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Murcko scaffold

5-Phenyl-2H-1,3-benzodioxole scaffold

146 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
146
With full pages
5
Scaffold SMILES

c1ccc(-c2ccc3c(c2)OCO3)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Phenyl-2H-1,3-benzodioxole page
Murcko scaffold c1ccc(-c2ccc3c(c2)OCO3)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 146 chemicals

3'-Hydroxy-5-methoxy-3,4-methylenedioxybiphenyl chemical structure, C14H12O4, CAS 136051-64-4
3'-Hydroxy-5-methoxy-3,4-methylenedioxybiphenyl
CAS 136051-64-4C14H12O4
3'-Hydroxy-5,5'-dimethoxy-3,4-methylenedioxybiphenyl chemical structure, C15H14O5, CAS 136051-65-5
3'-Hydroxy-5,5'-dimethoxy-3,4-methylenedioxybiphenyl
CAS 136051-65-5C15H14O5
1,3-Benzodioxole, 5-(4-methoxyphenyl)-6-propoxy- chemical structure, C17H18O4, CAS 77840-28-9
1,3-Benzodioxole, 5-(4-methoxyphenyl)-6-propoxy-
CAS 77840-28-9C17H18O4
Ismine chemical structure, C15H15NO3, CAS 1805-78-3
Ismine
CAS 1805-78-3C15H15NO3
2-[4-(1,3-Benzodioxol-5-yl)phenyl]sulfonylacetic acid chemical structure, C15H12O6S, CAS 653588-55-7
2-[4-(1,3-Benzodioxol-5-yl)phenyl]sulfonylacetic acid
CAS 653588-55-7C15H12O6S
6-Phenyl-1,3-benzodioxole-5-carbaldehyde chemical structure, C14H10O3, CAS 4432-95-5
6-Phenyl-1,3-benzodioxole-5-carbaldehyde
CAS 4432-95-5C14H10O3
2-(1,3-Benzodioxol-5-yl)-5-methoxybenzoic acid chemical structure, C15H12O5, CAS 854236-44-5
2-(1,3-Benzodioxol-5-yl)-5-methoxybenzoic acid
CAS 854236-44-5C15H12O5
2-(2-(Benzo[d][1,3]dioxol-5-yl)phenyl)acetic acid chemical structure, C15H12O4, CAS 669713-74-0
2-(2-(Benzo[d][1,3]dioxol-5-yl)phenyl)acetic acid
CAS 669713-74-0C15H12O4
3-Biphenyl-[1,3]dioxol-5-yl-acetic acid chemical structure, C15H12O4, CAS 669713-75-1
3-Biphenyl-[1,3]dioxol-5-yl-acetic acid
CAS 669713-75-1C15H12O4
4-Biphenyl-[1,3]dioxol-5-yl-acetic acid chemical structure, C15H12O4, CAS 669713-76-2
4-Biphenyl-[1,3]dioxol-5-yl-acetic acid
CAS 669713-76-2C15H12O4
2-(Benzo[d][1,3]dioxol-5-yl)Benzoic acid chemical structure, C14H10O4, CAS 24351-54-0
2-(Benzo[d][1,3]dioxol-5-yl)Benzoic acid
CAS 24351-54-0C14H10O4
3-Benzo[1,3]dioxol-5-yl-benzoic acid chemical structure, C14H10O4, CAS 24351-56-2
3-Benzo[1,3]dioxol-5-yl-benzoic acid
CAS 24351-56-2C14H10O4
4-(2H-1,3-Benzodioxol-5-yl)benzoic acid chemical structure, C14H10O4, CAS 193151-97-2
4-(2H-1,3-Benzodioxol-5-yl)benzoic acid
CAS 193151-97-2C14H10O4
5-(4-Fluorophenyl)-1,3-benzodioxole chemical structure, C13H9FO2, CAS 157790-85-7
5-(4-Fluorophenyl)-1,3-benzodioxole
CAS 157790-85-7C13H9FO2
1,3-Benzodioxole, 5-(4-methoxyphenyl)- chemical structure, C14H12O3, CAS 89346-90-7
1,3-Benzodioxole, 5-(4-methoxyphenyl)-
CAS 89346-90-7C14H12O3
4-(3,4-Methylenedioxyphenyl)phenol chemical structure, C13H10O3, CAS 220616-14-8
4-(3,4-Methylenedioxyphenyl)phenol
CAS 220616-14-8C13H10O3
Ethyl 4-(2H-1,3-benzodioxol-5-yl)benzoate chemical structure, C16H14O4, CAS 61097-62-9
Ethyl 4-(2H-1,3-benzodioxol-5-yl)benzoate
CAS 61097-62-9C16H14O4
2-({2-[4-(2H-1,3-Benzodioxol-5-yl)-2-tert-butylphenoxy]ethyl}(methyl)amino)acetic acid chemical structure, C22H27NO5, CAS 868265-28-5
2-({2-[4-(2H-1,3-Benzodioxol-5-yl)-2-tert-butylphenoxy]ethyl}(methyl)amino)acetic acid
CAS 868265-28-5C22H27NO5
2-(Benzo[d][1,3]dioxol-5-yl)-6-methylaniline chemical structure, C14H13NO2, CAS 849905-25-5
2-(Benzo[d][1,3]dioxol-5-yl)-6-methylaniline
CAS 849905-25-5C14H13NO2
1,3-Benzodioxole-5-carboxaldehyde, 6-(2-formylphenyl)- chemical structure, C15H10O4, CAS 61440-93-5
1,3-Benzodioxole-5-carboxaldehyde, 6-(2-formylphenyl)-
CAS 61440-93-5C15H10O4
1,3-Benzodioxole-5-carboxylic acid, 6-(2-methylphenyl)-, methyl ester chemical structure, C16H14O4, CAS 61441-07-4
1,3-Benzodioxole-5-carboxylic acid, 6-(2-methylphenyl)-, methyl ester
CAS 61441-07-4C16H14O4
6-[2-(Hydroxymethyl)phenyl]-2H-1,3-benzodioxole-5-carboxylic acid chemical structure, C15H12O5, CAS 61440-99-1
6-[2-(Hydroxymethyl)phenyl]-2H-1,3-benzodioxole-5-carboxylic acid
CAS 61440-99-1C15H12O5
5-(2-Methoxyphenyl)-2H-1,3-benzodioxole chemical structure, C14H12O3, CAS 89346-88-3
5-(2-Methoxyphenyl)-2H-1,3-benzodioxole
CAS 89346-88-3C14H12O3
5-Phenyl-2H-1,3-benzodioxole chemical structure, C13H10O2, CAS 24382-05-6
5-Phenyl-2H-1,3-benzodioxole
CAS 24382-05-6C13H10O2