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Murcko scaffold

Ring system with 4 rings and 25 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
9
With full pages
2
Scaffold SMILES

O=c1c(Cc2c[nH]n(-c3ccccc3)c2=O)c[nH]n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(Cc2c[nH]n(-c3ccccc3)c2=O)c[nH]n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

3H-Pyrazol-3-one, 4,4'-butylidenebis[1,2-dihydro-1,5-dimethyl-2-phenyl- chemical structure, C26H30N4O2, CAS 1461-17-2
3H-Pyrazol-3-one, 4,4'-butylidenebis[1,2-dihydro-1,5-dimethyl-2-phenyl-
CAS 1461-17-2C26H30N4O2
Diantipyrylmethane chemical structure, C23H24N4O2, CAS 1251-85-0
Diantipyrylmethane
CAS 1251-85-0C23H24N4O2
4-[1-(1,5-Dimethyl-3-oxo-2-phenylpyrazol-4-yl)ethyl]-1,5-dimethyl-2-phenylpyrazol-3-one chemical structure, C24H26N4O2, CAS 1606-56-0
4-[1-(1,5-Dimethyl-3-oxo-2-phenylpyrazol-4-yl)ethyl]-1,5-dimethyl-2-phenylpyrazol-3-one
CAS 1606-56-0C24H26N4O2
1H-Pyrazol-5-ol, 4,4'-(2-methylpropylidene)bis[3-methyl-1-phenyl- chemical structure, C24H26N4O2, CAS 89243-25-4
1H-Pyrazol-5-ol, 4,4'-(2-methylpropylidene)bis[3-methyl-1-phenyl-
CAS 89243-25-4C24H26N4O2
4,4'-Diantipyrylmethane 1-hydrate chemical structure, C23H26N4O3, CAS 71501-10-5
4,4'-Diantipyrylmethane 1-hydrate
CAS 71501-10-5C23H26N4O3
4,4'-(Pentane-1,1-diyl)bis(5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one) chemical structure, C25H28N4O2, CAS 89243-26-5
4,4'-(Pentane-1,1-diyl)bis(5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one)
CAS 89243-26-5C25H28N4O2
4,4'-(Hexane-1,1-diyl)bis(5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one) chemical structure, C26H30N4O2, CAS 89243-27-6
4,4'-(Hexane-1,1-diyl)bis(5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one)
CAS 89243-27-6C26H30N4O2
4,4'-(Heptane-1,1-diyl)bis(5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one) chemical structure, C27H32N4O2, CAS 89243-28-7
4,4'-(Heptane-1,1-diyl)bis(5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one)
CAS 89243-28-7C27H32N4O2
4,4'-(Decane-1,1-diyl)bis(5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one) chemical structure, C30H38N4O2, CAS 89243-29-8
4,4'-(Decane-1,1-diyl)bis(5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one)
CAS 89243-29-8C30H38N4O2