Murcko scaffold
Benzyl 2-naphthyl ether scaffold
158 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 158
- With full pages
- 13
Scaffold SMILES
c1ccc(COc2ccc3ccccc3c2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 158 chemicals
Benzyl 2-naphthyl ether
CAS 613-62-7C17H14O
2-Benzyloxy-1-bromonaphthalene
CAS 41908-23-0C17H13BrO
Methyl 3-((naphthalen-2-yloxy)methyl)benzoate
CAS 438464-66-5C19H16O3
2-(Benzyloxy)-6-bromonaphthalene
CAS 2234-45-9C17H13BrO
2-(Benzyloxy)-1-naphthaldehyde
CAS 52805-48-8C18H14O2
![2-[(2,4-Dichlorobenzyl)oxy]-1-naphthaldehyde chemical structure, C18H12Cl2O2, CAS 321432-08-0](/s/MBLSKTHLXLXJBL-UHFFFAOYSA-N.svg)
2-[(2,4-Dichlorobenzyl)oxy]-1-naphthaldehyde
CAS 321432-08-0C18H12Cl2O2
![2-[(4-Fluorophenyl)methoxy]naphthalene-1-carbaldehyde chemical structure, C18H13FO2, CAS 428488-64-6](/s/JPEHUIDBDPYUHT-UHFFFAOYSA-N.svg)
2-[(4-Fluorophenyl)methoxy]naphthalene-1-carbaldehyde
CAS 428488-64-6C18H13FO2
![3-[(Naphthalen-2-yloxy)methyl]benzoic acid chemical structure, C18H14O3, CAS 438464-01-8](/s/AVUARZXMXUBPBN-UHFFFAOYSA-N.svg)
3-[(Naphthalen-2-yloxy)methyl]benzoic acid
CAS 438464-01-8C18H14O3
1-(2-(Benzyloxy)naphthalen-1-yl)-N-methylmethanamine
CAS 774547-31-8C19H19NO
![4-[(Naphthalen-2-yloxy)methyl]benzohydrazide chemical structure, C18H16N2O2, CAS 377769-56-7](/s/JTTUPOZCHZRWSQ-UHFFFAOYSA-N.svg)
4-[(Naphthalen-2-yloxy)methyl]benzohydrazide
CAS 377769-56-7C18H16N2O2
![4-Methoxy-3-[(2-naphthyloxy)methyl]benzaldehyde chemical structure, C19H16O3, CAS 438531-00-1](/s/QDIZDXPFRYFCMC-UHFFFAOYSA-N.svg)
4-Methoxy-3-[(2-naphthyloxy)methyl]benzaldehyde
CAS 438531-00-1C19H16O3
![2-[(3-Fluorobenzyl)oxy]naphthalene-1-carbaldehyde chemical structure, C18H13FO2, CAS 693237-44-4](/s/WTIXPLCGGSFWEY-UHFFFAOYSA-N.svg)
2-[(3-Fluorobenzyl)oxy]naphthalene-1-carbaldehyde
CAS 693237-44-4C18H13FO2
4-(Naphthalen-2-yloxymethyl)benzoic acid
CAS 149288-37-9C18H14O3
![2-[(3-Methylbenzyl)oxy]naphthalene-1-carbaldehyde chemical structure, C19H16O2, CAS 662159-46-8](/s/FYDZGDSONUFWFZ-UHFFFAOYSA-N.svg)
2-[(3-Methylbenzyl)oxy]naphthalene-1-carbaldehyde
CAS 662159-46-8C19H16O2
2-(Benzyloxy)-1-naphthoic Acid
CAS 93655-27-7C18H14O3
![2,2,2-Trifluoroethyl 3-[(2-naphthyloxy)methyl]benzoate chemical structure, C20H15F3O3, CAS 438471-50-2](/s/CLUPORXXUBNDNO-UHFFFAOYSA-N.svg)
2,2,2-Trifluoroethyl 3-[(2-naphthyloxy)methyl]benzoate
CAS 438471-50-2C20H15F3O3
![{[2-(Benzyloxy)-1-naphthyl]methylene}(methyl)ammoniumolate chemical structure, C19H17NO2, CAS 338422-64-3](/s/QLDFNOKHFYVIHI-MOSHPQCFSA-N.svg)
{[2-(Benzyloxy)-1-naphthyl]methylene}(methyl)ammoniumolate
CAS 338422-64-3C19H17NO2
![2-{[3-(Trifluoromethyl)benzyl]oxy}-1-naphthaldehyde chemical structure, C19H13F3O2, CAS 866133-96-2](/s/QVYBAIFKYHLJAB-UHFFFAOYSA-N.svg)
2-{[3-(Trifluoromethyl)benzyl]oxy}-1-naphthaldehyde
CAS 866133-96-2C19H13F3O2
3-(6-Benzyloxy-naphthalen-2-yl)-acrylic acid methyl ester
CAS 851124-28-2C21H18O3
![2-[(2-Fluorophenyl)methoxy]naphthalene-1-carbaldehyde chemical structure, C18H13FO2, CAS 725276-88-0](/s/HLLJGANAKWVJRF-UHFFFAOYSA-N.svg)
2-[(2-Fluorophenyl)methoxy]naphthalene-1-carbaldehyde
CAS 725276-88-0C18H13FO2
![2-[(2-Fluorophenyl)methoxy]-1-naphthalenemethanol chemical structure, C18H15FO2, CAS 690969-17-6](/s/DPFDAOQBAAHENV-UHFFFAOYSA-N.svg)
2-[(2-Fluorophenyl)methoxy]-1-naphthalenemethanol
CAS 690969-17-6C18H15FO2
