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Murcko scaffold

Ring system with 3 rings and 20 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
5
With full pages
0
Scaffold SMILES

O=C(NCc1cccs1)c1ccn(-c2ccccc2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1cccs1)c1ccn(-c2ccccc2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

1-(4-Fluorophenyl)-4-methoxy-N-[(thiophen-2-yl)methyl]-1H-pyrazole-3-carboxamide chemical structure, C16H14FN3O2S, CAS 1020454-85-6
1-(4-Fluorophenyl)-4-methoxy-N-[(thiophen-2-yl)methyl]-1H-pyrazole-3-carboxamide
CAS 1020454-85-6C16H14FN3O2S
1-(4-Fluorophenyl)-4-propoxy-N-(thiophen-2-ylmethyl)-1H-pyrazole-3-carboxamide chemical structure, C18H18FN3O2S, CAS 1170976-05-2
1-(4-Fluorophenyl)-4-propoxy-N-(thiophen-2-ylmethyl)-1H-pyrazole-3-carboxamide
CAS 1170976-05-2C18H18FN3O2S
4-Ethoxy-1-(4-fluorophenyl)-N-(thiophen-2-ylmethyl)-1H-pyrazole-3-carboxamide chemical structure, C17H16FN3O2S, CAS 1189944-15-7
4-Ethoxy-1-(4-fluorophenyl)-N-(thiophen-2-ylmethyl)-1H-pyrazole-3-carboxamide
CAS 1189944-15-7C17H16FN3O2S
Methyl 2-(N-methyl-1-{5-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}formamido)-2-(thiophen-2-yl)acetate chemical structure, C20H18F3N3O3S, CAS 2761387-33-9
Methyl 2-(N-methyl-1-{5-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}formamido)-2-(thiophen-2-yl)acetate
CAS 2761387-33-9C20H18F3N3O3S
Orb3236195 chemical structure, C20H18F3N3O3S, CAS 3069879-24-6
Orb3236195
CAS 3069879-24-6C20H18F3N3O3S