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Murcko scaffold

Ring system with 4 rings and 23 atoms

26 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
26
With full pages
9
Scaffold SMILES

O=C(c1ccccc1)c1cc2ccc(-c3ccccc3)nc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1cc2ccc(-c3ccccc3)nc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

(3-Amino-6-phenylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone chemical structure, C20H14N2OS, CAS 115809-16-0
(3-Amino-6-phenylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone
CAS 115809-16-0C20H14N2OS
[3-Amino-6-(3,4-dimethoxyphenyl)thieno[2,3-b]pyridin-2-yl](phenyl)methanone chemical structure, C22H18N2O3S, CAS 500277-16-7
[3-Amino-6-(3,4-dimethoxyphenyl)thieno[2,3-b]pyridin-2-yl](phenyl)methanone
CAS 500277-16-7C22H18N2O3S
[3-Amino-6-(3-methoxyphenyl)thieno[2,3-b]pyridin-2-yl]-(4-bromophenyl)methanone chemical structure, C21H15BrN2O2S, CAS 445268-02-0
[3-Amino-6-(3-methoxyphenyl)thieno[2,3-b]pyridin-2-yl]-(4-bromophenyl)methanone
CAS 445268-02-0C21H15BrN2O2S
[3-Amino-6-(4-methoxyphenyl)thieno[2,3-b]pyridin-2-yl]-(4-bromophenyl)methanone chemical structure, C21H15BrN2O2S, CAS 445268-78-0
[3-Amino-6-(4-methoxyphenyl)thieno[2,3-b]pyridin-2-yl]-(4-bromophenyl)methanone
CAS 445268-78-0C21H15BrN2O2S
[3-Amino-6-(4-methoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-(3,4-dimethoxyphenyl)methanone chemical structure, C24H19F3N2O4S, CAS 488811-69-4
[3-Amino-6-(4-methoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-(3,4-dimethoxyphenyl)methanone
CAS 488811-69-4C24H19F3N2O4S
[3-Amino-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl](4-methoxyphenyl)methanone chemical structure, C24H19F3N2O4S, CAS 625369-52-0
[3-Amino-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl](4-methoxyphenyl)methanone
CAS 625369-52-0C24H19F3N2O4S
[3-Amino-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl](3,4-dimethoxyphenyl)methanone chemical structure, C25H21F3N2O5S, CAS 489400-81-9
[3-Amino-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl](3,4-dimethoxyphenyl)methanone
CAS 489400-81-9C25H21F3N2O5S
[3-Amino-6-phenyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-(3,4-dimethoxyphenyl)methanone chemical structure, C23H17F3N2O3S, CAS 445385-18-2
[3-Amino-6-phenyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-(3,4-dimethoxyphenyl)methanone
CAS 445385-18-2C23H17F3N2O3S
(3-Amino-6-phenylthieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone chemical structure, C20H13ClN2OS, CAS 5271-85-2
(3-Amino-6-phenylthieno[2,3-b]pyridin-2-yl)(4-chlorophenyl)methanone
CAS 5271-85-2C20H13ClN2OS
[3-Amino-6-(4-methoxyphenyl)thieno[2,3-b]pyridin-2-yl](4-methoxyphenyl)methanone chemical structure, C22H18N2O3S, CAS 327070-63-3
[3-Amino-6-(4-methoxyphenyl)thieno[2,3-b]pyridin-2-yl](4-methoxyphenyl)methanone
CAS 327070-63-3C22H18N2O3S
[3-Amino-6-(2,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl](phenyl)methanone chemical structure, C23H17F3N2O3S, CAS 625377-58-4
[3-Amino-6-(2,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl](phenyl)methanone
CAS 625377-58-4C23H17F3N2O3S
(3-Amino-6-phenylthieno[2,3-b]pyridin-2-yl)(4-methoxyphenyl)methanone chemical structure, C21H16N2O2S, CAS 316362-41-1
(3-Amino-6-phenylthieno[2,3-b]pyridin-2-yl)(4-methoxyphenyl)methanone
