Murcko scaffold
2-Naphthalenecarboxamide, 5,6,7,8-tetrahydro-N-phenyl- scaffold
11 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 19
- Chemicals
- 11
- With full pages
- 5
Scaffold SMILES
O=C(Nc1ccccc1)c1ccc2c(c1)CCCC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 11 of 11 chemicals
Ro 40-6055
CAS 102121-60-8C22H25NO3
4-(Methyloctadecylamino)-3-((5,6,7,8-tetrahydro-1-hydroxy-2-naphthyl)carbamoyl)benzenesulphonic acid
CAS 2589-61-9C36H56N2O5S
Ethyl 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoate
CAS 127697-58-9C24H29NO3
N-(3-Methoxyphenyl)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
CAS 681168-98-9C18H19NO2
N-(3,5-Dichlorophenyl)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
CAS 681168-85-4C17H15Cl2NO
N-(4-Sulfamoylphenyl)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
CAS 681169-23-3C17H18N2O3S
N-(3-Acetylphenyl)-5,6,7,8-tetrahydronaphthalene-2-carboxamide
CAS 681169-83-5C19H19NO2
2-Naphthalenecarboxamide, 5,6,7,8-tetrahydro-N-phenyl-
CAS 681168-79-6C17H17NO
2,6-Difluoro-4-[(3-hydroxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalene-2-carbonyl)-amino]-benzoic acid
CAS 321995-62-4C22H23F2NO4
Irx-5183
CAS 367273-07-2C22H22ClF2NO4
2,6-Difluoro-4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoic acid
CAS 191469-29-1C22H23F2NO3