CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 16 atoms

124 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
124
With full pages
16
Scaffold SMILES

O=C(COc1ccccc1)Nc1nncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)Nc1nncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 124 chemicals

N-[5-(Propan-2-yl)-1,3,4-thiadiazol-2-yl]-2-(2,3,6-trimethylphenoxy)acetamide chemical structure, C16H21N3O2S, CAS 433261-67-7
N-[5-(Propan-2-yl)-1,3,4-thiadiazol-2-yl]-2-(2,3,6-trimethylphenoxy)acetamide
CAS 433261-67-7C16H21N3O2S
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(4-methylphenoxy)acetamide chemical structure, C13H15N3O2S, CAS 57628-28-1
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(4-methylphenoxy)acetamide
CAS 57628-28-1C13H15N3O2S
2-(4-Chlorophenoxy)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C12H12ClN3O2S, CAS 57628-24-7
2-(4-Chlorophenoxy)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 57628-24-7C12H12ClN3O2S
2-(4-Chlorophenoxy)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C13H14ClN3O2S, CAS 316127-85-2
2-(4-Chlorophenoxy)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)acetamide
CAS 316127-85-2C13H14ClN3O2S
2-(2,4-Dimethylphenoxy)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C13H15N3O2S, CAS 329225-03-8
2-(2,4-Dimethylphenoxy)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 329225-03-8C13H15N3O2S
2-(3-Methyl-4-propan-2-ylphenoxy)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C17H23N3O2S, CAS 347364-63-0
2-(3-Methyl-4-propan-2-ylphenoxy)-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)acetamide
CAS 347364-63-0C17H23N3O2S
2-(2-tert-Butyl-4-methylphenoxy)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C16H21N3O2S, CAS 452362-65-1
2-(2-tert-Butyl-4-methylphenoxy)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 452362-65-1C16H21N3O2S
2-(2-tert-Butylphenoxy)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C15H19N3O2S, CAS 347363-91-1
2-(2-tert-Butylphenoxy)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 347363-91-1C15H19N3O2S
2-(2-Ethoxyphenoxy)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C13H15N3O3S, CAS 452362-69-5
2-(2-Ethoxyphenoxy)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 452362-69-5C13H15N3O3S
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(2-nitrophenoxy)acetamide chemical structure, C12H12N4O4S, CAS 307544-94-1
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(2-nitrophenoxy)acetamide
CAS 307544-94-1C12H12N4O4S
2-(2,4-Dichlorophenoxy)-N-(5-isopropyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C13H13Cl2N3O2S, CAS 369395-05-1
2-(2,4-Dichlorophenoxy)-N-(5-isopropyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 369395-05-1C13H13Cl2N3O2S
2-(3-Chloro-phenoxy)-N-(5-isopropyl-[1,3,4]thiadiazol-2-yl)-acetamide chemical structure, C13H14ClN3O2S, CAS 307544-97-4
2-(3-Chloro-phenoxy)-N-(5-isopropyl-[1,3,4]thiadiazol-2-yl)-acetamide
CAS 307544-97-4C13H14ClN3O2S
2-(2-Nitrophenoxy)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C13H14N4O4S, CAS 307544-98-5
2-(2-Nitrophenoxy)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 307544-98-5C13H14N4O4S
N-[(2Z)-5-Ethyl-1,3,4-thiadiazol-2(3H)-ylidene]-2-[3-methyl-4-(propan-2-yl)phenoxy]acetamide chemical structure, C16H21N3O2S, CAS 333747-41-4
N-[(2Z)-5-Ethyl-1,3,4-thiadiazol-2(3H)-ylidene]-2-[3-methyl-4-(propan-2-yl)phenoxy]acetamide
CAS 333747-41-4C16H21N3O2S
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-(2,3,6-trimethylphenoxy)acetamide chemical structure, C14H17N3O2S, CAS 433322-25-9
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-(2,3,6-trimethylphenoxy)acetamide
CAS 433322-25-9C14H17N3O2S
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(2,3,6-trimethylphenoxy)acetamide chemical structure, C15H19N3O2S, CAS 385387-05-3
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(2,3,6-trimethylphenoxy)acetamide
CAS 385387-05-3C15H19N3O2S
2-(4-Chloro-3-methylphenoxy)-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C13H14ClN3O3S, CAS 667903-37-9
2-(4-Chloro-3-methylphenoxy)-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 667903-37-9C13H14ClN3O3S
2-(2-Chlorophenoxy)-N-(1,3,4-thiadiazol-2-yl)acetamide chemical structure, C10H8ClN3O2S, CAS 685549-68-2
2-(2-Chlorophenoxy)-N-(1,3,4-thiadiazol-2-yl)acetamide
CAS 685549-68-2C10H8ClN3O2S
2-(2-tert-Butylphenoxy)-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C16H21N3O3S, CAS 685553-28-0
2-(2-tert-Butylphenoxy)-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 685553-28-0C16H21N3O3S
2-(4-tert-Butylphenoxy)-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C16H21N3O3S, CAS 685553-44-0
2-(4-tert-Butylphenoxy)-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 685553-44-0C16H21N3O3S
2-(2,5-Dimethylphenoxy)-N-(1,3,4-thiadiazol-2-yl)acetamide chemical structure, C12H13N3O2S, CAS 685557-97-5
2-(2,5-Dimethylphenoxy)-N-(1,3,4-thiadiazol-2-yl)acetamide
CAS 685557-97-5C12H13N3O2S
2-(2,4-Dichlorophenoxy)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C12H11Cl2N3O2S, CAS 57628-25-8
2-(2,4-Dichlorophenoxy)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 57628-25-8C12H11Cl2N3O2S
N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-2-(4-chlorophenoxy)acetamide chemical structure, C14H16ClN3O2S, CAS 432515-24-7
N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-2-(4-chlorophenoxy)acetamide
CAS 432515-24-7C14H16ClN3O2S
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-phenoxyacetamide chemical structure, C11H11N3O2S, CAS 57628-17-8
N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-phenoxyacetamide
CAS 57628-17-8C11H11N3O2S