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Murcko scaffold

4-Thiazolidinone, 3-phenyl-5-(phenylmethylene)-2-thioxo-, (5Z)- scaffold

506 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 20
Chemicals: 506
With full pages: 13

Scaffold SMILES

O=C1C(=Cc2ccccc2)SC(=S)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 4-Thiazolidinone, 3-phenyl-5-(phenylmethylene)-2-thioxo-, (5Z)- page

Murcko scaffold O=C1C(=Cc2ccccc2)SC(=S)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 506 chemicals

4-Thiazolidinone, 3-phenyl-5-(phenylmethylene)-2-thioxo-, (5Z)- chemical structure, C16H11NOS2, CAS 253447-22-2

4-Thiazolidinone, 3-phenyl-5-(phenylmethylene)-2-thioxo-, (5Z)-

CAS 253447-22-2C₁₆H₁₁NOS₂

2-[4-[(4-Oxo-3-phenyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid chemical structure, C18H13NO4S2, CAS 88590-46-9

2-[4-[(4-Oxo-3-phenyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid

CAS 88590-46-9C₁₈H₁₃NO₄S₂

{2-[(4-Oxo-3-phenyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy}acetic acid chemical structure, C18H13NO4S2, CAS 88590-45-8

{2-[(4-Oxo-3-phenyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy}acetic acid

CAS 88590-45-8C₁₈H₁₃NO₄S₂

Ethyl 2-cyano-3-{4-[(4-oxo-3-phenyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenyl}prop-2-enoate chemical structure, C22H16N2O3S2, CAS 29947-21-5

Ethyl 2-cyano-3-{4-[(4-oxo-3-phenyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenyl}prop-2-enoate

CAS 29947-21-5C₂₂H₁₆N₂O₃S₂

CFTR(inh)-172 chemical structure, C18H10F3NO3S2, CAS 307510-92-5

CAS 307510-92-5C₁₈H₁₀F₃NO₃S₂

4-(5-Phenylmethylene-4-oxo-2-thionothiazolidin-3-yl)benzoic acid chemical structure, C17H11NO3S2

4-(5-Phenylmethylene-4-oxo-2-thionothiazolidin-3-yl)benzoic acid

C₁₇H₁₁NO₃S₂

4-[5-(4-Fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]benzoic acid chemical structure, C17H10FNO3S2, CAS 862827-73-4

4-[5-(4-Fluorobenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]benzoic acid

CAS 862827-73-4C₁₇H₁₀FNO₃S₂

(Z)-4-(5-(4-Bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)benzoic acid chemical structure, C17H10BrNO3S2, CAS 1100514-55-3

(Z)-4-(5-(4-Bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)benzoic acid

CAS 1100514-55-3C₁₇H₁₀BrNO₃S₂

3-{(5Z)-5-[4-(Dimethylamino)benzylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}benzoic acid chemical structure, C19H16N2O3S2, CAS 303026-34-8

3-{(5Z)-5-[4-(Dimethylamino)benzylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}benzoic acid

CAS 303026-34-8C₁₉H₁₆N₂O₃S₂

3-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-thiazolidin-3-yl}-benzoic acid chemical structure, C17H11NO3S2, CAS 862827-52-9

3-{4-Oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-thiazolidin-3-yl}-benzoic acid

CAS 862827-52-9C₁₇H₁₁NO₃S₂

4-[(5Z)-5-(4-Ethoxy-3-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]benzoic acid chemical structure, C20H17NO5S2, CAS 329227-67-0

4-[(5Z)-5-(4-Ethoxy-3-methoxybenzylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]benzoic acid

CAS 329227-67-0C₂₀H₁₇NO₅S₂

3-[(5E)-5-[(2-Fluorophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid chemical structure, C17H10FNO3S2, CAS 461684-21-9

3-[(5E)-5-[(2-Fluorophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid

CAS 461684-21-9C₁₇H₁₀FNO₃S₂

(E)-5-(3,4-Dimethoxybenzylidene)-3-(3-fluorophenyl)-2-thioxothiazolidin-4-one chemical structure, C18H14FNO3S2, CAS 300827-60-5

