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Murcko scaffold

N-(2-Phenylethyl)thiophene-2-sulfonamide scaffold

54 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
54
With full pages
6
Scaffold SMILES

O=S(=O)(NCCc1ccccc1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(2-Phenylethyl)thiophene-2-sulfonamide page
Murcko scaffold O=S(=O)(NCCc1ccccc1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 54 chemicals

N-(2-Thienylsulfonyl)-L-phenylalanine chemical structure, C13H13NO4S2, CAS 82068-17-5
N-(2-Thienylsulfonyl)-L-phenylalanine
CAS 82068-17-5C13H13NO4S2
N-(2-Phenylethyl)thiophene-2-sulfonamide chemical structure, C12H13NO2S2, CAS 332354-71-9
N-(2-Phenylethyl)thiophene-2-sulfonamide
CAS 332354-71-9C12H13NO2S2
N-[2-(4-Methoxyphenyl)ethyl]thiophene-2-sulfonamide chemical structure, C13H15NO3S2, CAS 321720-73-4
N-[2-(4-Methoxyphenyl)ethyl]thiophene-2-sulfonamide
CAS 321720-73-4C13H15NO3S2
5-Bromo-N-[2-(4-methoxyphenyl)ethyl]thiophene-2-sulfonamide chemical structure, C13H14BrNO3S2, CAS 676643-60-0
5-Bromo-N-[2-(4-methoxyphenyl)ethyl]thiophene-2-sulfonamide
CAS 676643-60-0C13H14BrNO3S2
N-[2-(4-Sulfamoylphenyl)ethyl]thiophene-2-sulfonamide chemical structure, C12H14N2O4S3, CAS 690247-62-2
N-[2-(4-Sulfamoylphenyl)ethyl]thiophene-2-sulfonamide
CAS 690247-62-2C12H14N2O4S3
(2S)-2-[3,5-Bis(methoxycarbonyl)-4-methylthiophene-2-sulfonamido]-3-phenylpropanoic acid chemical structure, C18H19NO8S2, CAS 1212193-10-6
(2S)-2-[3,5-Bis(methoxycarbonyl)-4-methylthiophene-2-sulfonamido]-3-phenylpropanoic acid
CAS 1212193-10-6C18H19NO8S2
3-Phenyl-2-(thiophene-2-sulfonylamino)-propionic acid chemical structure, C13H13NO4S2, CAS 82068-16-4
3-Phenyl-2-(thiophene-2-sulfonylamino)-propionic acid
CAS 82068-16-4C13H13NO4S2
2-[3,5-Bis(methoxycarbonyl)-4-methylthiophene-2-sulfonamido]-3-phenylpropanoic acid chemical structure, C18H19NO8S2, CAS 1007925-69-0
2-[3,5-Bis(methoxycarbonyl)-4-methylthiophene-2-sulfonamido]-3-phenylpropanoic acid
CAS 1007925-69-0C18H19NO8S2
N-(1-Hydroxy-1-phenylpropan-2-yl)-N-methylthiophene-2-sulfonamide chemical structure, C14H17NO3S2, CAS 379726-30-4
N-(1-Hydroxy-1-phenylpropan-2-yl)-N-methylthiophene-2-sulfonamide
CAS 379726-30-4C14H17NO3S2
Propionic acid, 3-(4-fluorophenyl)-2-(thiophene-2-sulfonylamino)- chemical structure, C13H12FNO4S2, CAS 1009524-90-6
Propionic acid, 3-(4-fluorophenyl)-2-(thiophene-2-sulfonylamino)-
CAS 1009524-90-6C13H12FNO4S2
N-(4-(Dimethylamino)phenethyl)thiophene-2-sulfonamide chemical structure, C14H18N2O2S2, CAS 952981-69-0
N-(4-(Dimethylamino)phenethyl)thiophene-2-sulfonamide
CAS 952981-69-0C14H18N2O2S2
5-Chloro-N-{2-[4-(dimethylamino)phenyl]ethyl}thiophene-2-sulfonamide chemical structure, C14H17ClN2O2S2, CAS 953941-75-8
