CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 20 atoms

4 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
4
With full pages
3
Scaffold SMILES

O=C(CNNS(=O)(=O)c1ccccc1)Nc1ccsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNNS(=O)(=O)c1ccccc1)Nc1ccsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

Methyl 3-[(2-{2-[(4-methoxyphenyl)sulfonyl]-1-methylhydrazino}acetyl)amino]-2-thiophenecarboxylate chemical structure, C16H19N3O6S2, CAS 861212-56-8
Methyl 3-[(2-{2-[(4-methoxyphenyl)sulfonyl]-1-methylhydrazino}acetyl)amino]-2-thiophenecarboxylate
CAS 861212-56-8C16H19N3O6S2
Methyl 3-[(2-{2-[(4-fluorophenyl)sulfonyl]-1-methylhydrazino}acetyl)amino]-2-thiophenecarboxylate chemical structure, C15H16FN3O5S2, CAS 861212-54-6
Methyl 3-[(2-{2-[(4-fluorophenyl)sulfonyl]-1-methylhydrazino}acetyl)amino]-2-thiophenecarboxylate
CAS 861212-54-6C15H16FN3O5S2
Methyl 3-[(2-{1-methyl-2-[(4-nitrophenyl)sulfonyl]hydrazino}acetyl)amino]-2-thiophenecarboxylate chemical structure, C15H16N4O7S2, CAS 861212-60-4
Methyl 3-[(2-{1-methyl-2-[(4-nitrophenyl)sulfonyl]hydrazino}acetyl)amino]-2-thiophenecarboxylate
CAS 861212-60-4C15H16N4O7S2
Methyl 3-[(2-{2-[(4-chlorophenyl)sulfonyl]-1-methylhydrazino}acetyl)amino]-2-thiophenecarboxylate chemical structure, C15H16ClN3O5S2, CAS 861212-55-7
Methyl 3-[(2-{2-[(4-chlorophenyl)sulfonyl]-1-methylhydrazino}acetyl)amino]-2-thiophenecarboxylate
CAS 861212-55-7C15H16ClN3O5S2