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Murcko scaffold

N-(4-Phenylthiazol-2-yl)-2-(piperidin-1-yl)acetamide scaffold

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
13
With full pages
8
Scaffold SMILES

O=C(CN1CCCCC1)Nc1nc(-c2ccccc2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(4-Phenylthiazol-2-yl)-2-(piperidin-1-yl)acetamide page
Murcko scaffold O=C(CN1CCCCC1)Nc1nc(-c2ccccc2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-piperidinoacetamide chemical structure, C16H18ClN3OS, CAS 101436-55-9
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-piperidinoacetamide
CAS 101436-55-9C16H18ClN3OS
1-[(4-Phenyl-thiazol-2-ylcarbamoyl)-methyl]-piperidine-4-carboxylic acid amide chemical structure, C17H20N4O2S, CAS 352660-85-6
1-[(4-Phenyl-thiazol-2-ylcarbamoyl)-methyl]-piperidine-4-carboxylic acid amide
CAS 352660-85-6C17H20N4O2S
2-(4-Methylpiperidin-1-yl)-N-(4-phenylthiazol-2-yl)acetamide chemical structure, C17H21N3OS, CAS 373617-51-7
2-(4-Methylpiperidin-1-yl)-N-(4-phenylthiazol-2-yl)acetamide
CAS 373617-51-7C17H21N3OS
N-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-2-piperidin-1-ylacetamide chemical structure, C16H18BrN3OS, CAS 103041-76-5
N-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-2-piperidin-1-ylacetamide
CAS 103041-76-5C16H18BrN3OS
N-(4-Phenylthiazol-2-yl)-2-(piperidin-1-yl)acetamide chemical structure, C16H19N3OS, CAS 66179-98-4
N-(4-Phenylthiazol-2-yl)-2-(piperidin-1-yl)acetamide
CAS 66179-98-4C16H19N3OS
N-(4-Phenyl-1,3-thiazol-2-yl)-2-piperidin-1-yl-N-prop-2-enylacetamide chemical structure, C19H23N3OS, CAS 721897-39-8
N-(4-Phenyl-1,3-thiazol-2-yl)-2-piperidin-1-yl-N-prop-2-enylacetamide
CAS 721897-39-8C19H23N3OS
2-(2-Methylpiperidin-1-yl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C17H21N3OS, CAS 489396-34-1
2-(2-Methylpiperidin-1-yl)-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 489396-34-1C17H21N3OS
1-[(4-p-Tolyl-thiazol-2-ylcarbamoyl)-methyl]-piperidine-4-carboxylic acid amide chemical structure, C18H22N4O2S, CAS 878440-41-6
1-[(4-p-Tolyl-thiazol-2-ylcarbamoyl)-methyl]-piperidine-4-carboxylic acid amide
CAS 878440-41-6C18H22N4O2S
Ethyl 1-{2-oxo-2-[(4-phenyl-1,3-thiazol-2-yl)amino]ethyl}piperidine-3-carboxylate chemical structure, C19H23N3O3S, CAS 879618-47-0
Ethyl 1-{2-oxo-2-[(4-phenyl-1,3-thiazol-2-yl)amino]ethyl}piperidine-3-carboxylate
CAS 879618-47-0C19H23N3O3S
N-[4-(3,4-Difluorophenyl)-1,3-thiazol-2-yl]-2-piperidin-1-ylacetamide chemical structure, C16H17F2N3OS, CAS 880274-13-5
N-[4-(3,4-Difluorophenyl)-1,3-thiazol-2-yl]-2-piperidin-1-ylacetamide
CAS 880274-13-5C16H17F2N3OS
N-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-2-(3-methylpiperidin-1-yl)acetamide chemical structure, C18H23N3OS, CAS 936820-36-9
N-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-2-(3-methylpiperidin-1-yl)acetamide
CAS 936820-36-9C18H23N3OS
N-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-2-(4-methylpiperidin-1-yl)acetamide chemical structure, C18H23N3OS, CAS 947009-08-7
N-(5-Methyl-4-phenyl-1,3-thiazol-2-yl)-2-(4-methylpiperidin-1-yl)acetamide
CAS 947009-08-7C18H23N3OS
2-[4,4-Difluoro-3-(hydroxymethyl)piperidin-1-yl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide chemical structure, C17H19F2N3O2S, CAS 2419285-95-1
2-[4,4-Difluoro-3-(hydroxymethyl)piperidin-1-yl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide
CAS 2419285-95-1C17H19F2N3O2S