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Murcko scaffold

1-Phenyl-2-{[5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}ethan-1-one scaffold

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
10
With full pages
3
Scaffold SMILES

O=C(CSc1nnc(-c2cccnc2)o1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenyl-2-{[5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}ethan-1-one page
Murcko scaffold O=C(CSc1nnc(-c2cccnc2)o1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1-(4-Nitrophenyl)-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone chemical structure, C15H10N4O4S, CAS 327978-83-6
1-(4-Nitrophenyl)-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone
CAS 327978-83-6C15H10N4O4S
1-(4-Chlorophenyl)-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone chemical structure, C15H10ClN3O2S, CAS 337488-89-8
1-(4-Chlorophenyl)-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone
CAS 337488-89-8C15H10ClN3O2S
1-(4-Bromophenyl)-2-((5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C15H10BrN3O2S, CAS 327978-84-7
1-(4-Bromophenyl)-2-((5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 327978-84-7C15H10BrN3O2S
1-Phenyl-2-{[5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}ethan-1-one chemical structure, C15H11N3O2S, CAS 81555-95-5
1-Phenyl-2-{[5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}ethan-1-one
CAS 81555-95-5C15H11N3O2S
1-(4-Chlorophenyl)-2-[[5-[2-methyl-6-(trifluoromethyl)-3-pyridinyl]-1,3,4-oxadiazol-2-yl]thio]ethanone chemical structure, C17H11ClF3N3O2S, CAS 402479-95-2
1-(4-Chlorophenyl)-2-[[5-[2-methyl-6-(trifluoromethyl)-3-pyridinyl]-1,3,4-oxadiazol-2-yl]thio]ethanone
CAS 402479-95-2C17H11ClF3N3O2S
1-Phenyl-2-{[5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}propan-1-one chemical structure, C16H13N3O2S, CAS 302552-46-1
1-Phenyl-2-{[5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}propan-1-one
CAS 302552-46-1C16H13N3O2S
1-(3-Nitrophenyl)-2-((5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C15H10N4O4S, CAS 441289-30-1
1-(3-Nitrophenyl)-2-((5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 441289-30-1C15H10N4O4S
1-(4-Ethylphenyl)-2-((5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C17H15N3O2S, CAS 538336-73-1
1-(4-Ethylphenyl)-2-((5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 538336-73-1C17H15N3O2S
1-(4-Ethoxyphenyl)-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone chemical structure, C17H15N3O3S, CAS 538336-88-8
1-(4-Ethoxyphenyl)-2-[(5-pyridin-3-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone
CAS 538336-88-8C17H15N3O3S
1-(4-(Difluoromethoxy)phenyl)-2-((5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C16H11F2N3O3S, CAS 538336-91-3
1-(4-(Difluoromethoxy)phenyl)-2-((5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 538336-91-3C16H11F2N3O3S