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Murcko scaffold

2-(Benzenesulfonyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide scaffold

82 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
82
With full pages
12
Scaffold SMILES

O=C(CS(=O)(=O)c1ccccc1)Nc1nc(-c2ccccc2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Benzenesulfonyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide page
Murcko scaffold O=C(CS(=O)(=O)c1ccccc1)Nc1nc(-c2ccccc2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 82 chemicals

N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-[(3-methylphenyl)sulfonyl]acetamide chemical structure, C18H15ClN2O3S2, CAS 338959-67-4
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-[(3-methylphenyl)sulfonyl]acetamide
CAS 338959-67-4C18H15ClN2O3S2
2-(Benzenesulfonyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C17H14N2O3S2, CAS 827007-03-4
2-(Benzenesulfonyl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 827007-03-4C17H14N2O3S2
2-(Benzenesulfonyl)-N-(5-ethyl-4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C19H18N2O3S2, CAS 857497-74-6
2-(Benzenesulfonyl)-N-(5-ethyl-4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 857497-74-6C19H18N2O3S2
2-((4-Chlorophenyl)sulfonyl)-N-(4-phenylthiazol-2-yl)acetamide chemical structure, C17H13ClN2O3S2, CAS 338965-88-1
2-((4-Chlorophenyl)sulfonyl)-N-(4-phenylthiazol-2-yl)acetamide
CAS 338965-88-1C17H13ClN2O3S2
N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-2-(4-methylbenzenesulfonyl)acetamide chemical structure, C18H15FN2O3S2, CAS 892032-43-8
N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-2-(4-methylbenzenesulfonyl)acetamide
CAS 892032-43-8C18H15FN2O3S2
2-(Benzenesulfonyl)-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]acetamide chemical structure, C17H13ClN2O3S2, CAS 338966-01-1
2-(Benzenesulfonyl)-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]acetamide
CAS 338966-01-1C17H13ClN2O3S2
2-[(4-Methylphenyl)sulfonyl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C18H16N2O3S2, CAS 338965-86-9
2-[(4-Methylphenyl)sulfonyl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 338965-86-9C18H16N2O3S2
2-[(3-Methylphenyl)sulfonyl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C18H16N2O3S2, CAS 338965-95-0
2-[(3-Methylphenyl)sulfonyl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 338965-95-0C18H16N2O3S2
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-[(2,3-dichlorophenyl)sulfonyl]acetamide chemical structure, C17H11Cl3N2O3S2, CAS 338965-87-0
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-[(2,3-dichlorophenyl)sulfonyl]acetamide
CAS 338965-87-0C17H11Cl3N2O3S2
N-(4-(4-Methoxyphenyl)thiazol-2-yl)-2-tosylacetamide chemical structure, C19H18N2O4S2, CAS 892039-69-9
N-(4-(4-Methoxyphenyl)thiazol-2-yl)-2-tosylacetamide
CAS 892039-69-9C19H18N2O4S2
2-(Benzenesulfonyl)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]acetamide chemical structure, C18H16N2O4S2, CAS 892039-54-2
2-(Benzenesulfonyl)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]acetamide
CAS 892039-54-2C18H16N2O4S2
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-[(4-methylphenyl)sulfonyl]acetamide chemical structure, C18H15ClN2O3S2, CAS 767323-37-5
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-[(4-methylphenyl)sulfonyl]acetamide
CAS 767323-37-5C18H15ClN2O3S2
2-(Benzenesulfonyl)-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]acetamide chemical structure, C18H16N2O3S2, CAS 892030-17-0
2-(Benzenesulfonyl)-N-[4-(4-methylphenyl)-1,3-thiazol-2-yl]acetamide
CAS 892030-17-0C18H16N2O3S2
2-(4-Bromophenyl)sulfonyl-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]acetamide chemical structure, C17H12BrClN2O3S2, CAS 338966-06-6
2-(4-Bromophenyl)sulfonyl-N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]acetamide
CAS 338966-06-6C17H12BrClN2O3S2
2-(Benzenesulfonyl)-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetamide chemical structure, C17H13FN2O3S2, CAS 767323-36-4
2-(Benzenesulfonyl)-N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]acetamide
CAS 767323-36-4C17H13FN2O3S2
N-(4-(4-Methoxyphenyl)-5-methylthiazol-2-yl)-2-tosylacetamide chemical structure, C20H20N2O4S2, CAS 895451-11-3
N-(4-(4-Methoxyphenyl)-5-methylthiazol-2-yl)-2-tosylacetamide
CAS 895451-11-3C20H20N2O4S2
N-(5-Acetyl-4-phenyl-1,3-thiazol-2-yl)-2-(benzenesulfonyl)acetamide chemical structure, C19H16N2O4S2, CAS 895455-97-7
N-(5-Acetyl-4-phenyl-1,3-thiazol-2-yl)-2-(benzenesulfonyl)acetamide
CAS 895455-97-7C19H16N2O4S2
2-(Benzenesulfonyl)-N-[4-(4-propoxyphenyl)-1,3-thiazol-2-yl]acetamide chemical structure, C20H20N2O4S2, CAS 895456-03-8
2-(Benzenesulfonyl)-N-[4-(4-propoxyphenyl)-1,3-thiazol-2-yl]acetamide
CAS 895456-03-8C20H20N2O4S2
2-(Benzenesulfonyl)-N-[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]acetamide chemical structure, C19H18N2O4S2, CAS 898427-58-2
2-(Benzenesulfonyl)-N-[4-(4-ethoxyphenyl)-1,3-thiazol-2-yl]acetamide
CAS 898427-58-2C19H18N2O4S2
2-(Benzenesulfonyl)-N-[4-(4-methoxyphenyl)-5-methyl-1,3-thiazol-2-yl]acetamide chemical structure, C19H18N2O4S2, CAS 895461-42-4
2-(Benzenesulfonyl)-N-[4-(4-methoxyphenyl)-5-methyl-1,3-thiazol-2-yl]acetamide
CAS 895461-42-4C19H18N2O4S2
2-(Benzenesulfonyl)-N-[4-(4-ethoxyphenyl)-5-methyl-1,3-thiazol-2-yl]acetamide chemical structure, C20H20N2O4S2, CAS 895461-49-1
2-(Benzenesulfonyl)-N-[4-(4-ethoxyphenyl)-5-methyl-1,3-thiazol-2-yl]acetamide
CAS 895461-49-1C20H20N2O4S2
2-((4-Fluorophenyl)sulfonyl)-N-(4-(p-tolyl)thiazol-2-yl)acetamide chemical structure, C18H15FN2O3S2, CAS 895469-73-5
2-((4-Fluorophenyl)sulfonyl)-N-(4-(p-tolyl)thiazol-2-yl)acetamide
CAS 895469-73-5C18H15FN2O3S2
2-((4-Fluorophenyl)sulfonyl)-N-(4-(4-methoxyphenyl)thiazol-2-yl)acetamide chemical structure, C18H15FN2O4S2, CAS 895469-86-0
2-((4-Fluorophenyl)sulfonyl)-N-(4-(4-methoxyphenyl)thiazol-2-yl)acetamide
CAS 895469-86-0C18H15FN2O4S2
N-(4-(2,5-Dimethylphenyl)thiazol-2-yl)-2-tosylacetamide chemical structure, C20H20N2O3S2, CAS 895443-96-6
N-(4-(2,5-Dimethylphenyl)thiazol-2-yl)-2-tosylacetamide
CAS 895443-96-6C20H20N2O3S2