5-Chloro-N-{2-[4-(dimethylamino)phenyl]ethyl}thiophene-2-sulfonamide
CAS 953941-75-8C14H17ClN2O2S2
N-(4-(Dimethylamino)phenethyl)-5-methylthiophene-2-sulfonamide chemical structure, C15H20N2O2S2, CAS 953941-87-2
N-(4-(Dimethylamino)phenethyl)-5-methylthiophene-2-sulfonamide
CAS 953941-87-2C15H20N2O2S2
N-(2-(Dimethylamino)-2-(p-tolyl)ethyl)thiophene-2-sulfonamide chemical structure, C15H20N2O2S2, CAS 899999-49-6
N-(2-(Dimethylamino)-2-(p-tolyl)ethyl)thiophene-2-sulfonamide
CAS 899999-49-6C15H20N2O2S2
5-Chloro-N-(2-(dimethylamino)-2-(4-fluorophenyl)ethyl)thiophene-2-sulfonamide chemical structure, C14H16ClFN2O2S2, CAS 941997-05-3
5-Chloro-N-(2-(dimethylamino)-2-(4-fluorophenyl)ethyl)thiophene-2-sulfonamide
CAS 941997-05-3C14H16ClFN2O2S2
N-(2-Amino-2-phenylethyl)-5-chlorothiophene-2-sulfonamide chemical structure, C12H13ClN2O2S2, CAS 1154670-17-3
N-(2-Amino-2-phenylethyl)-5-chlorothiophene-2-sulfonamide
CAS 1154670-17-3C12H13ClN2O2S2
N-(2-Amino-2-phenylethyl)thiophene-2-sulfonamide chemical structure, C12H14N2O2S2, CAS 1154217-26-1
N-(2-Amino-2-phenylethyl)thiophene-2-sulfonamide
CAS 1154217-26-1C12H14N2O2S2
5-Bromo-N-(2-hydroxy-2-phenylpropyl)thiophene-2-sulfonamide chemical structure, C13H14BrNO3S2, CAS 1351621-70-9
5-Bromo-N-(2-hydroxy-2-phenylpropyl)thiophene-2-sulfonamide
CAS 1351621-70-9C13H14BrNO3S2
N-{2-Hydroxy-2-[4-(trifluoromethyl)phenyl]ethyl}-5-methylthiophene-2-sulfonamide chemical structure, C14H14F3NO3S2, CAS 1351608-02-0
N-{2-Hydroxy-2-[4-(trifluoromethyl)phenyl]ethyl}-5-methylthiophene-2-sulfonamide
CAS 1351608-02-0C14H14F3NO3S2
5-Bromo-N-(2-hydroxy-2-(4-(trifluoromethyl)phenyl)ethyl)thiophene-2-sulfonamide chemical structure, C13H11BrF3NO3S2, CAS 1351647-91-0
5-Bromo-N-(2-hydroxy-2-(4-(trifluoromethyl)phenyl)ethyl)thiophene-2-sulfonamide
CAS 1351647-91-0C13H11BrF3NO3S2
N-(2-Amino-2-phenylethyl)-5-chlorothiophene-2-sulfonamide hydrochloride chemical structure, C12H14Cl2N2O2S2, CAS 1423033-13-9
N-(2-Amino-2-phenylethyl)-5-chlorothiophene-2-sulfonamide hydrochloride
CAS 1423033-13-9C12H14Cl2N2O2S2
N-(2-Amino-2-phenylethyl)thiophene-2-sulfonamide hydrochloride chemical structure, C12H15ClN2O2S2, CAS 1423033-23-1
N-(2-Amino-2-phenylethyl)thiophene-2-sulfonamide hydrochloride
CAS 1423033-23-1C12H15ClN2O2S2
5-Chloro-N-(3,3,3-trifluoro-2-hydroxy-2-phenylpropyl)thiophene-2-sulfonamide chemical structure, C13H11ClF3NO3S2, CAS 1351641-30-9
5-Chloro-N-(3,3,3-trifluoro-2-hydroxy-2-phenylpropyl)thiophene-2-sulfonamide
CAS 1351641-30-9C13H11ClF3NO3S2
N-{2-[4-(Dimethylamino)phenyl]-2-hydroxyethyl}thiophene-2-sulfonamide chemical structure, C14H18N2O3S2, CAS 1421455-34-6
N-{2-[4-(Dimethylamino)phenyl]-2-hydroxyethyl}thiophene-2-sulfonamide
CAS 1421455-34-6C14H18N2O3S2