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Murcko scaffold

Ring system with 3 rings and 16 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
8
With full pages
3
Scaffold SMILES

c1ccc(Sc2nc3ncncc3[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Sc2nc3ncncc3[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

8-(4-Chlorophenylthio)adenine chemical structure, C11H8ClN5S, CAS 696574-61-5
8-(4-Chlorophenylthio)adenine
CAS 696574-61-5C11H8ClN5S
1H-Purin-6-amine, 8-[(3,4,5-trimethoxyphenyl)thio]- chemical structure, C14H15N5O3S, CAS 827302-37-4
1H-Purin-6-amine, 8-[(3,4,5-trimethoxyphenyl)thio]-
CAS 827302-37-4C14H15N5O3S
8-(2,4-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine chemical structure, C18H19N5S, CAS 852030-37-6
8-(2,4-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine
CAS 852030-37-6C18H19N5S
8-((2,4-Dichlorophenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine chemical structure, C16H13Cl2N5S, CAS 852030-38-7
8-((2,4-Dichlorophenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine
CAS 852030-38-7C16H13Cl2N5S
8-[(3-Methoxyphenyl)sulfanyl]-7H-purin-6-amine chemical structure, C12H11N5OS, CAS 696574-58-0
8-[(3-Methoxyphenyl)sulfanyl]-7H-purin-6-amine
CAS 696574-58-0C12H11N5OS
9-(4-Pentyn-1-yl)-8-[(2,4,6-trimethylphenyl)thio]-9H-purin-6-amine chemical structure, C19H21N5S, CAS 1454619-17-0
9-(4-Pentyn-1-yl)-8-[(2,4,6-trimethylphenyl)thio]-9H-purin-6-amine
CAS 1454619-17-0C19H21N5S
8-((3,5-Dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine chemical structure, C17H20Cl2N6S, CAS 1454619-14-7
8-((3,5-Dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
CAS 1454619-14-7C17H20Cl2N6S
(3-(6-Amino-9-butyl-9H-purin-8-ylthio)phenyl)methanol chemical structure, C16H19N5OS, CAS 1404364-85-7
(3-(6-Amino-9-butyl-9H-purin-8-ylthio)phenyl)methanol
CAS 1404364-85-7C16H19N5OS