![2-[(2-Phenylmethoxynaphthalen-1-yl)methylamino]ethanol chemical structure, C20H21NO2, CAS 861412-62-6](/s/BHRGBUQJSKOLMX-UHFFFAOYSA-N.svg)
2-[(2-Phenylmethoxynaphthalen-1-yl)methylamino]ethanol
CAS 861412-62-6C20H21NO2
![2-[({2-[(2-Chlorobenzyl)oxy]-1-naphthyl}methyl)amino]ethanol chemical structure, C20H20ClNO2, CAS 860607-46-1](/s/WBGGNOZILOTQSC-UHFFFAOYSA-N.svg)
2-[({2-[(2-Chlorobenzyl)oxy]-1-naphthyl}methyl)amino]ethanol
CAS 860607-46-1C20H20ClNO2
![N-({2-[(2-Fluorobenzyl)oxy]-1-naphthyl}methyl)-N-methylamine chemical structure, C19H18FNO, CAS 796887-52-0](/s/WUXPIHKVMXGSCO-UHFFFAOYSA-N.svg)
N-({2-[(2-Fluorobenzyl)oxy]-1-naphthyl}methyl)-N-methylamine
CAS 796887-52-0C19H18FNO
- N-({2-[(4-Fluorobenzyl)oxy]-1-naphthyl}methyl)-N-methylamine774546-18-8C19H18FNO
- 7-(Benzyloxy)naphthalen-2-ol118495-07-1C17H14O2
- 6-Benzyloxy-2-naphthylboronic acid152915-83-8C17H15BO3
- 2-[[2-[(2,4-Dichlorophenyl)methoxy]naphthalen-1-yl]methylamino]ethanol774191-94-5C20H19Cl2NO2
- 1-(2-(Benzyloxy)naphthalen-1-yl)-N-methylmethanamine hydrochloride1052516-41-2C19H20ClNO
- 2-[(4-Chlorobenzyl)oxy]naphthalene-1-carbaldehyde710296-44-9C18H13ClO2
- 2-[(4-Methylphenyl)methoxy]naphthalene-1-carbaldehyde149833-94-3C19H16O2
- Alpha,alpha-dimethyl-4-nitrobenzyl 1-methyl-2-naphthyl ether14851-08-2C20H19NO3
- 3-((2-Naphthalenyloxy)methyl)benzoic acid hydrazide438474-99-8C18H16N2O2
- (2-Naphthyloxy)(phenyl)acetic acid875820-12-5C18H14O3
- N-[3-(Dimethylamino)propyl]-3-(naphthalen-2-yloxymethyl)benzamide438474-52-3C23H26N2O2
- 2-[[2-[(2-Fluorophenyl)methoxy]naphthalen-1-yl]methylamino]ethanol880068-01-9C20H20FNO2
- 1-[({2-[(2-Fluorobenzyl)oxy]-1-naphthyl}methyl)amino]-2-propanol880068-17-7C21H22FNO2
- 1-[({2-[(2-Chlorobenzyl)oxy]naphthalen-1-yl}methyl)amino]propan-2-ol893572-10-6C21H22ClNO2
- 2-[(2,4-Dichlorophenyl)methoxy]-N-pentyl-1-naphthalenemethanamine893586-27-1C23H25Cl2NO
- (2-(Benzyloxy)naphthalen-1-yl)methanol217176-35-7C18H16O2
- 2-[(2-Chlorophenyl)methoxy]naphthalene-1-carbaldehyde710296-47-2C18H13ClO2
- ({2-[(2,4-Dichlorobenzyl)oxy]-1-naphthyl}methylene)(methyl)ammoniumolate321432-09-1C19H15Cl2NO2
- [(E)-[(2-{[3-(Trifluoromethyl)phenyl]methoxy}naphthalen-1-yl)methylidene]amino]thiourea866138-16-1C20H16F3N3OS
- 3-(Benzyloxy)naphthalene-2-carbaldehyde220328-44-9C18H14O2
- 2-Naphthalenecarbonitrile, 6-(phenylmethoxy)-66217-29-6C18H13NO
- 2-Naphthalenol, 3-(phenylmethoxy)-98793-02-3C17H14O2
- 2-Benzyloxy-1-bromo-6-methoxy-naphthalene648904-47-6C18H15BrO2
- 1-Naphthalenecarboxylic acid, 2-(phenylmethoxy)-, methyl ester512786-26-4C19H16O3
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(N=Nc2ccc3ccccc3c2)cc167 chemicals![Scaffold O=C(Nc1ccccc1)c1cc2ccccc2[nH]c1=O](/scaffold/DZOOMZBMCVCDDF-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1cc2ccccc2[nH]c1=O61 chemicals
O=C(Nc1ccccc1)c1ccc2ccccc2c160 chemicals
O=C(Nc1ccccc1)c1cc2ccccc2oc1=O60 chemicals
O=c1ccc2ccc(OCc3ccccc3)cc2o156 chemicals
O=C(Nc1ccccc1)C1COc2ccccc2O147 chemicals
C(=Cc1ccc2ccccc2n1)c1ccccc145 chemicals
O=C(Nc1ccc2c(c1)OCCO2)c1ccccc144 chemicals
O=S(=O)(Nc1cnc2ccccc2n1)c1ccccc134 chemicals![Scaffold O=c1[nH]c(C=Cc2ccccc2)nc2ccccc12](/scaffold/JDEJRLXMWUYMSS-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(C=Cc2ccccc2)nc2ccccc1232 chemicals
O=C(Nc1ccccc1)c1cc(=O)c2ccccc2o125 chemicals
O=C(Nc1ccccc1)N1CCc2ccccc2C123 chemicals