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Murcko scaffold

Ring system with 4 rings and 23 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
10
With full pages
1
Scaffold SMILES

O=c1c(=Cc2cccnc2)sc2n1CN(c1ccccc1)CN=2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(=Cc2cccnc2)sc2n1CN(c1ccccc1)CN=2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

(7Z)-3-(4-Bromophenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C17H13BrN4OS, CAS 690687-05-9
(7Z)-3-(4-Bromophenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 690687-05-9C17H13BrN4OS
(7Z)-3-Phenyl-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C17H14N4OS, CAS 378222-87-8
(7Z)-3-Phenyl-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 378222-87-8C17H14N4OS
(7Z)-3-(4-Acetylphenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C19H16N4O2S, CAS 352329-77-2
(7Z)-3-(4-Acetylphenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 352329-77-2C19H16N4O2S
(7Z)-3-(3-Fluorophenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C17H13FN4OS, CAS 381709-55-3
(7Z)-3-(3-Fluorophenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 381709-55-3C17H13FN4OS
(7Z)-3-(3-Nitrophenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C17H13N5O3S, CAS 381183-99-9
(7Z)-3-(3-Nitrophenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 381183-99-9C17H13N5O3S
(7Z)-3-(4-Methoxyphenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C18H16N4O2S, CAS 352329-74-9
(7Z)-3-(4-Methoxyphenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 352329-74-9C18H16N4O2S
(7Z)-3-(3,4-Dimethylphenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C19H18N4OS, CAS 690693-53-9
(7Z)-3-(3,4-Dimethylphenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 690693-53-9C19H18N4OS
Ethyl 4-[(7Z)-6-oxo-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-3-yl]benzoate chemical structure, C20H18N4O3S, CAS 380595-65-3
Ethyl 4-[(7Z)-6-oxo-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-3-yl]benzoate
CAS 380595-65-3C20H18N4O3S
(7Z)-3-(3-Bromophenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C17H13BrN4OS, CAS 498569-96-3
(7Z)-3-(3-Bromophenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 498569-96-3C17H13BrN4OS
(7Z)-3-(4-Nitrophenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one chemical structure, C17H13N5O3S, CAS 378222-71-0
(7Z)-3-(4-Nitrophenyl)-7-(pyridin-3-ylmethylidene)-2,4-dihydro-[1,3]thiazolo[3,2-a][1,3,5]triazin-6-one
CAS 378222-71-0C17H13N5O3S