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Murcko scaffold

1-(1-Benzofuran-2-carbonyl)piperazine scaffold

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
20
With full pages
3
Scaffold SMILES

O=C(c1cc2ccccc2o1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(1-Benzofuran-2-carbonyl)piperazine page
Murcko scaffold O=C(c1cc2ccccc2o1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

Ketone, 4-methyl-1-piperazinyl 3-methyl-5,6-7-trimethoxy-2-benzofuranyl, hydrochloride chemical structure, C18H25ClN2O5, CAS 63446-00-4
Ketone, 4-methyl-1-piperazinyl 3-methyl-5,6-7-trimethoxy-2-benzofuranyl, hydrochloride
CAS 63446-00-4C18H25ClN2O5
Piperazine, 1-((6-methoxy-3-methylbenzofuran-2-yl)carbonyl)-4-methyl-, hydrochloride chemical structure, C16H21ClN2O3, CAS 35689-00-0
Piperazine, 1-((6-methoxy-3-methylbenzofuran-2-yl)carbonyl)-4-methyl-, hydrochloride
CAS 35689-00-0C16H21ClN2O3
Piperazine, 1-((5-bromo-6-methoxy-3-methylbenzofuran-2-yl)carbonyl)-4-methyl-, hydrochloride chemical structure, C16H20BrClN2O3, CAS 35689-01-1
Piperazine, 1-((5-bromo-6-methoxy-3-methylbenzofuran-2-yl)carbonyl)-4-methyl-, hydrochloride
CAS 35689-01-1C16H20BrClN2O3
Piperazine, 1-((5,7-dibromo-6-methoxy-3-methylbenzofuran-2-yl)carbonyl)-4-methyl-, hydrochloride chemical structure, C16H19Br2ClN2O3, CAS 35689-02-2
Piperazine, 1-((5,7-dibromo-6-methoxy-3-methylbenzofuran-2-yl)carbonyl)-4-methyl-, hydrochloride
CAS 35689-02-2C16H19Br2ClN2O3
Piperazine, 1-((5,6-dimethoxy-3-methyl-2-benzofuranyl)carbonyl)-4-methyl-, monohydrochloride chemical structure, C17H23ClN2O4, CAS 40713-12-0
Piperazine, 1-((5,6-dimethoxy-3-methyl-2-benzofuranyl)carbonyl)-4-methyl-, monohydrochloride
CAS 40713-12-0C17H23ClN2O4
Piperazine, 1-((6,7-dimethoxy-3-methyl-2-benzofuranyl)carbonyl)-4-methyl-, monohydrochloride chemical structure, C17H23ClN2O4, CAS 40713-19-7
Piperazine, 1-((6,7-dimethoxy-3-methyl-2-benzofuranyl)carbonyl)-4-methyl-, monohydrochloride
CAS 40713-19-7C17H23ClN2O4
Piperazine, 1-((6,7-diethoxy-3-methyl-2-benzofuranyl)carbonyl)-4-methyl-, monohydrochloride chemical structure, C19H27ClN2O4, CAS 40713-23-3
Piperazine, 1-((6,7-diethoxy-3-methyl-2-benzofuranyl)carbonyl)-4-methyl-, monohydrochloride
CAS 40713-23-3C19H27ClN2O4
(4-Methylpiperazin-1-yl)-(3,5,6-trimethyl-1-benzofuran-2-yl)methanone chemical structure, C17H22N2O2, CAS 622349-19-3
(4-Methylpiperazin-1-yl)-(3,5,6-trimethyl-1-benzofuran-2-yl)methanone
CAS 622349-19-3C17H22N2O2
(5-Chloro-3-methyl-1-benzofuran-2-yl)-(4-methylpiperazin-1-yl)methanone chemical structure, C15H17ClN2O2, CAS 714261-35-5
(5-Chloro-3-methyl-1-benzofuran-2-yl)-(4-methylpiperazin-1-yl)methanone
CAS 714261-35-5C15H17ClN2O2
Ethyl 4-[5-(diethylsulfamoyl)-3-methyl-1-benzofuran-2-carbonyl]piperazine-1-carboxylate chemical structure, C21H29N3O6S, CAS 687568-35-0
Ethyl 4-[5-(diethylsulfamoyl)-3-methyl-1-benzofuran-2-carbonyl]piperazine-1-carboxylate
CAS 687568-35-0C21H29N3O6S
(3-Methyl-1-benzofuran-2-yl)-(4-prop-2-enylpiperazin-1-yl)methanone chemical structure, C17H20N2O2, CAS 886641-75-4
(3-Methyl-1-benzofuran-2-yl)-(4-prop-2-enylpiperazin-1-yl)methanone
CAS 886641-75-4C17H20N2O2
(7-Chloro-3-methyl-1-benzofuran-2-yl)(4-propylpiperazin-1-yl)methanone chemical structure, C17H21ClN2O2, CAS 930543-24-1
(7-Chloro-3-methyl-1-benzofuran-2-yl)(4-propylpiperazin-1-yl)methanone
CAS 930543-24-1C17H21ClN2O2
1-(1-Benzofuran-2-carbonyl)piperazine chemical structure, C13H14N2O2, CAS 41717-31-1
1-(1-Benzofuran-2-carbonyl)piperazine
CAS 41717-31-1C13H14N2O2
(7-Methoxybenzofuran-2-yl)(4-(methylsulfonyl)piperazin-1-yl)methanone chemical structure, C15H18N2O5S, CAS 1203234-61-0
(7-Methoxybenzofuran-2-yl)(4-(methylsulfonyl)piperazin-1-yl)methanone
CAS 1203234-61-0C15H18N2O5S
1-(1-Benzofuran-2-carbonyl)piperazine hydrochloride chemical structure, C13H15ClN2O2, CAS 1239983-17-5
1-(1-Benzofuran-2-carbonyl)piperazine hydrochloride
CAS 1239983-17-5C13H15ClN2O2
tert-Butyl 4-(3-methyl-1-benzofuran-2-carbonyl)piperazine-1-carboxylate chemical structure, C19H24N2O4, CAS 1331060-83-3
tert-Butyl 4-(3-methyl-1-benzofuran-2-carbonyl)piperazine-1-carboxylate
CAS 1331060-83-3C19H24N2O4
(7-Chlorobenzofuran-2-yl)(4-methylpiperazin-1-yl)methanone chemical structure, C14H15ClN2O2, CAS 1204969-10-7
(7-Chlorobenzofuran-2-yl)(4-methylpiperazin-1-yl)methanone
CAS 1204969-10-7C14H15ClN2O2
(4-(2-Hydroxypropyl)piperazin-1-yl)(7-methoxybenzofuran-2-yl)methanone hydrochloride chemical structure, C17H23ClN2O4, CAS 1396800-52-4
(4-(2-Hydroxypropyl)piperazin-1-yl)(7-methoxybenzofuran-2-yl)methanone hydrochloride
CAS 1396800-52-4C17H23ClN2O4
4-(1-Benzofuran-2-carbonyl)piperazine-1-sulfonyl fluoride chemical structure, C13H13FN2O4S, CAS 2411276-82-7
4-(1-Benzofuran-2-carbonyl)piperazine-1-sulfonyl fluoride
CAS 2411276-82-7C13H13FN2O4S
1-(7-Methoxy-1-benzofuran-2-carbonyl)-4-(2,2,2-trifluoroethyl)piperazine chemical structure, C16H17F3N2O3, CAS 2742030-20-0
1-(7-Methoxy-1-benzofuran-2-carbonyl)-4-(2,2,2-trifluoroethyl)piperazine
CAS 2742030-20-0C16H17F3N2O3