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Murcko scaffold

Ring system with 3 rings and 19 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
12
With full pages
2
Scaffold SMILES

O=C1OC(c2ccccc2)=NC1=Cc1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OC(c2ccccc2)=NC1=Cc1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

2-Phenyl-4-(pyridin-3-ylmethylene)oxazol-5(4H)-one chemical structure, C15H10N2O2, CAS 5086-43-1
2-Phenyl-4-(pyridin-3-ylmethylene)oxazol-5(4H)-one
CAS 5086-43-1C15H10N2O2
(E)-2-(3,4-Dimethoxyphenyl)-4-(pyridin-3-ylmethylene)oxazol-5(4H)-one chemical structure, C17H14N2O4, CAS 304000-05-3
(E)-2-(3,4-Dimethoxyphenyl)-4-(pyridin-3-ylmethylene)oxazol-5(4H)-one
CAS 304000-05-3C17H14N2O4
Dapk-IN-2 chemical structure, C17H14N2O4
Dapk-IN-2
C17H14N2O4
2-(3,4-Dimethoxyphenyl)-4-(pyridin-3-ylmethylene)oxazol-5(4H)-one chemical structure, C17H14N2O4
2-(3,4-Dimethoxyphenyl)-4-(pyridin-3-ylmethylene)oxazol-5(4H)-one
C17H14N2O4
5(4H)-Oxazolone, 2-(3-bromophenyl)-4-(3-pyridinylmethylene)- chemical structure, C15H9BrN2O2, CAS 299166-09-9
5(4H)-Oxazolone, 2-(3-bromophenyl)-4-(3-pyridinylmethylene)-
CAS 299166-09-9C15H9BrN2O2
4-(3-Pyridinylmethylene)-2-(3,4,5-trimethoxyphenyl)-5(4H)-oxazolone chemical structure, C18H16N2O5, CAS 299933-45-2
4-(3-Pyridinylmethylene)-2-(3,4,5-trimethoxyphenyl)-5(4H)-oxazolone
CAS 299933-45-2C18H16N2O5
4-Pyridin-3-ylmethylene-2-m-tolyl-4H-oxazol-5-one chemical structure, C16H12N2O2, CAS 313970-78-4
4-Pyridin-3-ylmethylene-2-m-tolyl-4H-oxazol-5-one
CAS 313970-78-4C16H12N2O2
(4Z)-2-(4-tert-Butylphenyl)-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one chemical structure, C19H18N2O2, CAS 5376-30-7
(4Z)-2-(4-tert-Butylphenyl)-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one
CAS 5376-30-7C19H18N2O2
(4E)-2-(3-Methoxyphenyl)-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one chemical structure, C16H12N2O3, CAS 299938-12-8
(4E)-2-(3-Methoxyphenyl)-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one
CAS 299938-12-8C16H12N2O3
2-(2-Chloro-4-methoxyphenyl)-4-[(pyridin-3-yl)methylidene]-4,5-dihydro-1,3-oxazol-5-one chemical structure, C16H11ClN2O3, CAS 388579-29-1
2-(2-Chloro-4-methoxyphenyl)-4-[(pyridin-3-yl)methylidene]-4,5-dihydro-1,3-oxazol-5-one
CAS 388579-29-1C16H11ClN2O3
(4Z)-2-(4-Chloro-3-nitrophenyl)-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one chemical structure, C15H8ClN3O4, CAS 313971-05-0
(4Z)-2-(4-Chloro-3-nitrophenyl)-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one
CAS 313971-05-0C15H8ClN3O4
4-[(2-Chloropyridin-3-yl)methylene]-2-phenyl-1,3-oxazol-5(4H)-one chemical structure, C15H9ClN2O2, CAS 1417367-13-5
4-[(2-Chloropyridin-3-yl)methylene]-2-phenyl-1,3-oxazol-5(4H)-one
CAS 1417367-13-5C15H9ClN2O2