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Murcko scaffold

Ring system with 3 rings and 19 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
9
With full pages
3
Scaffold SMILES

C1=C(Nc2ccccc2)CCCC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=C(Nc2ccccc2)CCCC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1-[3-Acetyl-6-hydroxy-6-methyl-4-(4-methylanilino)-2-phenylcyclohex-3-en-1-yl]ethanone chemical structure, C24H27NO3, CAS 161265-86-7
1-[3-Acetyl-6-hydroxy-6-methyl-4-(4-methylanilino)-2-phenylcyclohex-3-en-1-yl]ethanone
CAS 161265-86-7C24H27NO3
Diethyl 6-hydroxy-6-methyl-4-[(4-methylphenyl)amino]-2-phenyl-3-cyclohexene-1,3-dicarboxylate chemical structure, C26H31NO5, CAS 161265-88-9
Diethyl 6-hydroxy-6-methyl-4-[(4-methylphenyl)amino]-2-phenyl-3-cyclohexene-1,3-dicarboxylate
CAS 161265-88-9C26H31NO5
1-(3-Acetyl-4-(4-bromoanilino)-6-hydroxy-2-{4-nitrophenyl}-6-methylcyclohex-3-en-1-yl)ethanone chemical structure, C23H23BrN2O5, CAS 499100-18-4
1-(3-Acetyl-4-(4-bromoanilino)-6-hydroxy-2-{4-nitrophenyl}-6-methylcyclohex-3-en-1-yl)ethanone
CAS 499100-18-4C23H23BrN2O5
1-[3-Acetyl-4-anilino-6-hydroxy-2-(4-methoxyphenyl)-6-methylcyclohex-3-en-1-yl]ethanone chemical structure, C24H27NO4, CAS 473264-93-6
1-[3-Acetyl-4-anilino-6-hydroxy-2-(4-methoxyphenyl)-6-methylcyclohex-3-en-1-yl]ethanone
CAS 473264-93-6C24H27NO4
1-[3-Acetyl-4-anilino-2-(4-fluorophenyl)-6-hydroxy-6-methylcyclohex-3-en-1-yl]ethanone chemical structure, C23H24FNO3, CAS 473265-03-1
1-[3-Acetyl-4-anilino-2-(4-fluorophenyl)-6-hydroxy-6-methylcyclohex-3-en-1-yl]ethanone
CAS 473265-03-1C23H24FNO3
1-(3-Acetyl-4-anilino-6-hydroxy-6-methyl-2-phenylcyclohex-3-en-1-yl)ethanone chemical structure, C23H25NO3, CAS 161265-85-6
1-(3-Acetyl-4-anilino-6-hydroxy-6-methyl-2-phenylcyclohex-3-en-1-yl)ethanone
CAS 161265-85-6C23H25NO3
1-[3-Acetyl-4-anilino-2-(2-fluorophenyl)-6-hydroxy-6-methylcyclohex-3-en-1-yl]ethanone chemical structure, C23H24FNO3, CAS 473265-19-9
1-[3-Acetyl-4-anilino-2-(2-fluorophenyl)-6-hydroxy-6-methylcyclohex-3-en-1-yl]ethanone
CAS 473265-19-9C23H24FNO3
1-[3-Acetyl-4-anilino-2-(4-chlorophenyl)-6-hydroxy-6-methylcyclohex-3-en-1-yl]ethanone chemical structure, C23H24ClNO3, CAS 473265-00-8
1-[3-Acetyl-4-anilino-2-(4-chlorophenyl)-6-hydroxy-6-methylcyclohex-3-en-1-yl]ethanone
CAS 473265-00-8C23H24ClNO3
Diethyl 4-anilino-2-(4-bromophenyl)-6-hydroxy-6-methyl-3-cyclohexene-1,3-dicarboxylate chemical structure, C25H28BrNO5, CAS 317342-27-1
Diethyl 4-anilino-2-(4-bromophenyl)-6-hydroxy-6-methyl-3-cyclohexene-1,3-dicarboxylate
CAS 317342-27-1C25H28BrNO5