(E)-5-(3,4-Dimethoxybenzylidene)-3-(3-fluorophenyl)-2-thioxothiazolidin-4-one

CAS 300827-60-5C₁₈H₁₄FNO₃S₂

5-(2,4-Dimethoxybenzylidene)-3-(3-fluorophenyl)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C18H14FNO3S2, CAS 327053-97-4

5-(2,4-Dimethoxybenzylidene)-3-(3-fluorophenyl)-2-thioxo-1,3-thiazolidin-4-one

CAS 327053-97-4C₁₈H₁₄FNO₃S₂

(Z)-3-(3-Fluorophenyl)-5-(2-methoxybenzylidene)-2-thioxothiazolidin-4-one chemical structure, C17H12FNO2S2, CAS 292173-32-1

(Z)-3-(3-Fluorophenyl)-5-(2-methoxybenzylidene)-2-thioxothiazolidin-4-one

CAS 292173-32-1C₁₇H₁₂FNO₂S₂

(E)-5-(3-Fluorobenzylidene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-one chemical structure, C17H9F4NOS2, CAS 314047-56-8

(E)-5-(3-Fluorobenzylidene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-one

CAS 314047-56-8C₁₇H₉F₄NOS₂

(5E)-3-(4-Fluorophenyl)-5-[(3-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C16H9FN2O3S2, CAS 300827-47-8

(5E)-3-(4-Fluorophenyl)-5-[(3-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

CAS 300827-47-8C₁₆H₉FN₂O₃S₂

(5Z)-5-(3,4-Dimethoxybenzylidene)-3-(4-fluorophenyl)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C18H14FNO3S2, CAS 5548-07-2

(5Z)-5-(3,4-Dimethoxybenzylidene)-3-(4-fluorophenyl)-2-thioxo-1,3-thiazolidin-4-one

CAS 5548-07-2C₁₈H₁₄FNO₃S₂

(5Z)-5-(3-Ethoxy-4-hydroxybenzylidene)-3-(3-methoxyphenyl)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C19H17NO4S2, CAS 306323-75-1

(5Z)-5-(3-Ethoxy-4-hydroxybenzylidene)-3-(3-methoxyphenyl)-2-thioxo-1,3-thiazolidin-4-one

CAS 306323-75-1C₁₉H₁₇NO₄S₂

(Z)-5-(4-Hydroxy-3-methoxybenzylidene)-3-(3-hydroxyphenyl)-2-thioxothiazolidin-4-one chemical structure, C17H13NO4S2, CAS 258347-54-5

(Z)-5-(4-Hydroxy-3-methoxybenzylidene)-3-(3-hydroxyphenyl)-2-thioxothiazolidin-4-one

CAS 258347-54-5C₁₇H₁₃NO₄S₂

(5Z)-3-(3-Hydroxyphenyl)-5-(4-methylbenzylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C17H13NO2S2, CAS 300830-17-5

(5Z)-3-(3-Hydroxyphenyl)-5-(4-methylbenzylidene)-2-thioxo-1,3-thiazolidin-4-one

CAS 300830-17-5C₁₇H₁₃NO₂S₂

(Z)-4-((3-(4-Hydroxyphenyl)-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzoic acid chemical structure, C17H11NO4S2, CAS 325834-03-5

(Z)-4-((3-(4-Hydroxyphenyl)-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzoic acid

CAS 325834-03-5C₁₇H₁₁NO₄S₂

(Z)-5-(4-Hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-2-thioxothiazolidin-4-one chemical structure, C17H13NO4S2, CAS 120841-44-3

(Z)-5-(4-Hydroxy-3-methoxybenzylidene)-3-(4-hydroxyphenyl)-2-thioxothiazolidin-4-one

CAS 120841-44-3C₁₇H₁₃NO₄S₂

(5Z)-3-(4-Chlorophenyl)-5-(3,4-dimethoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C18H14ClNO3S2, CAS 383893-92-3

(5Z)-3-(4-Chlorophenyl)-5-(3,4-dimethoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one

CAS 383893-92-3C₁₈H₁₄ClNO₃S₂