CAS 316362-41-1C21H16N2O2S
[3-Amino-6-phenyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-(4-methoxyphenyl)methanone chemical structure, C22H15F3N2O2S, CAS 313380-11-9
[3-Amino-6-phenyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-(4-methoxyphenyl)methanone
CAS 313380-11-9C22H15F3N2O2S
[3-Amino-6-phenyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-phenylmethanone chemical structure, C21H13F3N2OS, CAS 299164-11-7
[3-Amino-6-phenyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-phenylmethanone
CAS 299164-11-7C21H13F3N2OS
(3-Amino-6-(4-methylphenyl)-4-(trifluoromethyl)thieno(2,3-B)pyridin-2-yl)(phenyl)methanone chemical structure, C22H15F3N2OS, CAS 618074-38-7
(3-Amino-6-(4-methylphenyl)-4-(trifluoromethyl)thieno(2,3-B)pyridin-2-yl)(phenyl)methanone
CAS 618074-38-7C22H15F3N2OS
[3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno[2,3-B]pyridin-2-yl](4-methylphenyl)methanone chemical structure, C22H14BrF3N2OS, CAS 618383-55-4
[3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno[2,3-B]pyridin-2-yl](4-methylphenyl)methanone
CAS 618383-55-4C22H14BrF3N2OS
(3-Amino-6-(4-methylphenyl)-4-(trifluoromethyl)thieno(2,3-B)pyridin-2-yl)(4-methylphenyl)methanone chemical structure, C23H17F3N2OS, CAS 618074-72-9
(3-Amino-6-(4-methylphenyl)-4-(trifluoromethyl)thieno(2,3-B)pyridin-2-yl)(4-methylphenyl)methanone
CAS 618074-72-9C23H17F3N2OS
(3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno(2,3-B)pyridin-2-yl)(4-methoxyphenyl)methanone chemical structure, C22H14BrF3N2O2S, CAS 618383-57-6
(3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno(2,3-B)pyridin-2-yl)(4-methoxyphenyl)methanone
CAS 618383-57-6C22H14BrF3N2O2S
[3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno[2,3-B]pyridin-2-yl](4-fluorophenyl)methanone chemical structure, C21H11BrF4N2OS, CAS 618383-53-2
[3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno[2,3-B]pyridin-2-yl](4-fluorophenyl)methanone
CAS 618383-53-2C21H11BrF4N2OS
[3-Amino-6-phenyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl](4-ethylphenyl)methanone chemical structure, C23H17F3N2OS, CAS 329205-73-4
[3-Amino-6-phenyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl](4-ethylphenyl)methanone
CAS 329205-73-4C23H17F3N2OS
(3-Amino-6-(4-methylphenyl)-4-(trifluoromethyl)thieno(2,3-B)pyridin-2-yl)(3-bromo-4-methoxyphenyl)methanone chemical structure, C23H16BrF3N2O2S, CAS 618074-82-1
(3-Amino-6-(4-methylphenyl)-4-(trifluoromethyl)thieno(2,3-B)pyridin-2-yl)(3-bromo-4-methoxyphenyl)methanone
CAS 618074-82-1C23H16BrF3N2O2S
(3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno(2,3-b)pyridin-2-yl)(3-fluoro-4-methoxyphenyl)methanone chemical structure, C22H13BrF4N2O2S, CAS 618383-52-1
(3-Amino-6-(4-bromophenyl)-4-(trifluoromethyl)thieno(2,3-b)pyridin-2-yl)(3-fluoro-4-methoxyphenyl)methanone
CAS 618383-52-1C22H13BrF4N2O2S
(3-Amino-5-ethyl-4-methyl-6-phenylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone chemical structure, C23H20N2OS, CAS 151693-84-4
(3-Amino-5-ethyl-4-methyl-6-phenylthieno[2,3-b]pyridin-2-yl)(phenyl)methanone
CAS 151693-84-4C23H20N2OS
4-[3-Amino-6-(4-methoxyphenyl)thieno[2,3-B]pyridine-2-carbonyl]benzene-1,2-diol chemical structure, C21H16N2O4S, CAS 934090-82-1
4-[3-Amino-6-(4-methoxyphenyl)thieno[2,3-B]pyridine-2-carbonyl]benzene-1,2-diol
CAS 934090-82-1C21H16N2O4S