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Murcko scaffold

Ring system with 3 rings and 22 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
10
With full pages
5
Scaffold SMILES

O=S(=O)(c1ccccc1)C1CCN(Cc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)C1CCN(Cc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Ethyl 4-(benzenesulfonyl)-1-[(4-chlorophenyl)methyl]piperidine-4-carboxylate chemical structure, C21H24ClNO4S, CAS 860649-14-5
Ethyl 4-(benzenesulfonyl)-1-[(4-chlorophenyl)methyl]piperidine-4-carboxylate
CAS 860649-14-5C21H24ClNO4S
Ethyl 4-(benzenesulfonyl)-1-[(4-methylphenyl)methyl]piperidine-4-carboxylate chemical structure, C22H27NO4S, CAS 860649-16-7
Ethyl 4-(benzenesulfonyl)-1-[(4-methylphenyl)methyl]piperidine-4-carboxylate
CAS 860649-16-7C22H27NO4S
Ethyl 4-(benzenesulfonyl)-1-benzylpiperidine-4-carboxylate chemical structure, C21H25NO4S, CAS 860649-17-8
Ethyl 4-(benzenesulfonyl)-1-benzylpiperidine-4-carboxylate
CAS 860649-17-8C21H25NO4S
Ethyl 1-(4-chlorobenzyl)-4-[(4-methoxyphenyl)sulfonyl]-4-piperidinecarboxylate chemical structure, C22H26ClNO5S, CAS 866135-91-3
Ethyl 1-(4-chlorobenzyl)-4-[(4-methoxyphenyl)sulfonyl]-4-piperidinecarboxylate
CAS 866135-91-3C22H26ClNO5S
Ethyl 4-[(4-chlorophenyl)sulfonyl]-1-(4-methylbenzyl)-4-piperidinecarboxylate chemical structure, C22H26ClNO4S, CAS 866150-05-2
Ethyl 4-[(4-chlorophenyl)sulfonyl]-1-(4-methylbenzyl)-4-piperidinecarboxylate
CAS 866150-05-2C22H26ClNO4S
Ethyl 1-benzyl-4-(4-methoxyphenyl)sulfonylpiperidine-4-carboxylate chemical structure, C22H27NO5S, CAS 212770-54-2
Ethyl 1-benzyl-4-(4-methoxyphenyl)sulfonylpiperidine-4-carboxylate
CAS 212770-54-2C22H27NO5S
Ethyl 4-(4-methoxyphenyl)sulfonyl-1-[(4-methylphenyl)methyl]piperidine-4-carboxylate chemical structure, C23H29NO5S, CAS 212770-64-4
Ethyl 4-(4-methoxyphenyl)sulfonyl-1-[(4-methylphenyl)methyl]piperidine-4-carboxylate
CAS 212770-64-4C23H29NO5S
1-[(4-Chlorophenyl)methyl]-4-(4-chlorophenyl)sulfonyl-4-piperidinecarboxylic acid ethyl ester chemical structure, C21H23Cl2NO4S, CAS 866150-04-1
1-[(4-Chlorophenyl)methyl]-4-(4-chlorophenyl)sulfonyl-4-piperidinecarboxylic acid ethyl ester
CAS 866150-04-1C21H23Cl2NO4S
Ethyl 1-benzyl-4-[(4-chlorophenyl)sulfonyl]-4-piperidinecarboxylate chemical structure, C21H24ClNO4S, CAS 866150-03-0
Ethyl 1-benzyl-4-[(4-chlorophenyl)sulfonyl]-4-piperidinecarboxylate
CAS 866150-03-0C21H24ClNO4S
Ethyl 1-(4-methoxybenzyl)-4-[(4-methoxyphenyl)sulfonyl]-4-piperidinecarboxylate chemical structure, C23H29NO6S, CAS 212771-00-1
Ethyl 1-(4-methoxybenzyl)-4-[(4-methoxyphenyl)sulfonyl]-4-piperidinecarboxylate
CAS 212771-00-1C23H29NO6S