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Murcko scaffold

Ring system with 3 rings and 21 atoms

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
27
With full pages
4
Scaffold SMILES

S=C(Nc1ccccc1)N1CCC(N2CCCCC2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=C(Nc1ccccc1)N1CCC(N2CCCCC2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

1'-[(2,3-Dimethylphenyl)carbamothioyl]-1,4'-bipiperidine-4'-carboxamide chemical structure, C20H30N4OS, CAS 444286-90-2
1'-[(2,3-Dimethylphenyl)carbamothioyl]-1,4'-bipiperidine-4'-carboxamide
CAS 444286-90-2C20H30N4OS
1-[(2,4-Dimethylphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C20H30N4OS, CAS 433256-19-0
1-[(2,4-Dimethylphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 433256-19-0C20H30N4OS
1'-[(2,5-Dimethylphenyl)carbamothioyl]-1,4'-bipiperidine-4'-carboxamide chemical structure, C20H30N4OS, CAS 433315-41-4
1'-[(2,5-Dimethylphenyl)carbamothioyl]-1,4'-bipiperidine-4'-carboxamide
CAS 433315-41-4C20H30N4OS
1'-[(3,5-Dimethylphenyl)carbamothioyl]-1,4'-bipiperidine-4'-carboxamide chemical structure, C20H30N4OS, CAS 433260-41-4
1'-[(3,5-Dimethylphenyl)carbamothioyl]-1,4'-bipiperidine-4'-carboxamide
CAS 433260-41-4C20H30N4OS
1'-[(4-Chloro-2-methylphenyl)carbamothioyl]-1,4'-bipiperidine-4'-carboxamide chemical structure, C19H27ClN4OS, CAS 433259-38-2
1'-[(4-Chloro-2-methylphenyl)carbamothioyl]-1,4'-bipiperidine-4'-carboxamide
CAS 433259-38-2C19H27ClN4OS
Ethyl 4-{[(4-carbamoyl-4-piperidylpiperidyl)thioxomethyl]amino}benzoate chemical structure, C21H30N4O3S, CAS 433255-44-8
Ethyl 4-{[(4-carbamoyl-4-piperidylpiperidyl)thioxomethyl]amino}benzoate
CAS 433255-44-8C21H30N4O3S
1-[(2,4-Dimethoxyphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C20H30N4O3S, CAS 433309-93-4
1-[(2,4-Dimethoxyphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 433309-93-4C20H30N4O3S
1-{[(2,5-Dimethoxyphenyl)amino]thioxomethyl}-4-piperidylpiperidine-4-carboxami de chemical structure, C20H30N4O3S, CAS 433255-08-4
1-{[(2,5-Dimethoxyphenyl)amino]thioxomethyl}-4-piperidylpiperidine-4-carboxami de
CAS 433255-08-4C20H30N4O3S
1-[(4-Chloro-2,5-dimethoxyphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C20H29ClN4O3S, CAS 664968-99-4
1-[(4-Chloro-2,5-dimethoxyphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 664968-99-4C20H29ClN4O3S
Methyl 2-[4-[(4-carbamoyl-4-piperidin-1-ylpiperidine-1-carbothioyl)amino]phenyl]acetate chemical structure, C21H30N4O3S, CAS 516457-97-9
Methyl 2-[4-[(4-carbamoyl-4-piperidin-1-ylpiperidine-1-carbothioyl)amino]phenyl]acetate
CAS 516457-97-9C21H30N4O3S
1'-[[(4-Ethoxyphenyl)amino]thioxomethyl][1,4'-bipiperidine]-4'-carboxamide chemical structure, C20H30N4O2S, CAS 443291-80-3
1'-[[(4-Ethoxyphenyl)amino]thioxomethyl][1,4'-bipiperidine]-4'-carboxamide
CAS 443291-80-3C20H30N4O2S
1-{[(4-Fluorophenyl)amino]thioxomethyl}-4-piperidylpiperidine-4-carboxamide chemical structure, C18H25FN4OS, CAS 443290-29-7
1-{[(4-Fluorophenyl)amino]thioxomethyl}-4-piperidylpiperidine-4-carboxamide
CAS 443290-29-7C18H25FN4OS
1'-{[(3-Chloro-2-methylphenyl)amino]carbonothioyl}-1,4'-bipiperidine-4'-carboxamide chemical structure, C19H27ClN4OS, CAS 433312-39-1
1'-{[(3-Chloro-2-methylphenyl)amino]carbonothioyl}-1,4'-bipiperidine-4'-carboxamide
CAS 433312-39-1C19H27ClN4OS
1-[(3,5-Dimethoxyphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C20H30N4O3S, CAS 433324-08-4
1-[(3,5-Dimethoxyphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 433324-08-4C20H30N4O3S
1-[(4-Methoxyphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C19H28N4O2S, CAS 333439-82-0
1-[(4-Methoxyphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 333439-82-0C19H28N4O2S
1-[(4-Chlorophenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C18H25ClN4OS, CAS 383902-67-8
1-[(4-Chlorophenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 383902-67-8C18H25ClN4OS
1-{[(2-Methoxyphenyl)amino]thioxomethyl}-4-piperidylpiperidine-4-carboxamide chemical structure, C19H28N4O2S, CAS 516457-98-0
1-{[(2-Methoxyphenyl)amino]thioxomethyl}-4-piperidylpiperidine-4-carboxamide
CAS 516457-98-0C19H28N4O2S
1-[(4-Acetylphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C20H28N4O2S, CAS 708279-97-4
1-[(4-Acetylphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 708279-97-4C20H28N4O2S
1-[(3-Chloro-4-fluorophenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C18H24ClFN4OS, CAS 708280-19-7
1-[(3-Chloro-4-fluorophenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 708280-19-7C18H24ClFN4OS
1-[(4-Butylphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide chemical structure, C22H34N4OS, CAS 627063-49-4
1-[(4-Butylphenyl)carbamothioyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS 627063-49-4C22H34N4OS
4-Piperidin-1-yl-1-[(4-sulfamoylphenyl)carbamothioyl]piperidine-4-carboxamide chemical structure, C18H27N5O3S2, CAS 664969-57-7
4-Piperidin-1-yl-1-[(4-sulfamoylphenyl)carbamothioyl]piperidine-4-carboxamide
CAS 664969-57-7C18H27N5O3S2
4-Piperidin-1-yl-1-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperidine-4-carboxamide chemical structure, C19H25F3N4OS, CAS 522637-06-5
4-Piperidin-1-yl-1-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperidine-4-carboxamide
CAS 522637-06-5C19H25F3N4OS
Dimethyl 5-{[(4'-carbamoyl-1,4'-bipiperidin-1'-yl)carbonothioyl]amino}benzene-1,3-dicarboxylate chemical structure, C22H30N4O5S, CAS 709002-98-2
Dimethyl 5-{[(4'-carbamoyl-1,4'-bipiperidin-1'-yl)carbonothioyl]amino}benzene-1,3-dicarboxylate
CAS 709002-98-2C22H30N4O5S
Methyl 2-[(4-carbamoyl-4-piperidin-1-ylpiperidine-1-carbothioyl)amino]-4,5-dimethoxybenzoate chemical structure, C22H32N4O5S, CAS 717832-07-0
Methyl 2-[(4-carbamoyl-4-piperidin-1-ylpiperidine-1-carbothioyl)amino]-4,5-dimethoxybenzoate
CAS 717832-07-0C22H32N4O5S