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Murcko scaffold

Ring system with 4 rings and 24 atoms

99 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
99
With full pages
2
Scaffold SMILES

O=C(NCc1c[nH]nn1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1c[nH]nn1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 99 chemicals

2-(4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid chemical structure, C20H18N4O4, CAS 943918-76-1
2-(4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid
CAS 943918-76-1C20H18N4O4
4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)-1-methyl-1H-1,2,3-triazole-5-carboxylic acid chemical structure, C20H18N4O4, CAS 2219408-47-4
4-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)-1-methyl-1H-1,2,3-triazole-5-carboxylic acid
CAS 2219408-47-4C20H18N4O4
5-{[(Butan-2-yl)({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]methyl}-1H-1,2,3-triazole-4-carboxylic acid chemical structure, C23H24N4O4, CAS 2137715-43-4
5-{[(Butan-2-yl)({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]methyl}-1H-1,2,3-triazole-4-carboxylic acid
CAS 2137715-43-4C23H24N4O4
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-(2-hydroxyethyl)acetamido)acetic acid chemical structure, C24H25N5O6, CAS 2172462-22-3
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-(2-hydroxyethyl)acetamido)acetic acid
CAS 2172462-22-3C24H25N5O6
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)propanoic acid chemical structure, C24H25N5O5, CAS 2172376-19-9
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)propanoic acid
CAS 2172376-19-9C24H25N5O5
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-methylpropanoic acid chemical structure, C24H25N5O5, CAS 2172523-47-4
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-methylpropanoic acid
CAS 2172523-47-4C24H25N5O5
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)butanoic acid chemical structure, C24H25N5O5, CAS 2172522-98-2
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)butanoic acid
CAS 2172522-98-2C24H25N5O5
(2S)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)propanoic acid chemical structure, C23H23N5O5, CAS 2171280-11-6
(2S)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)propanoic acid
CAS 2171280-11-6C23H23N5O5
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)butanoic acid chemical structure, C25H27N5O5, CAS 2172524-30-8
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)butanoic acid
CAS 2172524-30-8C25H27N5O5
(3S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-1,2,3-triazol-4-yl)propanoic acid chemical structure, C21H20N4O4, CAS 1867431-20-6
(3S)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-1,2,3-triazol-4-yl)propanoic acid
CAS 1867431-20-6C21H20N4O4
(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-1,2,3-triazol-4-yl)propanoic acid chemical structure, C21H20N4O4, CAS 1867586-89-7
(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1-methyl-1H-1,2,3-triazol-4-yl)propanoic acid
CAS 1867586-89-7C21H20N4O4
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)propanoic acid chemical structure, C23H23N5O5, CAS 2172029-52-4
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)propanoic acid
CAS 2172029-52-4C23H23N5O5
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-3-hydroxybutanoic acid chemical structure, C24H25N5O6, CAS 2172048-89-2
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-3-hydroxybutanoic acid
CAS 2172048-89-2C24H25N5O6
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-(prop-2-en-1-yl)acetamido)acetic acid chemical structure, C25H25N5O5, CAS 2172178-00-4
2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-(prop-2-en-1-yl)acetamido)acetic acid
CAS 2172178-00-4C25H25N5O5
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-methylbutanoic acid chemical structure, C25H27N5O5, CAS 2172050-06-3
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-methylbutanoic acid
CAS 2172050-06-3C25H27N5O5
(2R)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-3-methylbutanoic acid chemical structure, C25H27N5O5, CAS 2171249-32-2
(2R)-2-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-3-methylbutanoic acid
CAS 2171249-32-2C25H27N5O5
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)-2-methylpropanoic acid chemical structure, C25H27N5O5, CAS 2172396-29-9
3-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}-N-methylacetamido)-2-methylpropanoic acid
CAS 2172396-29-9C25H27N5O5
(2S)-4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-hydroxybutanoic acid chemical structure, C24H25N5O6, CAS 2171221-11-5
(2S)-4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-hydroxybutanoic acid
CAS 2171221-11-5C24H25N5O6
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-hydroxybutanoic acid chemical structure, C24H25N5O6, CAS 2172227-63-1
4-(2-{4-[({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetamido)-2-hydroxybutanoic acid
CAS 2172227-63-1C24H25N5O6
3-(1-Ethyl-1H-1,2,3-triazol-4-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C22H22N4O4, CAS 2172438-93-4
3-(1-Ethyl-1H-1,2,3-triazol-4-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2172438-93-4C22H22N4O4
(3R)-3-(1-Ethyl-1H-1,2,3-triazol-4-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C22H22N4O4, CAS 2171263-67-3
(3R)-3-(1-Ethyl-1H-1,2,3-triazol-4-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2171263-67-3C22H22N4O4
(3S)-3-(4-Bromo-1-methyl-1H-1,2,3-triazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H19BrN4O4, CAS 1842577-77-8
(3S)-3-(4-Bromo-1-methyl-1H-1,2,3-triazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1842577-77-8C21H19BrN4O4
3-(4-Bromo-1-methyl-1H-1,2,3-triazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C21H19BrN4O4, CAS 1881621-69-7
3-(4-Bromo-1-methyl-1H-1,2,3-triazol-5-yl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1881621-69-7C21H19BrN4O4
(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(2-methyl-2H-1,2,3-triazol-4-yl)propanoic acid chemical structure, C21H20N4O4, CAS 1867200-06-3
(3R)-3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(2-methyl-2H-1,2,3-triazol-4-yl)propanoic acid
CAS 1867200-06-3C21H20N4O4