O4S, CAS 2138144-26-8

2-(1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-1,3-thiazole-5-carboxylic acid

CAS 2138144-26-8C₂₁H₁₈N₂O₄S

2-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)-5-methyl-1,3-thiazole-4-carboxylic acid chemical structure, C21H18N2O4S, CAS 2137710-89-3

2-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)-5-methyl-1,3-thiazole-4-carboxylic acid

CAS 2137710-89-3C₂₁H₁₈N₂O₄S

2-{2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methyl-1,3-thiazol-5-yl}acetic acid chemical structure, C22H20N2O4S, CAS 2137647-64-2

2-{2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methyl-1,3-thiazol-5-yl}acetic acid

CAS 2137647-64-2C₂₂H₂₀N₂O₄S

2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-4-methyl-1,3-thiazole-5-carboxylic acid chemical structure, C22H20N2O4S, CAS 2137787-63-2

2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-4-methyl-1,3-thiazole-5-carboxylic acid

CAS 2137787-63-2C₂₂H₂₀N₂O₄S

2-{2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,3-thiazol-4-yl}acetic acid chemical structure, C21H18N2O4S, CAS 2138189-66-7

2-{2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,3-thiazol-4-yl}acetic acid

CAS 2138189-66-7C₂₁H₁₈N₂O₄S

2-(4-Bromo-1,3-thiazol-2-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetic acid chemical structure, C20H15BrN2O4S, CAS 2137503-78-5

2-(4-Bromo-1,3-thiazol-2-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetic acid

CAS 2137503-78-5C₂₀H₁₅BrN₂O₄S

2-(1-{2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-5-methyl-1,3-thiazol-4-yl}-N-methylformamido)acetic acid chemical structure, C24H23N3O5S, CAS 2172223-29-7

2-(1-{2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-5-methyl-1,3-thiazol-4-yl}-N-methylformamido)acetic acid

CAS 2172223-29-7C₂₄H₂₃N₃O₅S

4-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,3-thiazol-4-yl}formamido)-2-hydroxybutanoic acid chemical structure, C24H23N3O6S, CAS 2172025-74-8

4-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,3-thiazol-4-yl}formamido)-2-hydroxybutanoic acid

CAS 2172025-74-8C₂₄H₂₃N₃O₆S

(3S)-3-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methyl-1,3-thiazol-5-yl}formamido)pentanoic acid chemical structure, C26H27N3O5S, CAS 2171160-69-1

(3S)-3-({2-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methyl-1,3-thiazol-5-yl}formamido)pentanoic acid

CAS 2171160-69-1C₂₆H₂₇N₃O₅S