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Murcko scaffold

Ring system with 4 rings and 24 atoms

24 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 24
Chemicals: 24
With full pages: 17

Scaffold SMILES

O=c1nc2sc(=Cc3ccccc3)c(=O)n2nc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1nc2sc(=Cc3ccccc3)c(=O)n2nc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-(4-Isopropylbenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C21H17N3O2S, CAS 463366-98-5

2-(4-Isopropylbenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 463366-98-5C₂₁H₁₇N₃O₂S

2-Bromo-4-((Z)-(3,7-dioxo-6-phenyl-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazin-2(3H)-ylidene)methyl)-6-methoxyphenyl acetate chemical structure, C21H14BrN3O5S, CAS 463959-60-6

2-Bromo-4-((Z)-(3,7-dioxo-6-phenyl-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazin-2(3H)-ylidene)methyl)-6-methoxyphenyl acetate

CAS 463959-60-6C₂₁H₁₄BrN₃O₅S

(2E)-2-(2,5-Dimethoxybenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione chemical structure, C20H15N3O4S, CAS 307506-42-9

(2E)-2-(2,5-Dimethoxybenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione

CAS 307506-42-9C₂₀H₁₅N₃O₄S

(2Z)-2-(4-Ethoxy-3-methoxybenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione chemical structure, C21H17N3O4S, CAS 463366-95-2

(2Z)-2-(4-Ethoxy-3-methoxybenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione

CAS 463366-95-2C₂₁H₁₇N₃O₄S

(2Z)-2-(5-Bromo-2-methoxybenzylidene)-6-phenyl-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione chemical structure, C19H12BrN3O3S, CAS 606955-75-3

(2Z)-2-(5-Bromo-2-methoxybenzylidene)-6-phenyl-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione

CAS 606955-75-3C₁₉H₁₂BrN₃O₃S

(2Z)-2-(4-Isobutoxy-3-methoxybenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione chemical structure, C23H21N3O4S, CAS 606956-86-9

(2Z)-2-(4-Isobutoxy-3-methoxybenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione

CAS 606956-86-9C₂₃H₂₁N₃O₄S

4-[(Z)-(3,7-Dioxo-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazin-2(3H)-ylidene)methyl]-2,6-dimethylphenyl acetate chemical structure, C22H17N3O4S, CAS 606956-59-6

4-[(Z)-(3,7-Dioxo-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazin-2(3H)-ylidene)methyl]-2,6-dimethylphenyl acetate

CAS 606956-59-6C₂₂H₁₇N₃O₄S

(2E)-6-Phenyl-2-(3,4,5-trimethoxybenzylidene)-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione chemical structure, C21H17N3O5S, CAS 463366-91-8

(2E)-6-Phenyl-2-(3,4,5-trimethoxybenzylidene)-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione

CAS 463366-91-8C₂₁H₁₇N₃O₅S

(2Z)-2-[(4-Butoxy-3-methoxyphenyl)methylidene]-6-phenyl-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7-dione chemical structure, C23H21N3O4S, CAS 378762-85-7

(2Z)-2-[(4-Butoxy-3-methoxyphenyl)methylidene]-6-phenyl-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7-dione

CAS 378762-85-7C₂₃H₂₁N₃O₄S

(2Z)-2-[3-Methoxy-4-(octyloxy)benzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C27H29N3O4S, CAS 797799-48-5

(2Z)-2-[3-Methoxy-4-(octyloxy)benzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 797799-48-5C₂₇H₂₉N₃O₄S

(2Z)-6-Phenyl-2-(2-propoxybenzylidene)-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione chemical structure, C21H17N3O3S, CAS 609794-93-6

(2Z)-6-Phenyl-2-(2-propoxybenzylidene)-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione

CAS 609794-93-6C₂₁H₁₇N₃O₃S

(2Z)-2-[2-(Hexyloxy)benzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C24H23N3O3S, CAS 797016-29-6

(2Z)-2-[2-(Hexyloxy)benzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 797016-29-6C₂₄H₂₃N₃O₃S

(2Z)-2-(3-Ethoxy-4-propoxybenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione chemical structure, C23H21N3O4S, CAS 617694-37-8

(2Z)-2-(3-Ethoxy-4-propoxybenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione

CAS 617694-37-8C₂₃H₂₁N₃O₄S

(2E)-2-[2-(Pentyloxy)benzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione chemical structure, C23H21N3O3S, CAS 617695-14-4

(2E)-2-[2-(Pentyloxy)benzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione

CAS 617695-14-4C₂₃H₂₁N₃O₃S

(2Z)-2-[3-Ethoxy-4-(pentyloxy)benzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C25H25N3O4S, CAS 797772-67-9

(2Z)-2-[3-Ethoxy-4-(pentyloxy)benzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 797772-67-9C₂₅H₂₅N₃O₄S

(2Z)-2-[4-(Heptyloxy)-3-methoxybenzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C26H27N3O4S, CAS 797773-32-1

(2Z)-2-[4-(Heptyloxy)-3-methoxybenzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 797773-32-1C₂₆H₂₇N₃O₄S

4-[(E)-(3,7-Dioxo-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazin-2(3H)-ylidene)methyl]phenyl acetate chemical structure, C20H13N3O4S, CAS 463959-53-7

4-[(E)-(3,7-Dioxo-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazin-2(3H)-ylidene)methyl]phenyl acetate

CAS 463959-53-7C₂₀H₁₃N₃O₄S

(2E)-2-[4-(Methylsulfanyl)benzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione chemical structure, C19H13N3O2S2, CAS 606956-72-3

(2E)-2-[4-(Methylsulfanyl)benzylidene]-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione

CAS 606956-72-3C₁₉H₁₃N₃O₂S₂

6-Phenyl-2-{[4-(prop-2-en-1-yloxy)phenyl]methylidene}-2H,3H,7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7-dione chemical structure, C21H15N3O3S, CAS 518351-48-9

6-Phenyl-2-{[4-(prop-2-en-1-yloxy)phenyl]methylidene}-2H,3H,7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7-dione

CAS 518351-48-9C₂₁H₁₅N₃O₃S

2-(2-Bromobenzylidene)-6-PH-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione chemical structure, C18H10BrN3O2S, CAS 463366-89-4

2-(2-Bromobenzylidene)-6-PH-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione

CAS 463366-89-4C₁₈H₁₀BrN₃O₂S

(2E)-2-(2-(Allyloxy)benzylidene)-6-phenyl-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione chemical structure, C21H15N3O3S, CAS 606956-44-9

(2E)-2-(2-(Allyloxy)benzylidene)-6-phenyl-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione

CAS 606956-44-9C₂₁H₁₅N₃O₃S

(2Z)-2-(3-Fluorobenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione chemical structure, C18H10FN3O2S, CAS 606956-01-8

(2Z)-2-(3-Fluorobenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione

CAS 606956-01-8C₁₈H₁₀FN₃O₂S

(2E)-2-(2,3-Dimethoxybenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione chemical structure, C20H15N3O4S, CAS 463366-94-1

(2E)-2-(2,3-Dimethoxybenzylidene)-6-phenyl-7H-[1,3]thiazolo[3,2-B][1,2,4]triazine-3,7(2H)-dione

CAS 463366-94-1C₂₀H₁₅N₃O₄S

2-(4-Ethylbenzylidene)-6-PH-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione chemical structure, C20H15N3O2S, CAS 606955-91-3

2-(4-Ethylbenzylidene)-6-PH-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione

CAS 606955-91-3C₂₀H₁₅N₃O₂S