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Murcko scaffold

Ring system with 2 rings and 19 atoms

16 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
16
With full pages
5
Scaffold SMILES

O=C(NN=Cc1cccs1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1cccs1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

N-(2,5-Dichlorophenyl)-N'-(thiophen-2-ylmethylideneamino)oxamide chemical structure, C13H9Cl2N3O2S
N-(2,5-Dichlorophenyl)-N'-(thiophen-2-ylmethylideneamino)oxamide
C13H9Cl2N3O2S
N-(4-Acetamidophenyl)-N'-(1-thiophen-2-ylethylideneamino)oxamide chemical structure, C16H16N4O3S
N-(4-Acetamidophenyl)-N'-(1-thiophen-2-ylethylideneamino)oxamide
C16H16N4O3S
N-(3-Chlorophenyl)-2-oxo-2-[2-(2-thienylmethylene)hydrazino]acetamide chemical structure, C13H10ClN3O2S, CAS 331264-44-9
N-(3-Chlorophenyl)-2-oxo-2-[2-(2-thienylmethylene)hydrazino]acetamide
CAS 331264-44-9C13H10ClN3O2S
N-(3-Bromophenyl)-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide chemical structure, C13H10BrN3O2S, CAS 330990-77-7
N-(3-Bromophenyl)-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide
CAS 330990-77-7C13H10BrN3O2S
N-Phenyl-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide chemical structure, C13H11N3O2S, CAS 5545-77-7
N-Phenyl-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide
CAS 5545-77-7C13H11N3O2S
N-(2-Methoxyphenyl)-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide chemical structure, C14H13N3O3S, CAS 352012-72-7
N-(2-Methoxyphenyl)-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide
CAS 352012-72-7C14H13N3O3S
N-(3,4-Dimethylphenyl)-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide chemical structure, C15H15N3O2S, CAS 352004-87-6
N-(3,4-Dimethylphenyl)-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide
CAS 352004-87-6C15H15N3O2S
N-(4-Methylphenyl)-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide chemical structure, C14H13N3O2S, CAS 352645-06-8
N-(4-Methylphenyl)-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide
CAS 352645-06-8C14H13N3O2S
N-(2,5-Dichlorophenyl)-2-oxo-2-[(2Z)-2-(2-thienylmethylene)hydrazino]acetamide chemical structure, C13H9Cl2N3O2S, CAS 606486-07-1
N-(2,5-Dichlorophenyl)-2-oxo-2-[(2Z)-2-(2-thienylmethylene)hydrazino]acetamide
CAS 606486-07-1C13H9Cl2N3O2S
N-(4-Ethylphenyl)-2-oxo-2-(2-(2-thienylmethylene)hydrazino)acetamide chemical structure, C15H15N3O2S, CAS 327992-53-0
N-(4-Ethylphenyl)-2-oxo-2-(2-(2-thienylmethylene)hydrazino)acetamide
CAS 327992-53-0C15H15N3O2S
N-(4-Methoxyphenyl)-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide chemical structure, C14H13N3O3S, CAS 352012-84-1
N-(4-Methoxyphenyl)-N'-[(E)-thiophen-2-ylmethylideneamino]oxamide
CAS 352012-84-1C14H13N3O3S
N-(4-Acetamidophenyl)-2-oxo-2-{(2Z)-2-[1-(2-thienyl)ethylidene]hydrazino}acetamide chemical structure, C16H16N4O3S, CAS 606483-40-3
N-(4-Acetamidophenyl)-2-oxo-2-{(2Z)-2-[1-(2-thienyl)ethylidene]hydrazino}acetamide
CAS 606483-40-3C16H16N4O3S
N-(5-Chloro-2-methylphenyl)-2-oxo-2-[2-(2-thienylmethylene)hydrazino]acetamide chemical structure, C14H12ClN3O2S, CAS 360069-99-4
N-(5-Chloro-2-methylphenyl)-2-oxo-2-[2-(2-thienylmethylene)hydrazino]acetamide
CAS 360069-99-4C14H12ClN3O2S
N-(3,4-Dichlorophenyl)-2-oxo-2-(2-(2-thienylmethylene)hydrazino)acetamide chemical structure, C13H9Cl2N3O2S, CAS 350795-20-9
N-(3,4-Dichlorophenyl)-2-oxo-2-(2-(2-thienylmethylene)hydrazino)acetamide
CAS 350795-20-9C13H9Cl2N3O2S
N-(2,3-Dichlorophenyl)-2-oxo-2-(2-(2-thienylmethylene)hydrazino)acetamide chemical structure, C13H9Cl2N3O2S, CAS 328002-28-4
N-(2,3-Dichlorophenyl)-2-oxo-2-(2-(2-thienylmethylene)hydrazino)acetamide
CAS 328002-28-4C13H9Cl2N3O2S
N-(3-Methoxyphenyl)-2-oxo-2-(2-(2-thienylmethylene)hydrazino)acetamide chemical structure, C14H13N3O3S, CAS 359447-60-2
N-(3-Methoxyphenyl)-2-oxo-2-(2-(2-thienylmethylene)hydrazino)acetamide
CAS 359447-60-2C14H13N3O3S