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Murcko scaffold

Ring system with 2 rings and 17 atoms

152 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
152
With full pages
4
Scaffold SMILES

O=S(=O)(NCCc1cccs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(NCCc1cccs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 152 chemicals

Linotroban chemical structure, C14H15NO5S2, CAS 120824-08-0
Linotroban
CAS 120824-08-0C14H15NO5S2
HN 11501 chemical structure, C14H14ClNO5S2, CAS 120824-10-4
HN 11501
CAS 120824-10-4C14H14ClNO5S2
4-Methyl-N-[2-(thiophen-2-yl)ethyl]benzene-1-sulfonamide chemical structure, C13H15NO2S2, CAS 102996-95-2
4-Methyl-N-[2-(thiophen-2-yl)ethyl]benzene-1-sulfonamide
CAS 102996-95-2C13H15NO2S2
2-{N-[2-(Thiophen-2-yl)ethyl]4-methylbenzenesulfonamido}acetic acid chemical structure, C15H17NO4S2, CAS 102996-97-4
2-{N-[2-(Thiophen-2-yl)ethyl]4-methylbenzenesulfonamido}acetic acid
CAS 102996-97-4C15H17NO4S2
N-(2-Thiophen-2-ylethyl)-3-(trifluoromethyl)benzenesulfonamide chemical structure, C13H12F3NO2S2, CAS 1023212-35-2
N-(2-Thiophen-2-ylethyl)-3-(trifluoromethyl)benzenesulfonamide
CAS 1023212-35-2C13H12F3NO2S2
4-Bromo-N-(2-thiophen-2-ylethyl)benzenesulfonamide chemical structure, C12H12BrNO2S2, CAS 321711-63-1
4-Bromo-N-(2-thiophen-2-ylethyl)benzenesulfonamide
CAS 321711-63-1C12H12BrNO2S2
Ethyl 2-{N-[2-(thiophen-2-yl)ethyl]4-methylbenzenesulfonamido}acetate chemical structure, C17H21NO4S2, CAS 102996-96-3
Ethyl 2-{N-[2-(thiophen-2-yl)ethyl]4-methylbenzenesulfonamido}acetate
CAS 102996-96-3C17H21NO4S2
N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-4-methylbenzenesulfonamide chemical structure, C15H20N2O2S2, CAS 941977-59-9
N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-4-methylbenzenesulfonamide
CAS 941977-59-9C15H20N2O2S2
N-[2-(Dimethylamino)-2-(thiophen-2-yl)ethyl]-4-fluorobenzene-1-sulfonamide chemical structure, C14H17FN2O2S2, CAS 941934-21-0
N-[2-(Dimethylamino)-2-(thiophen-2-yl)ethyl]-4-fluorobenzene-1-sulfonamide
CAS 941934-21-0C14H17FN2O2S2
N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-4-ethoxybenzenesulfonamide chemical structure, C16H22N2O3S2, CAS 941872-41-9
N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-4-ethoxybenzenesulfonamide
CAS 941872-41-9C16H22N2O3S2
N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-4-methoxy-3-methylbenzenesulfonamide chemical structure, C16H22N2O3S2, CAS 941977-61-3
N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-4-methoxy-3-methylbenzenesulfonamide
CAS 941977-61-3C16H22N2O3S2
N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-3-nitrobenzenesulfonamide chemical structure, C14H17N3O4S2, CAS 941934-24-3
N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-3-nitrobenzenesulfonamide
CAS 941934-24-3C14H17N3O4S2
N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-2,5-dimethoxybenzenesulfonamide chemical structure, C16H22N2O4S2, CAS 941934-27-6
N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-2,5-dimethoxybenzenesulfonamide
CAS 941934-27-6C16H22N2O4S2
3-{[2-(Thiophen-2-yl)ethyl]sulfamoyl}benzoic acid chemical structure, C13H13NO4S2, CAS 893761-27-8
3-{[2-(Thiophen-2-yl)ethyl]sulfamoyl}benzoic acid
CAS 893761-27-8C13H13NO4S2
4-{[2-(Thiophen-2-yl)ethyl]sulfamoyl}benzoic acid chemical structure, C13H13NO4S2, CAS 1031130-62-7
4-{[2-(Thiophen-2-yl)ethyl]sulfamoyl}benzoic acid
CAS 1031130-62-7C13H13NO4S2
N-(1-(5-Formylthiophen-2-yl)propan-2-yl)-4-methylbenzenesulfonamide chemical structure, C15H17NO3S2, CAS 1170097-60-5
N-(1-(5-Formylthiophen-2-yl)propan-2-yl)-4-methylbenzenesulfonamide
CAS 1170097-60-5C15H17NO3S2
3-Chloro-4-methoxy-N-(1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide chemical structure, C14H16ClNO3S2, CAS 1206989-58-3
3-Chloro-4-methoxy-N-(1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide
CAS 1206989-58-3C14H16ClNO3S2
4-Ethoxy-3,5-dimethyl-N-(1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide chemical structure, C17H23NO3S2, CAS 1208519-60-1
4-Ethoxy-3,5-dimethyl-N-(1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide
CAS 1208519-60-1C17H23NO3S2
2,5-Dichloro-N-(2-(dimethylamino)-2-(thiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C14H16Cl2N2O2S2, CAS 1211019-34-9
2,5-Dichloro-N-(2-(dimethylamino)-2-(thiophen-2-yl)ethyl)benzenesulfonamide
CAS 1211019-34-9C14H16Cl2N2O2S2
N-(4-(N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)sulfamoyl)phenyl)isobutyramide chemical structure, C18H25N3O3S2, CAS 1210836-69-3
N-(4-(N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)sulfamoyl)phenyl)isobutyramide
CAS 1210836-69-3C18H25N3O3S2
N-[2-Hydroxy-2-(3-methylthiophen-2-yl)ethyl]benzenesulfonamide chemical structure, C13H15NO3S2, CAS 1351608-05-3
N-[2-Hydroxy-2-(3-methylthiophen-2-yl)ethyl]benzenesulfonamide
CAS 1351608-05-3C13H15NO3S2
4-Fluoro-N-(2-hydroxy-2-(3-methylthiophen-2-yl)ethyl)-3-methylbenzenesulfonamide chemical structure, C14H16FNO3S2, CAS 1351604-75-5
4-Fluoro-N-(2-hydroxy-2-(3-methylthiophen-2-yl)ethyl)-3-methylbenzenesulfonamide
CAS 1351604-75-5C14H16FNO3S2
2,6-Difluoro-N-(2-hydroxy-2-(3-methylthiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C13H13F2NO3S2, CAS 1351613-32-5
2,6-Difluoro-N-(2-hydroxy-2-(3-methylthiophen-2-yl)ethyl)benzenesulfonamide
CAS 1351613-32-5C13H13F2NO3S2
N-(2-Hydroxy-2-(3-methylthiophen-2-yl)ethyl)-2,4,5-trimethylbenzenesulfonamide chemical structure, C16H21NO3S2, CAS 1351631-11-2
N-(2-Hydroxy-2-(3-methylthiophen-2-yl)ethyl)-2,4,5-trimethylbenzenesulfonamide
CAS 1351631-11-2C16H21NO3S2